Clinical trials: Spinal Cord Injury(SCI)
Spinal Cord Injury
Xo-Motion R Exoskeleton in SCI-Adoption Study
After spinal cord injury (SCI), many people lose their ability to walk and do not have access to equipment and assistance that could help them regain functional abilities.
- Trial name
- NCT07380516
- Testing
- XoMotionR- assisted locomotor training
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
SCI - Spinal Cord Injury, Motor Imagery
Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury
The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as…
- Conditions
- SCI - Spinal Cord Injury, Motor Imagery, Brain-Computer Interfaces
- Trial name
- NCT07106060
- Testing
- EEG-based rehabilitation training device (L-B300), EEG-based rehabilitation training device (L-B300)（Not connected）
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shengjing Hospital
Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI)
Myobloc Atrophy Study
The present pilot study is designed to assess the extent to which BOTOX and MYOBLOC cause muscle atrophy in spastic patients. The primary objective is to assess whether there is statistically significant difference in muscle…
- Conditions
- Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI), Brain Injury, Tumor
- Trial name
- MAS (NCT02052024)
- Testing
- Botox, MYOBLOC
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Spinal Cord Injuries (SCI), Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI
This study aims to demonstrate the safety and effectiveness of the Eve personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT06777576
- Testing
- Hands-free exoskeleton
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Spinal Cord Injuries
Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury
Randomized placebo-controlled safety and feasibility study with crossover design (3 arms). Placebo or Rimonabant 2.5mg or Rimonabant 5mg will be administered for 5 days.
- Trial name
- RIMOFATSCI-1 (NCT05398913)
- Testing
- Rimonabant
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Spinal Cord Injury
Indego Exoskeleton After SCI
The purpose of this study is to assess the use of Indego as a gait training tool for subjects with complete or incomplete paraplegia as a result of spinal cord injury (SCI) who have preserved lower extremity function.
- Trial name
- NCT02793635
- Testing
- Indego Powered Exoskeleton
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Parker Hannifin Corporation
Spinal Cord Injury
Re-Inventing Yourself After Spinal Cord Injury
The purpose of this study is to evaluate the efficacy of a replicable, psychologically-based group education intervention, Re-Inventing Yourself after Spinal Cord Injury (SCI), which aims to enhance personal self-efficacy.
- Trial name
- NCT01633164
- Testing
- SCI Reinvention Protocol Participants, Waitlist Group
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Craig Hospital
SCI - Spinal Cord Injury, Spasticity
Addressing Spasticity and Motor Function With Epidural Spinal Cord Stimulation
The purpose of this study is to investigate treating severe spasticity in persons with spinal cord injury by implanting a device in the body that delivers electrical stimulation around the spinal cord (spinal cord epidural…
- Trial name
- NCT07890558
- Testing
- Epidural implant stimulation device
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kessler Foundation
SCI - Spinal Cord Injury
Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular Health
The study is designed to investigate the effects of passive heat therapy on blood vessel health in 40 people (48 enrolled with attrition rate of 20%).
- Trial name
- IIS_SCIDoD (NCT07317843)
- Testing
- HEAT - Passive Heat Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hypotension, Spinal Cord Injury
Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males
To address the effect of tadalafil (Cialis) on the cardiovascular system of men with complete spinal cord injury at T-6 and above. The hypothesis is that tadalafil will cause significant hypotension in people with tetraplegia.
- Trial name
- NCT01067391
- Testing
- tadalafil
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Spinal Cord Injuries (SCI)
Combined TMS-tSCS for Lower Limb Rehabilitation in Chronic Incomplete SCI
he goal of this clinical trial is to learn if combined brain and spinal cord stimulation using TMS-tSCS can improve leg strength and walking recovery in adults with chronic incomplete spinal cord injury.
- Trial name
- NCT07595497
- Testing
- Transcranial Magnetic Stimulation, Transcutaneous Spinal Cord Stimulation
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- National University Hospital, Singapore
Spinal Cord Injury (SCI)
The Effects of L-carnitine on Fatigue in Spinal Cord Injury
1. Purpose: To explore the use of L-Carnitine, a pharmaceutical product, for the treatment of fatigue in persons with spinal cord injury (SCI). 2.
- Trial name
- NCT01232907
- Testing
- L-Carnitine
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Spinal Cord Injury
SCI Epidemiology and Complications
The aim of this study was to epidemiologically evaluate patients diagnosed with spinal cord injury who were admitted to our clinic over the last five years and, unlike similar studies, to investigate the presence of complications…
- Trial name
- NCT07425470
- Testing
- Retrospective data analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bandırma Onyedi Eylül University
Spinal Cord Injury
Corticospinal Function After Spinal Cord Injury
The investigator's overall goal is to develop new strategies to test optimization of Spike-timing-dependent plasticity (STDP) doses to maximize strategy to restore upper and lower-limb motor function in individuals with spinal…
- Trial name
- NCT02451683
- Testing
- Electrophysiology Assessment of Time Domain, Electrophysiology Assessment of Location, Training with some stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries (SCI)
Investigation of the Effects of C-Mill (Hocoma AG, Switzerland) Treadmill Training on Trunk Balance in Patients with Spinal Cord Injury
This study examines how C-Mill treadmill training affects balance and stability in people with spinal cord injury (SCI). Many individuals with SCI experience difficulty with sitting and walking balance, which affects their daily…
- Trial name
- NCT06872931
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS
Rehabilitation interventions such as physical training and neural stimulation after spinal cord injury (SCI) have been shown to increase neural plasticity.
- Trial name
- NCT03851302
- Testing
- Active Remote Ischemic Conditioning, Isometric hand exercise
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Spinal Cord Injuries
Determine the Association Between the Level of SCI With Chronic Respiratory Symptoms, Measures of Pulmonary Function, and Respiratory Illness.
This study is using a standardized method to assess respiratory function in SCI in order to determine the association between level of SCI with chronic respiratory symptoms, measures of pulmonary function, and respiratory…
- Trial name
- NCT00011336
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries (SCI), Blood Pressure
AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury
The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge.
- Conditions
- Spinal Cord Injuries (SCI), Blood Pressure, Thermoregulation, Perfusion Index
- Trial name
- NCT07699094
- Testing
- Controlled Cool Thermal Challenge (18°C)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injury
Skilled Motor Training and tDCS to Improve Leg Function After Spinal Cord Injury
The study investigates the effect of using transcranial direct current stimulation (tDCS) and skilled stepping training versus skilled stepping training with sham-tDCS in improving ankle and leg motor control in persons with…
- Trial name
- SLT (NCT01962675)
- Testing
- Transcranial direct current stimulation + step training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development