Clinical trials: Spinal Cord Injury(SCI)
Spinal Cord Injuries, Acute Traumatic Spinal Cord Injury
Spinal Decompression Plus Nerve Graft Implantation Following TSCI
This is a single-blinded (with outcome assessors blinded to treatment allocation), 12-month pilot study to evaluate of the safety, feasibility, and preliminary efficacy of dorsal myelotomy and expansive duraplasty performed…
- Trial name
- NCT06243211
- Testing
- DMED, ANGI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Francis Farhadi
Spinal Cord Injuries
Long-term PAS in Rehabilitation After SCI
The investigators have recently shown in two pilot incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak…
- Trial name
- NCT03045744
- Testing
- long-term paired associative stimulation
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Spinal Cord Injuries
Task-specificity for Locomotor Recovery Following SCI
The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (> 1 yr) motor incomplete spinal cord injury (iSCI).
- Trial name
- NCT03144388
- Testing
- Variable Stepping Training, Variable Non-specific Training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Spinal Cord Injuries, Neuropathic Pain
Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain.
- Conditions
- Spinal Cord Injuries, Neuropathic Pain, Neurological Injury, Pain
- Trial name
- NCT05492188
- Testing
- Operant Conditioning of Cutaneous Reflexes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Spinal Cord Injury
Precision Versus Endurance Training to Improve Walking After Chronic Incomplete SCI
The objective of the study was to determine the efficacy of two forms of physical therapy training, one emphasizing precise, visually guided walking over obstacles and on targets (Precision Training), the other emphasizing mass…
- Trial name
- NCT01765153
- Testing
- Endurance, Precision
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Alberta
Spinal Cord Injuries
Scale Up of Project Workout on Wheels Internet Intervention (WOWii)
This study is designed is to test the feasibility, fidelity, and effectiveness of scaling up an evidence- and theory-based virtually delivered physical activity intervention (WOWii) for individuals living with chronic SCI for…
- Trial name
- WOWii (NCT05353842)
- Testing
- WOWii Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Craig Hospital
Neuropathic Pain, SCI - Spinal Cord Injury
Transcutaneous Intercostal Nerve Stimulation in Spinal Cord Injury
The purpose of this study is to determine the safety, feasibility, and effectiveness of electric stimulation of the nerves along the intercostal nerves on pain and spasticity in spinal cord injury patients.
- Trial name
- TINS (NCT04506099)
- Testing
- TINS Active protocol
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury, Spinal Cord Injury Cervical
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury.
- Trial name
- NCT06867809
- Testing
- Epidural spinal cord stimulation and paired spine and brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jason Carmel
Spinal Cord Injury, Chronic Pain
Education Interventions for Self-Management of Pain Post-SCI: A Pilot Study
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI). Unfortunately, chronic pain is very difficult to treat.
- Trial name
- NCT02262234
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury, Delayed Admission
Complications Associated With Delayed Admission to Spinal Injury Unit
The aim of this study is to determine the prevalence of complications including PUs at time of admission to a regional spinal injury rehabilitation unit (MCSI), the relationship between wait time to admission for specialist SCI…
- Trial name
- NCT07015099
- Where
- United Kingdom
- Volunteers
- 1,400 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
SCI - Spinal Cord Injury
Improving Balance After Spinal Cord Injury Using a Robotic Upright Stand Trainer and Spinal Cord Epidural Stimulation
The purpose of this study is to understand how standing and sitting balance control is altered after spinal cord injury and how a new type of robotic assistive device may be used with spinal stimulation to improve muscle…
- Trial name
- NCT06650202
- Testing
- The Tethered Pelvic Assist Device (TPAD)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Effect of Suctioning by Bronchoscope on Postoperative Pulmonary Complications Among Patients With SCI in the PACU
Respiratory failure and dyspnea are common in spinal cord injury (SCI), and in acute situations, any spinal cord lesion above T11 can cause abnormal respiratory function and impair the airway clearance.
- Trial name
- NCT04879602
- Testing
- suction with bronchoscopy
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injuries (SCI), Upper Limb Function
FES Arm Cycling on Functional Ability and Strength in People With SCI
The goal of this feasibility study is to determine if Functional Electrical Stimulation (FES) arm cycling can be used to improve arm functional ability and arm strength in people with Spinal Cord Injury (SCI).
- Trial name
- NCT07385456
- Testing
- Functional electrical stimulation (FES) arm cycling
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Glasgow Caledonian University
Chronic Spinal Cord Injury
The Up-LIFT Study of Non-Invasive ARC Therapy for Spinal Cord Injury
The Up-LIFT Study is a prospective, single-arm study designed to evaluate the safety and effectiveness of non-invasive electrical spinal cord stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity…
- Trial name
- Up-LIFT (NCT04697472)
- Testing
- LIFT System
- Where
- 14 sites in United States, Canada and 2 more
- Volunteers
- 65 people
- Sponsor
- ONWARD Medical, Inc.
Spinal Cord Injury
Cold vs. Paraspinal Stimulation for Erectile and Urinary Function in SCI Patients
This study is being conducted to compare the effects of two simple treatments-cold therapy and electrical stimulation applied to the lower back-on sexual function and urinary control in men with spinal cord injury (SCI).
- Trial name
- NCT07101042
- Testing
- Cold Stimulation, Paraspinal Electrical Stimulation
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spinal Cord Injury, Paraplegia, Spinal
tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCI
This clinical trial aims to evaluate the safety and efficacy of transcutaneous spinal cord stimulation (tSCS) combined with rehabilitation training for treating paraplegia after spinal cord injury (SCI).
- Trial name
- tSCScwRT (NCT07907952)
- Testing
- Transcutaneous Spinal Cord Stimulation Combined with Rehabilitation Training
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Spinal Cord Injury, Spinal Cord Disease
Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI
Individuals who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.
- Conditions
- Spinal Cord Injury, Spinal Cord Disease, Spinal Cord Injuries (SCI)
- Trial name
- NCT06698224
- Testing
- Spinal cord transcutaneous stimulation, Paired spinal cord and peripheral nerve stimulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI)
The purpose of this research study is to investigate the effectiveness of a memory retraining program and a processing speed program in a spinal cord injured (SCI) population.
- Trial name
- NCT03985540
- Testing
- Behavorial; memory exercise, Behavioral: speed exercises
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Neuromodulation to Improve Grasping Function After SCI
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI.
- Trial name
- NCT07433959
- Testing
- iTBS, PCMS, Exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Spinal Cord Injuries, Gut Microbiome
Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury
The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline [within 6 weeks of injury], 6, and 12 months after…
- Trial name
- NCT05670288
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Alabama at Birmingham