Clinical trials: Spinal Cord Injury
Spinal Cord Injuries
Functional Interval Training for People With Spinal Cord Injury and Their Care Partners
Functional Interval Training for People with Spinal Cord Injury and Their Care Partners (SCI-FIT) aims to address barriers to physical activity for people with spinal cord injury and their care partners.
- Trial name
- SCI-FIT (NCT05221723)
- Testing
- High Intensity Interval Exercise Training Group
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Spinal Cord Injury, Cardio Vascular Disease
FES Cycling With BFR in the Spinal Cord Injury Population
Cardiometabolic Disease (CMD) is the silent killer within the spinal cord injury/disease (SCI/D) population. Many SCI/D patients' initial CMD presentation is with a heart attack, stroke, or sudden cardiac death, highlighting the…
- Conditions
- Spinal Cord Injury, Cardio Vascular Disease, Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- NCT07588503
- Testing
- Blood Flow Restriction, Functional Electrical Stimulated Cycling
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Dr. B. Catharine. Craven
Spinal Cord Injury
Medico-legality of Acute Spinal Cord Injuries
1. Describe different medico-legal aspects of TSI (mode of trauma, cause and Pattern of spinal injuries). 2. Assess the outcome of TSI in studied cases. 3.
- Trial name
- NCT06717503
- Testing
- data collection
- Volunteers
- 120 people
- Sponsor
- Assiut University
Spinal Cord Injury
Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury
The effect of intrathecal transplantation of autologous adipose tissue derived mesenchymal stem cells in the patients with spinal cord injury, Phase I Clinical study.
- Trial name
- NCT01624779
- Testing
- autologous adipose tissue derived mesenchymal stem cells
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Bukwang Pharmaceutical
Spinal Cord Injury
The Effect of an Exercise Program on Physical Function After a Spinal Cord Injury
This study would focus on adding a group exercise program to the usual therapy delivered in the hospital. We propose to design an exercise program that would be 30 minutes in length, 3 times per week.
- Trial name
- NCT00535210
- Testing
- Cardiovascular training, Balance training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries
Low Oxygen Therapy to Enhance Walking Recovery After SCI.
The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury of different age…
- Trial name
- BO2ST-II (NCT06521723)
- Testing
- Daily acute intermittent hypoxia, Walking + tSTIM
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Spaulding Rehabilitation Hospital
Spinal Cord Injuries (SCI)
Spasticity in SCI Following Acute Intermittent Hypoxia
This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury.
- Trial name
- NCT07583498
- Testing
- Acute Intermittent Hypoxia (AIH)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Zev Rymer
Cervical Spinal Cord Injury
A Comparative Study of High and Low Tidal Volume in Preventing Hypoxemia in Patients With Mechanical Ventilation After Cervical Spinal Cord Injury
This study in order to best tidal volume mechanical ventilation in patients with cervical spinal cord injury (sci) as the research point, through higher low volume Settings to find the difference of two groups of patients to…
- Trial name
- NCT04949971
- Testing
- High volume group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Spinal Cord Injury, Neurological Conditions
Olfactory Cell Transplantation and Intensive Rehabilitation to Repair Chronic Spinal Cord Injury
This is a randomised, blinded and controlled Phase I trial to measure the safety, feasibility and efficacy of a combined cell transplantation and intensive rehabilitation intervention to treat spinal cord injury.
- Conditions
- Spinal Cord Injury, Neurological Conditions, Rehabilitation Exercise
- Trial name
- NCT07596563
- Testing
- Olfactory Ensheathing Cell, biological intervention, rehabilitation
- Volunteers
- 30 people
- Sponsor
- Dr Brent McMonagle
Spinal Cord Injury
Corticospinal Excitability After rTMS in Spinal Cord Injury Patients
A crossover trial with spinal cord injury volunteers will be conducted. Three sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT03014999
- Testing
- High frequency rTMS (repetitive Transcranial Magnetic Stimulation), Low frequency rTMS (repetitive Transcranial Magnetic Stimulation)
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Universidade Federal de Pernambuco
Spinal Cord Injuries
In-Home Adjustment of New Spinal Cord Injury Caregivers
To improve spinal cord injury (SCI) rehabilitation through stronger informal caregiving, the proposed study will modify and evaluate a telehealth Transition Assistance Program (TAP) for informal caregivers of individuals with SCI…
- Trial name
- NCT03244098
- Testing
- Transition Assistance Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Spinal Cord Injuries
Living With Spinal Cord Injury.
A Spinal Cord Injury (SCI) often drastically disrupts the lives of affected patients and their relatives and caregivers. This observational study will provide new knowledge on how patients and their family caregivers cope in the…
- Trial name
- NCT03709732
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 2,654 people
- Sponsor
- St. Olavs Hospital
Spinal Cord Injuries
Electrical Stimulation for Spasticity in Spinal Cord Injury
This study examines the immediate and long-term effects of lumbosacral TENS on spasticity and residual voluntary force control in spinal cord injury in comparison to no TENS.
- Trial name
- NCT05103436
- Testing
- TENS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Spinal Cord Injuries, Paralysis
Functional Electrical Stimulation for Production of Artificial Cough
The purpose of the present study is to assess the utility of abdominal muscle stimulation to provide large positive airway pressures and expiratory airflow thus simulating cough.
- Trial name
- NCT00589199
- Testing
- Placement and use of the device
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- MetroHealth Medical Center
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Acquired Brain Injuries, Spinal Cord Injury
Virtual Reality Rehabilitation for Cognitive, Emotional, and Motor Recovery in Neurological Disorders
This randomized controlled trial (RCT) evaluates the effectiveness of virtual reality (VR) rehabilitation in improving cognitive, emotional, social, and motor functions in patients with neurological disorders (ABI, SCI, MS, PD).
- Conditions
- Acquired Brain Injuries, Spinal Cord Injury, Multiple Sclerosis, Parkinson Disease
- Trial name
- NeuroVR (NCT06838975)
- Testing
- VR Training, traditional cognitive and motor rehabilitation following standard clinical practices
- Where
- 2 sites in Italy
- Volunteers
- 328 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Spinal Cord Injuries
Recovery of Bladder and Sexual Function After Spinal Cord Injury
Bladder and sexual dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord injury.
- Trial name
- NCT03036527
- Testing
- Activity-based locomotor training, Activity-based stand training, Activity-based upper arm ergometry
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Spinal Cord Injuries
Closed-loop Functional Spinal Cord Stimulation in Patients With Spinal Cord Injury
The purpose of this experiment is to evaluate the efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients after Spinal Cord Injury
- Trial name
- COFUN (NCT04969042)
- Testing
- Pins Medical G122 RS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Luming Li
Acute Spinal Cord Injury
Transplantation of Autologous Adipose Derived Stem Cells (ADSCs) in Spinal Cord Injury Treatment
This study is designed to assess the safety and effect of autologous adipose derived stem cell (ADSCs) transplantation in acute spinal cord injury patients. 1.
- Trial name
- NCT02034669
- Testing
- Laminectomy, Intradural space, Intrathecal
- Where
- Vietnam
- Volunteers
- 48 people
- Sponsor
- Tri Phuoc Biotechnology., JSC
Spinal Cord Injury
NeuroRegen Scaffold™ With Bone Marrow Mononuclear Cells Transplantation vs. Intradural Decompression and Adhesiolysis in SCI
The purpose of this study is to investigate the efficacy and safety of NeuroRegen Scaffold with bone marrow mononuclear cells (BMMCs) on neurological recovery following chronic and complete spinal cord injury, compared to the…
- Trial name
- NCT02688062
- Testing
- NeuroRegen Scaffold with BMMCs transplantation, Surgical intradural decompression and adhesiolysis
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Chinese Academy of Sciences