Clinical trials: Spinal Cord Trauma
Spinal Cord Injuries, Depression
Telepsychology in Spinal Cord Injury
This study will determine the effectiveness of tele-psychology in treating persons with spinal cord injury (SCI) with depressed mood in the early period post-rehabilitation discharge.
- Trial name
- NCT03711760
- Testing
- telepsychology
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Santa Clara Valley Health & Hospital System
Spinal Cord Injuries, Urinary Incontinence
Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries
The goal of this study is to determine whether administration of sildenafil will decrease urine leakage in patients with spinal cord injuries.
- Trial name
- NCT04565925
- Testing
- Sildenafil Citrate
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Spinal Cord Injuries
Upper Limb Spinal Cord Stimulation for Rehabilitation Enhancement
In the United Kingdom, there are more than 1000 new cases of spinal cord injury (SCI) each year, with around half of these injuries affecting the cervical spine.
- Trial name
- Up-Stim (NCT05991804)
- Testing
- Transcutaneous spinal cord stimulation added to inpatient rehabilitation
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Spinal Cord Injury
Treatment of Spinal Cord Injury Using Autologous Concentrated Growth Factors
Spinal cord injury (SCI) is a severe disorder of the central nervous system, and effective clinical management remains a significant global challenge.
- Trial name
- NCT07253233
- Testing
- Concentrated Growth Factors (CGF)
- Volunteers
- 10 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Spinal Cord Injuries and Disorders (SCI/D)
Caring Connections: A Program to Alleviate Social Isolation and Loneliness in Individuals Living With Spinal Cord Injury
This study will use a randomized controlled design with an active attention control group to evaluate an intervention intended to reduce social isolation and loneliness in persons with SCI/D.
- Trial name
- NCT05295108
- Testing
- Caring Connections, Attention control
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Chicago Association for Research and Education in Science
Spinal Cord Injuries, Complete Spinal Cord Injury
The Efficacy and Safety of a New Power Exoskeleton Robot for Improving Walking Ability in Spinal Cord Injury Patients
In Taiwan, there are more than 23,000 individuals with spinal cord injuries (SCI, mean age: 27 years), with an increment of new 1,200 SCI individuals each year.
- Conditions
- Spinal Cord Injuries, Complete Spinal Cord Injury, Incomplete Spinal Cord Injury
- Trial name
- NCT03548649
- Testing
- exoskeleton robot training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Spinal Cord Injuries, Paraplegia
Interactive Telehealth for Wheelchair Users
During typical daily activity, people with established spinal cord injury perform significantly fewer pressure-relief maneuvers than the recommended frequency while overestimating their adherence on recall surveys of pressure…
- Conditions
- Spinal Cord Injuries, Paraplegia, Pressure Ulcer, Buttock
- Trial name
- NCT04266808
- Testing
- An interactive telehealth monitoring and biofeedback system, Education Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rancho Research Institute, Inc.
Spinal Cord Injuries, Pain, Neuropathic
Using NI-ES to Treat Spinal Cord Injury (SCI)
NI-ES therapy is a treatment that is being studied to potentially treat pain associated with SCI and may help movement below the injury site.
- Trial name
- NCT04097015
- Testing
- Alpha-Stim M
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- SCI Research Advancement
Spinal Cord Injury
The Effect of FES on Children With Spinal Cord Injury
Regular exercise is strongly recommended to help maintain a healthy lifestyle. Unfortunately, children and young adults with damaged spinal cords may not be able to exercise regularly.
- Trial name
- NCT00291317
- Testing
- RT 300-P FES Cycle
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Specialized Hospital
Spinal Cord Injuries
High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation
The purpose of this study is to see if it's possible to reach high cardiovascular intensity training parameters (exercise at a rate that elevates heart rate to the level recommended for improving strength and endurance) while…
- Trial name
- HIT Exo IP (NCT04973852)
- Testing
- Ekso
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries, Reliability
Reliability and Validity of the Spinal Cord Injury Secondary Conditions Scale
People living with spinal cord injury (SCI) experience a range of secondary health conditions that impact their quality of lives.
- Conditions
- Spinal Cord Injuries, Reliability, Validity
- Trial name
- NCT05935943
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Stroke, Spinal Cord Injuries (Complete and Incomplete)
EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation
This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury.
- Trial name
- NCT07705256
- Testing
- Visual EMG feedback with vibrotactile feedback, Visual EMG feedback
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Spinal Cord Injuries
AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI
Locomotor training (LT) facilitates recovery of spinal locomotor networks after incomplete spinal cord injury (ISCI), but walking impairments persist.
- Trial name
- NCT05700942
- Testing
- High Dose Intervention-tsDCS, Low Dose Intervention-tsDCS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Autonomic Dysreflexia
Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)
This study will be investigating the effects of fesoterodine on autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI).
- Trial name
- NCT02676154
- Testing
- Fesoterodine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Incomplete Spinal Cord Injury
A Telerehabilitation Program for SCI
This study evaluates a remotely supervised, home-based therapeutic program to improve upper-limb voluntary movement in adults with tetraplegia caused by incomplete spinal cord injury (iSCI).
- Trial name
- NCT04977037
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Neurogenic Bowel
Improving Bowel Function and Quality of Life After Spinal Cord Injury
Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury.
- Trial name
- NCT03949660
- Testing
- Stimulation for blood pressure without stand, Stimulation for blood pressure with stand, Stimulation for trunk and core without stand
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Neurogenic Overactive Bladder, Urinary Incontinence
Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
The study is designed to demonstrate that treatment with low level stimulation of the bladder muscles reduces symptoms of urinary incontinence in comparison with no stimulation.
- Conditions
- Neurogenic Overactive Bladder, Urinary Incontinence, Detrusor Overactivity
- Trial name
- ACCEPTANCE (NCT01023269)
- Testing
- InterStim Therapy
- Where
- 8 sites in Belgium, France and 4 more
- Volunteers
- 17 people
- Sponsor
- MedtronicNeuro
Spinal Cord Injuries
Self-Management Across the Care Continuum
Persons with spinal cord injury (SCI) face many challenges as they transition from inpatient care to outpatients and on into the community.
- Trial name
- NCT04540679
- Testing
- VIP4SCI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Cord Injuries, Neurogenic Bladder
Below the Belt: Non-invasive Neuromodulation to Treat Bladder, Bowel, and Sexual Dysfunction Following Spinal Cord Injury
Recent findings have demonstrated that electrical stimulation to the spinal cord (i.e. implanted electrodes) can significantly recover bladder, bowel, and sexual function after injury.
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder, Neurogenic Bowel, Spinal Cord Stimulation
- Trial name
- NCT04604951
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries
VO2peak and Exercise Efficiency in Upper-body Poling
This study compares peak oxygen uptake (VO2peak) and exercise efficiency in upper-body poling versus arm crank ergometry in trained able-bodied and paraplegic participants.
- Trial name
- NCT03284086
- Testing
- upper-body double-poling, arm crank ergometry
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
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