Clinical trials: Spinal Decompression
Decompression, Surgical
A Study on the Use of Educational Programs Prior to Lumbar Spinal Surgery
This study evaluated the hypothesis that the implementation of an educational program that informs spine patients about their condition, treatment options, prioritization on the wait list, and post-operative care would improve…
- Trial name
- NCT00719485
- Testing
- Educational program
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
Spine Tumor, Spine Metastases
Spine Oncology Registry
This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.
- Conditions
- Spine Tumor, Spine Metastases, Spine Cancer
- Trial name
- NCT07225491
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Spinal Cord Diseases
Comparison of Cervical Laminectomy to Laminoplasty
The objective of this study is to compare the clinical and radiographic outcomes of multi-level laminectomy to multi-level laminoplasty in the treatment of patients with cervical myelopathy or myeloradiculopathy.
- Trial name
- NCT01324622
- Testing
- Laminoplasty, laminectomy
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Synthes USA HQ, Inc.
Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.
Perioperative Melatonin in Lumbar Laminectomy
Patients undergoing lumbar laminectomy surgery will receive either 5 or 10 mg melatonin or placebo once the evening before surgery and again 90 minutes before surgery.
- Trial name
- NCT01126294
- Testing
- 5 mg melatonin, 10 mg melatonin
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Degenerative Spinal Arthritis, Cervical Myelopathy
Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion
This research study is being conducted to help improve the pre-operative, intra-operative, and post-operative course for patients and enhance recovery.
- Conditions
- Degenerative Spinal Arthritis, Cervical Myelopathy, Spinal Stenosis
- Trial name
- NCT04315090
- Sponsor
- Mayo Clinic
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Spinal Cord Injury
Optimal Treatment for Spinal Cord Injury Associated With Cervical Canal Stenosis (OSCIS) Study
Controversy exists regarding the optimal management of acute traumatic cervical spinal cord injury (SCI), especially those without bone injury.
- Trial name
- OSCIS (NCT01485458)
- Testing
- Early surgery, Delayed surgery
- Where
- Japan
- Volunteers
- 72 people
- Sponsor
- Tokyo University
Syndrome, Manganese Neurotoxicity
Effects of Thoracolumbar Stabilization Versus Spinal Decompression Exercises on Maigne's Syndrome
The study was conducted to compare the effect of thoracolumbar stabilization exercises versus spinal decompression exercises on pain, range of motion, disability and posture in patients with maigne's syndrome.
- Trial name
- NCT07426900
- Testing
- Lumbothoracic stabilization exercises, Spinal decompression exercises, Standardized physical therapy treatment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Laminectomy
Preemptive Analgesia for Postlaminectomy
To relieve post laminectomy pain, we have tried intraoperative perineural injection of lidocaine right after the exposure in expecting that this would be preemptive analgesia by blocking the nerve transmission so that…
- Trial name
- NCT00656526
- Testing
- Lidocaine, perineural injection, intraoperatively, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Harran University
Lumbar Radiculopathy
Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes
This randomized control trial will compare opioid use, pain, and functional outcomes following decompression surgery for single-level lumbar radiculopathy in patients who undergo placement of corticosteroid epidural injection…
- Trial name
- NCT03543033
- Testing
- Corticosteroid injection
- Where
- United States
- Sponsor
- Lahey Clinic
Lumbosacral Spinal Stenosis
Irrigation Endoscopic Decompressive Laminotomy
The classic laminectomy for surgical treatment of spinal stenosis has considerable morbidity .This is further magnified by the disease being more common in elderly with associated medical comorbidities and being usually global…
- Trial name
- NCT01991912
- Testing
- open lumbar decompression
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Neck Pain
C3 Laminectomy With Cervical Laminoplasty
1. Background In cervical stenosis, cervical laminoplasty from the third to sixth cervical vertebrae is widely used. However, the muscles attached to the C2, which play an important role in the movement of our neck, are…
- Trial name
- NCT06374680
- Testing
- laminectomy at C3 level
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot
Nerve Decompression for Ulcer Recurrence Avoidance (DURA)
Anecdotal reports and scientific literature suggest that the risk of recurrence of diabetic foot ulcers can be minimized by nerve decompression procedures at anatomic sites of nerve pinching and entrapment.
- Conditions
- Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot, Diabetic Polyneuropathy
- Trial name
- DURA (NCT01762085)
- Testing
- nerve decompression
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- Association of Extremity Nerve Surgeons
Spinal Stenosis, Spinal Stenosis Lumbar
Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is characterized by low back and leg pain, walking disturbances and sometimes instability, impaired balance and numbness of the lower limbs.
- Conditions
- Spinal Stenosis, Spinal Stenosis Lumbar, Degeneration Lumbar Spine, Degeneration Spine
- Trial name
- UppSten (NCT03495661)
- Testing
- Decompression
- Where
- Sweden
- Volunteers
- 156 people
- Sponsor
- Uppsala University
Low Back Pain
Pilot Study to Evaluate The Effectiveness And Safety Of Axiom Worldwide Drx9000™ Spinal Decompression System
This pilot study will evaluate the effectiveness and safety of the Axiom Worldwide DRX9000 for active treatment of chronic low back pain.
- Trial name
- NCT00414596
- Testing
- DRX9000™
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- NEMA Research, Inc.
Spinal Stenosis
Surgical Versus Nonsurgical Treatment for Spinal Stenosis
Lumbar spinal stenosis (a narrowing of spaces in the backbone that results in pressure on the spinal cord and/or nerve roots) is a condition that occurs frequently, particularly in the elderly.
- Trial name
- NCT00022776
- Testing
- Surgical decompression, Physical therapy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Pittsburgh
Degenerative Cervical Myelopathy (DCM)
Cervical Laminectomy With or Without Lateral Mass Fixation in Cervical Spondylotic Myelopathy
The cervical spine consists of seven cervical vertebrae joined by intervertebral disks and a complex network of ligaments. The cervical spine has a normal lordotic curve, and it is much more mobile than the thoracic or lumbar…
- Trial name
- NCT06045663
- Testing
- laminectomy without lateral mass fixation, laminectomy with lateral mass fixation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Seroma, Lumbar Spine Decompression
Management of Seroma After Posterior Lumbar Spine Decompression
The aim of this study is to evaluate the clinical presentation and management strategies of seroma formation following posterior lumbar spine decompression.
- Trial name
- NCT07060781
- Testing
- Posterior Lumbar Spine Decompression
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kafrelsheikh University