Clinical trials: Spinal Decompression
Intermittent Neurogenic Claudication (INC) as a Result of Spinal Stenosis
A Randomized Controlled Trial Comparing Surgical Decompression With an Interlaminar Implant in Patients With Intermittent Neurogenic Claudication Caused by Lumbar Stenosis
A Randomized, Blinded Comparison of Surgical Intervention with the Coflex® Interspinous Implant versus Surgical Decompression for Patients with Intermittent Neurogenic Claudication caused by Lumbar Stenosis
- Trial name
- FELIX (NCT01727752)
- Testing
- Decompression
- Where
- 13 sites in Netherlands
- Volunteers
- 386 people
- Sponsor
- Paradigm Spine
Lumbar Spinal Stenosis
MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
This is a multi-center, prospective, patient outcomes assessment of Minimally Invasive Lumbar Decompression with the Mild® devices in patients with symptomatic central canal spinal stenosis.
- Trial name
- NCT01082159
- Testing
- lumbar decompression
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Vertos Medical, Inc.
Lumbar Canal Stenosis, Lumbar Spinal Stenosis
Is it Really Necessary Going All Over the Top in Patients With Symptomatic Lumbar Spinal Stenosis?
The goal of this clinical trial is to evaluate the theory of epidural pressure by comparing a surgical procedure that aims to perform less bone resection compared to conventional surgery in patients with lumbar spinal stenosis.
- Conditions
- Lumbar Canal Stenosis, Lumbar Spinal Stenosis, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07026305
- Testing
- Pressure-guided laminectomy (PGL), Laminectomy without pressure guidance (LWPG)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Low Back Pain, Herniation, Disc
Non-surgical Spinal Decompression Therapy and Outcomes
This project will determine the clinical utility of non-surgical spine decompression for chronic low back pain (LBP). LBP is one of the highest incidence medical conditions that contributes to disability, decreased activities of…
- Conditions
- Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal
- Trial name
- RESTORE (NCT06525896)
- Testing
- NSSD
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of South Florida
Low Back Pain, Chronic Low-back Pain
AuriculoTherapy NeuroImaging
This is a clinical study of patients who have low back pain (for at least 6 months). The goal is to understand, with brain imaging, how auriculotherapy (an acupuncture-like stimulation of the ear) may work to relieve pain.
- Conditions
- Low Back Pain, Chronic Low-back Pain, Back Pain, Low, Lumbar Disc Disease
- Trial name
- ATNI (NCT06825390)
- Testing
- Cryo-auriculotherapy, Experimental auricular stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Keith M Vogt
Lumbar Spinal Stenosis, Spinal Stenosis
Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Long-term clinical results of two methods of surgical treatment (spinal decompression with or without fusion) in patients with single-level lumbar stenosis will be compared.
- Conditions
- Lumbar Spinal Stenosis, Spinal Stenosis, Spinal Fusion
- Trial name
- NCT05273879
- Testing
- decompression, fusion
- Where
- 2 sites in Russia
- Volunteers
- 86 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Lumbar Spinal Stenosis, Intervertebral Disc Degeneration
Minimally Invasive Decompression and Fusion Versus Open for Degenerative Lumbar Stenosis
The purpose of this study is to determine the effectiveness of minimally invasive decompression and fusion over the traditional open decompression and fusion in patients with single-level lumbar stenosis caused by degenerative…
- Trial name
- NCT04594980
- Testing
- lumbar fusion
- Where
- Russia
- Volunteers
- 96 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Failed Back Surgery Syndrome, Post-Laminectomy Syndrome
SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study
The purpose of the study is to demonstrate safety and efficacy of spinal cord stimulation with peripheral nerve field stimulation for the treatment of chronic low back and leg pain.
- Conditions
- Failed Back Surgery Syndrome, Post-Laminectomy Syndrome, Low Back Pain
- Trial name
- SENSE (NCT01990287)
- Testing
- SCS and PNfS, SCS Alone
- Where
- 28 sites in United States
- Volunteers
- 38 people
- Sponsor
- Abbott Medical Devices
Shoulder Impingement Syndrome, Subacromial Impingement Syndrome
Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Subacromial Decompression Surgery
This randomised prospective controlled trial will investigate patients with impingement syndrome who undergo arthroscopic subacromial decompression.
- Trial name
- GAME (NCT02705521)
- Testing
- Exergames- Laptop and MIcrosoft Kinect
- Where
- 3 sites in United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Postoperative Pain
Fentanyl 12 Mcg Transdermal Patch For Postoperative Pain
The investigators designed a prospective randomized study to investigate the effect of fentanyl 12 mcg transdermal patch on postoperative pain following unilateral, single-level laminectomy/discectomy.
- Trial name
- NCT03199157
- Testing
- Fentanyl transdermal patch
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Baskent University
Chronic Low Back Pain
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements.
- Trial name
- NCT00899600
- Testing
- Ketamine, Normal saline
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lumbar Spinal Stenosis
Minimal Invasive Surgery Versus Interlaminar Decompression in Lumbar Canal Stenosis
Conventional open surgery has been shown to be an effective procedure for LCS decompression. Minimally invasive surgery (MIS) through tubular retractors is a recently introduced alternative procedure for decompression of LCS.
- Trial name
- NCT05147064
- Testing
- minimally invasive surgery, conventional open surgery
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cervical Disc Prolapse
Functional Outcome After Combined Posterior Laminectomy and Anterior Cervical Discectomy and Fusion for Large Cervical Disc Prolapse
Cervical disc herniation (CDH) is the result of the displacement of the nucleus pulposus of the intervertebral disc, which may result in impingement of the traversing nerves as they exit the neural foramen or directly compressing…
- Trial name
- NCT06847503
- Volunteers
- 25 people
- Sponsor
- Assiut University
Lumbar Disc Prolapse With Radiculopathy
Safety Study of ARO Spinal System as an Adjunct to Lumbar Decompression
To evaluate the clinical safety and effectiveness of the ARO Spinal System and to assess preliminary cost/benefit analysis in patients undergoing decompression surgery for symptomatic lumbar disc herniations.
- Trial name
- NCT01970514
- Testing
- ARO Spinal System
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- ARO Medical
Lumbar Spondylolisthesis
Clinical Study of Bilateral Decompression With Interbody Fusion for Spondylolisthesis
Laminectomy with PLIF has been shown to achieve satisfactory clinical outcomes, but it leads to potential adverse consequences associated with extensive disruption of posterior bony and soft-tissue structures.
- Trial name
- NCT02972190
- Testing
- Bilateral decompression with TLIF, laminectomy with PLIF, Pedicle screw and interbody cage
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Evoked Potentials, Visual
A Novel Method for Capturing the Visual Evoked Potential During Spine Surgery Under Total Intravenous Anesthesia
Spine surgery in the prone position (which involves lying face down) is associated with various visual changes, ranging from temporary changes in acuity (or sharpness) to permanent blindness.
- Trial name
- VEP (NCT02563028)
- Testing
- SightSaver Visual Stimulator
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Opioid Use, Pain, Postoperative
Opioid Dispenser for Microdiscectomy/Laminectomy
The opioid crisis continues to plague the United States. While great strides have been made nationwide to decrease overprescribing, improvements are still needed to appropriately educate patients on the safe and responsible use…
- Conditions
- Opioid Use, Pain, Postoperative, Medical Device, Laminectomy
- Trial name
- NCT06358040
- Testing
- Opioid-Dispensing Device, App, Standard Opioid Pill Bottle
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Myelopathy, Compressive, Radiculopathy, Cervical
Can Prophylactic Foraminotomy Prevent C5 Palsy
C5 palsy (C5P) is a well-known, although rare complication of cervical spine decompression surgery. In severe forms, C5P causes debilitating upper extremity weakness involving the deltoids and/or biceps brachii muscles…
- Conditions
- Myelopathy, Compressive, Radiculopathy, Cervical, C5 Palsy
- Trial name
- NCT03023696
- Testing
- Bilateral Cervical Keyhole Foraminotomy, Cervical Decompression
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- The Cleveland Clinic
Spinal Cord Compression, Neoplasm Metastasis
Stereotactic Radiosurgery in Metastatic Spinal Cord Compression
To determine whether stereotactic radiosurgery of metastatic spinal cord compression is equivalent to decompressive surgery followed by external body radiation therapy to maintain ability to walk at 6 weeks.
- Trial name
- Stereocord (NCT02167633)
- Testing
- Decompression surgery, Radiosurgery, Fractionated Radiotherapy
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet