Clinical trials: Spinal Disorder
Post-spinal Anesthesia Hypotension
Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension
The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.
- Trial name
- NCT04780139
- Testing
- Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Diphtheria, Tetanus
A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults
This is a single-center, randomized, active-controlled, parallel-group, open-label, phase I study to evaluate safety and immunogenicity of single injection of LBVD or Eupenta co-administered with Imovax Polio in healthy adults.
- Conditions
- Diphtheria, Tetanus, Pertussis, Poliomyelitis
- Trial name
- NCT03208101
- Testing
- DTP-HepB-IPV-Hib vaccine, DTP-HepB-Hib vaccine & IPV
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- LG Chem
Scoliosis Idiopathic Adolescent, Cyberchondria
Cyberchondria in Adolescents With Idiopathic Scoliosis
Scoliosis is a three-dimensional torsional deformity of the spine and trunk characterized by alignment abnormalities in the coronal plane, the presence of axial rotation in the horizontal plane, and abnormalities in the normal…
- Trial name
- NCT07481071
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Spinal Cord Injury + Peripheral Nerve Diseases
Assessment of Neuropathic Pain
Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases.
- Trial name
- NCT02138344
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Anaesthesia, Spinal
Pain Control and Side Effects in Cesarean Section Anesthesia: Comparison of Intrathecal Morphine and Fentanyl
Intrathecal opioids are frequently combined with local anesthetics to optimize spinal anesthesia for cesarean delivery. Fentanyl, a lipophilic opioid, offers rapid onset and enhanced intraoperative analgesia.
- Trial name
- FvMinSACS (NCT07144410)
- Testing
- fentanyl + morphine, fentanyl
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oradea
Amyotrophic Lateral Sclerosis
Establishment of a Tissue Bank (Blood, CSF) for the Understanding of Motor Neuron Disease (MND)
Biomarkers are essential for the identification of disease states. There are no early diagnostic or prognostic markers for ALS. The purpose of this study is to identify a panel of biomarkers from blood or spinal fluid of ALS…
- Trial name
- WBC (NCT01950910)
- Where
- United States
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
The Spirometry;, The Strength of Respiratory Muscles - MIP, MEP;
Short-term Effects of the Simultaneous Use of Two Physiotherapeutic Methods in the Treatment of Adolescent Idiopathic Scoliosis - Pilot Study
The assessment of influence joint physiotherapy (DoboMed and OMT Kaltenborn - Evjenth) on the function of the respiratory system and the morphology of the ribcage in short-term intensive physiotherapy.
- Conditions
- The Spirometry;, The Strength of Respiratory Muscles - MIP, MEP;, Kyphosis (Plurimeter-V), The Angle of Trunk Rotation in Thoracic Part
- Trial name
- NCT01250860
- Testing
- Derotational manual therapy techniques in selected segments in spine
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Central Cord Syndrome
The Natural History of Traumatic Spinal Cord Injury Using fMRI, MRS and DTI
Traumatic spinal cord injury is a common injury to the spine and can lead to a clinical syndrome called central cord syndrome (CCS).
- Trial name
- NCT00790361
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Muscular Atrophy
Newborn Screening for Spinal Muscular Atrophy
To test if the routine newborn screening dried blood spots can be used to test if missing 2 copies of SMN1 gene, a status indicating spinal muscular atrophy
- Trial name
- NCT02123186
- Testing
- newborn screening test for SMA
- Where
- Taiwan
- Volunteers
- 120,267 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spina Bifida
QUALAS Validation in Dutch
Rationale Patients with spina bifida often experience a decreased quality of life compared to patients without spina bifida. The Quality of Life Assessment for Spina Bifida (QUALAS) is a validated questionnaire to assess the…
- Trial name
- NCT06723951
- Testing
- QUALAS survey
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Spinal Cord Injury
Enhancing STDP After Spinal Cord Injury
The overall goal is to develop new clinical approaches to restore limb function after spinal cord injury (SCI). Corticospinal tract (CST) axons are involved in controlling limb function.
- Trial name
- NCT02701777
- Testing
- STDP, Training, Multisite-STDP
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neurogenic Bladder, Spinal Cord Injuries
Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
The investigators goal is to create a better understanding of patient reported outcomes for bladder management strategies (clean intermittent catheterization (CIC), indwelling catheter (IDC) and bladder surgery.
- Conditions
- Neurogenic Bladder, Spinal Cord Injuries, Quality of Life, Incontinence
- Trial name
- NBRG-PCORI (NCT02616081)
- Testing
- Clean Intermittent Catheterization, Indwelling Catheter, Surgery
- Where
- 3 sites in United States
- Volunteers
- 1,479 people, healthy volunteers welcome
- Sponsor
- University of Utah
Level of Immunity Against Poliovirus Infection
Study of Inactivated Poliovirus Vaccine Given at an Earlier Schedule With Shorter Intervals
The purpose of this study was to evaluated the effectiveness of inactivated poliovirus vaccine at a vaccine schedule that is commonly used in developing countries.
- Trial name
- NCT00260312
- Testing
- Inactivated Polio Vaccine given at an accelerated schedule
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pan American Health Organization
Tumor of Spinal Cord
Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection
Objective to construct the related early activity program for patients with lumbar intraspinal tumor after hemilaminectomy, and evaluate the postoperative limb function exercise according to the content of the program.
- Trial name
- NCT04968730
- Testing
- Postoperative rehabilitation nursing
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Multiple Sclerosis, Balance
Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration.
- Trial name
- NCT07648277
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Tetraplegia, Hypothermia
Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
The ability to maintain normal core body temperature (Tcore = 98.6°F) is impaired in persons with a cervical spinal cord injury (tetraplegia).
- Conditions
- Tetraplegia, Hypothermia, Mild Cognitive Impairment
- Trial name
- NCT02379156
- Testing
- Midodrine Hydrochloride, Cool Temperature
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Lumbar Disc Herniation, Lumbar Disc Disease
Effects of Kinesio Taping on Pain, Endurance, Proprioception, Mobility and Disability in Lumbar Disc Herniation
In addition to the physical therapy program, taping was applied to 90 patients diagnosed with lumbar disc herniation. 90 patients were randomized into 3 groups.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Chronic Pain
- Trial name
- NCT06777095
- Testing
- Routine Treatment + I Taping, Routine Treatment + Star Taping, Routine Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Psoriatic Arthritis, Psoriasis
Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis
The objective of the study is to investigate pain mechanisms, comorbidity status, biomarkers, patient reported outcome measures, ultrasonographic (US) inflammatory activity and association between these features in patients with…
- Conditions
- Psoriatic Arthritis, Psoriasis, Healthy Controls
- Trial name
- PIPA (NCT02572700)
- Testing
- Clinical examination, blood sampling, ultrasonic assessment, and questionnaires
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Adolescent Idiopathic Scoliosis (AIS)
Investigation of Shoulder Position, Upper Extremity Proprioception, and Function in Adolescents With Idiopathic Scoliosis Using Braces
This study aims to investigate the effects of brace use on shoulder position, upper extremity proprioception, and upper extremity function in adolescents with idiopathic scoliosis.
- Trial name
- NCT06904157
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gözde Yagci (Gür)
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