Clinical trials: Spinal Fracture, open to volunteers
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Gait and Bone Health in SMA
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT.
- Trial name
- NCT07400198
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Jacqueline Montes
Osteoporotic Vertebral Fracture, Neuropathic Pain
Osteoporotic Fracture and Lidocaine Plaster 5% for Neuropathic Pain preventioN
Osteoporotic vertebral fractures may lead to chronic pain with a neuropathic component, which is often underdiagnosed and undertreated in older adults.
- Trial name
- FLYNN (NCT07691359)
- Testing
- Lidocaine 5% medicated plaster
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark
Facet Joint Arthritis, Facet Joints; Degeneration
Reliability and Reproducibility of CT-Based Facet Joint Measurements in Patients With AOSpine Type A2, A3, and A4 Thoracolumbar Fractures
The Reliability Evaluation of Facet joint Assessment by Computed Tomography in thoracolumbar fractures (REFACT) study aims to evaluate how consistently different specialists assess thoracolumbar facet joints on computed…
- Conditions
- Facet Joint Arthritis, Facet Joints; Degeneration, Facet Joint Disease, Intervertebral Disk Degeneration
- Trial name
- REFACT (NCT07670039)
- Testing
- Computed Tomography Image Review
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Abdominal Injury, Pelvic Fracture
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of "occult" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the…
- Conditions
- Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury
- Trial name
- NEXUS AP CT (NCT04937868)
- Testing
- There are no interventions associated with this study
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- University of California, Los Angeles
Thoracolumbar Spine Fracture, Facet Joint Degeneration
Degenerative Changes After Treatment of Thoracolumbar Junction Fractures
This observational study will evaluate how degenerative changes in the facet joints and intervertebral discs develop over time after treatment of AOSpine type A2, A3, and A4 fractures of the thoracolumbar junction.
- Conditions
- Thoracolumbar Spine Fracture, Facet Joint Degeneration, Intervertebral Disc Degeneration
- Trial name
- NCT07672184
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sklifosovsky Institute of Emergency Care
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Spine Fracture, Degenerative Disc Disease
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Multicenter Post market clinical follow-up Study on the Safety and Performance of Ennovate® Cervical - Prospective, pure data collection of all Ennovate Cervical patients in Total Indications
- Conditions
- Spine Fracture, Degenerative Disc Disease, Spinal Instability, Spinal Tumor
- Trial name
- CERISE (NCT05296889)
- Testing
- posterior stabilization for the cervical spine
- Where
- 4 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Aesculap AG
Back Pain, Stress Fracture
Posterior Lumbar Stress Reaction in Pediatric Patients. Treatment With or Without Soft Spinal Brace?
A clinical trial will be conducted comparing healing of a posterior lumbar vertebra stress reaction in children treated either with cessation of sports activities for a period of six weeks and wearing a soft spinal brace 16 hours…
- Trial name
- NCT04533178
- Testing
- soft spinal brace, Resting from all sports activities
- Where
- 4 sites in Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Hip Fractures
Pericapsular Nerve Group Block Versus Femoral Nerve Block Study
Hip fractures are common in older adults and are often associated with severe pain, making it difficult for patients to sit for spinal anesthesia before surgery.
- Trial name
- NCT07717463
- Testing
- Ultrasound-Guided Pericapsular Nerve Group (PENG) Block, Ultrasound-Guided Femoral Nerve Block, Spinal Anesthesia (bupivacaine)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Spine Fracture
Three Dimensional Gait Analysis and Electromyography After Stabilisation of Thoracolumbar Spine Fractures Focusing on Possible Temporal Diferences in Physiological Gait Recovery Through Comparison of Open and Minimally Invasive Approaches.
We prospectively enrolled patients with a thoracic or lumbar spine fracture indicated for instrumented posterior stabilization. We consequently randomized the patient for either a conventional open approach procedure or minimally…
- Trial name
- NCT07516834
- Testing
- spine stabilization
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Cervical Spine Fractures, Cervical Spine Injury
Study on Orthosis in Cervical Spine Fracture Treatment
Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults.
- Conditions
- Cervical Spine Fractures, Cervical Spine Injury, Rigid Collar
- Trial name
- SOFT (NCT06848660)
- Testing
- A rigid cervical collar
- Where
- 6 sites in Sweden
- Volunteers
- 616 people
- Sponsor
- Uppsala University Hospital
SMA - Spinal Muscular Atrophy
Adrenal& Bone Complications in Paediatric Patients Living With Spinal Muscular Atrophy (SMA)
Spinal muscular atrophy (SMA) is a genetic disorder that is known to cause damage to specialised nerve cells, called motor neurons.
- Trial name
- SMA-ABC (NCT07530926)
- Where
- United Kingdom
- Volunteers
- 550 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
SPINAL Fracture, Burst Fracture
Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine.
- Conditions
- SPINAL Fracture, Burst Fracture, Spinal Instability of Thoracolumbar Region
- Trial name
- A34RCT (NCT05769114)
- Testing
- Surgical stabilization
- Where
- 2 sites in Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Osteoporosis, Vitamin C Deficiency
Link Between ASCorbemia Level and Osteoporosis
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis.
- Conditions
- Osteoporosis, Vitamin C Deficiency, Vertebral Fractures
- Trial name
- ASCO (NCT07660484)
- Testing
- Plasma vitamin C assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spine Degeneration, Spine Spondylosis Thoracic
Clariance ErYs Registry
International, prospective, single arm, multicenter and observational Post-Market Clinical Follow-up (PMCF). The overall objective of this study is to collect preoperative, intraoperative and postoperative (at 9 weeks, 6 months…
- Conditions
- Spine Degeneration, Spine Spondylosis Thoracic, Spinal Deformity, Spinal Tumor
- Trial name
- ErYs (NCT05170815)
- Testing
- Spine surgery
- Where
- France
- Volunteers
- 760 people
- Sponsor
- Clariance
Spinal Stenosis, SPINAL Fracture
Evaluation of the Evolution of Patient Care Within the Spinal Pathology Department
Spinal conditions are a major public health issue. Their management by surgical treatment is constantly improving and surgical procedures or implantable medical devices are experiencing significant progress.
- Conditions
- Spinal Stenosis, SPINAL Fracture, Vertebral Osteomyelitis, Vertebral Metastasis
- Trial name
- SPINDATA (NCT07627282)
- Testing
- self-administered questionnaire
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- University Hospital, Bordeaux
Vertebral Fracture, Osteoporosis
A Prospective Observational Study of Artificial Intelligence Morphometric Evaluation of Vertebral Fractures
The study will be conducted as a monocentric observational prospective study design wants to evaluate the prevalence of vertebral fractures in the cohort of patients that perform a chest-abdomen CT for medical indication other…
- Trial name
- NCT06449742
- Testing
- AI software and automatic 3D reconstruction
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS San Raffaele
Hip Fracture, Postoperative Pain
Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Trial name
- META-SIFI (NCT07612761)
- Testing
- Ultrasound-Guided Meta-PENG Block, Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO