Clinical trials: Spinal Fracture
Hip Fractures
MED90 of Ropivacaine for Peripheral Nerve Block on Posture-evoked Pain in Spinal Anesthesia Positioning
This study aims to determine the minimum effective dose of ropivacaine for peripheral nerve block on posture-evoked pain for spinal anesthesia in elderly patients with hip fracture.
- Trial name
- NCT04705974
- Testing
- Fascia iliaca block, Femoral nerve block, Pericapsular nerve group block (PENG block)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Huazhong University of Science and Technology
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lower Limb Fracture
Comparison of Postoperative Analgesia Between Intravenous Paracetamol and Intranasal Tapentadol
The aim of the study was to compare the analgesic efficacy of intranasal tapentadol nasal spray 44.5mg and intravenous paracetamol 1gm during the postoperative period by Visual analog scale(VAS)in patients undergoing lower…
- Trial name
- NCT05999890
- Testing
- Tapentadol Hydrochloride
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Kempegowda Institute of Medical Sciences, Bangalore
SPINAL Fracture
Minimally Invasive Surgical Management of Traumatic Spinopelvic Instability
the main aim of this study is to evaluate the results of performing minimally invasive surgical management for cases with traumatic spinopelvic instability and spinopelvic dissociation.
- Trial name
- NCT05321186
- Testing
- minimally invasive spinopelvic fixation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Pain, Acute
SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator
Peripheral nerve block is an ideal choice for lower limb surgery because of the peripheral site of the surgical procedure and the ability to block pain pathways at multiple levels.
- Trial name
- NCT03450798
- Testing
- SOFT block group, spinal anesthesia group
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Ain Shams University
Postoperative Pain, Fracture Femur
Preoperative and Postoperative Comparison of Two Nerve Blocks in Intertrochanteric Fracture Surgery
Patients with intertrochanteric femur fractures experience significant perioperative and postoperative pain. Perioperative pain can complicate and prolong the anesthesia process for patients undergoing spinal anesthesia, leading…
- Trial name
- NCT07075432
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Erzincan University
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Femoral Fracture, Cognition Disorders
Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures
Spinal anesthesia blocks acute pain in older patients with femur fracture. Delirium is a common complication seen after femur fracture, affecting approximately 10-16% of patients.
- Conditions
- Femoral Fracture, Cognition Disorders, Cortisol; Hypersecretion
- Trial name
- NCT03856502
- Testing
- 8 mg of dexamethasone, 12,5 mg of 0,5 % of levobupivacaine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- General Hospital Sveti Duh
Osteoporosis, Fracture Risk Assessment
Five-Year CT Follow-Up of Vertebral Fracture Risk Using Opportunistic Osteoporosis Screening
This study evaluates whether opportunistic osteoporosis screening using routinely acquired computed tomography (CT) scans improves fracture risk prediction compared with guideline-recommended FRAX-based screening from age 50.
- Conditions
- Osteoporosis, Fracture Risk Assessment, Osteoporotic Fracture of Vertebra
- Trial name
- NCT07487688
- Testing
- Opportunistic osteoporosis screening
- Where
- Germany
- Volunteers
- 2,799 people
- Sponsor
- Technical University of Munich
Femur Fracture, Spinal Anesthesia
Echocardiography Examination Of The Cardiac Effects Of Different Regional Anesthesia Methods
Nerve blocks applied with neuraxial anesthesia and ultrasonography are used for many operations today. Neuraxial blocks cause varying degrees of decrease in the blood pressure level of the patients.
- Conditions
- Femur Fracture, Spinal Anesthesia, Lumbar Plexus Block
- Trial name
- NCT04975386
- Testing
- Transthoracic echocardiogram
- Volunteers
- 62 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Spinal Fractures, Osteoporosis
Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis.
- Trial name
- NCT00068822
- Testing
- Percutaneous vertebroplasty
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Mayo Clinic
SPINAL Fracture
Comparative Study of Balloon Kyphoplasty and Conservative Treatment
This study will compare two treatments in acute stable traumatic vertebral fractures (types A1, A2 and A3.1 in MAGERL Classification). The two treatments are the followings: 1.
- Trial name
- TRAUMAA1-2-3 (NCT00749242)
- Testing
- orthopedic brace, balloon kyphoplasty
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vertebral Body Fractures
Study on the Treatment of Osteoporotic Vertebral Fractures Using Vertebral Body Stenting
This is a randomized, controlled study to document and evaluate the clinical performance of the Vertebral Body Stenting (VBS) System in osteoporotic fractures of the thoracic and lumbar spine.
- Trial name
- NCT01847898
- Testing
- Vertebral Body Stenting (VBS), Balloon Kyphoplasty
- Where
- 5 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- Synthes GmbH
Osteoporosis, Hyperkyphosis
Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures
Multiple vertebral fragility fractures, one of the main complications of osteoporosis, are frequently associated with thoracic hyperkyphosis, which in turn leads to significant postural alterations.
- Conditions
- Osteoporosis, Hyperkyphosis, Vertebral Body Fracture
- Trial name
- NCT06842758
- Testing
- Rehabilitation Treatment, None Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Osteoporosis, Vertebral Fracture
Chiropractor Delivered Virtual Intervention After Vertebral frActure
This study will determine feasibility of a chiropractor delivered virtual intervention for individuals following osteoporotic vertebral fracture. This pilot trial will have two parallel groups with a 1:1 ratio.
- Trial name
- VIVA (NCT07288684)
- Testing
- VIVA
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Waterloo
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Osteoporosis, Vertebral Fracture
Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
In the present feasibility and pilot study we aim to investigate the effect and safety of patient education with or without additional physical training or mindfulness/medical yoga in patients with manifest spinal osteoporosis…
- Trial name
- NCT05227976
- Testing
- Patient education (Theory), Physical training, Mindfulness and medical yoga in group
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- University Hospital, Linkoeping
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Proximal Femur Fractures, Nerve Block Assessment
Comparison Of Preoperative Ultrasound Guided Fascia Iliaca Block Versus Femoral Nerve Block for Proximal Femur Fractures Before Positioning for Spinal Anaesthesia
Proximal femur fractures are among the most painful orthopedic injuries Adequate analgesia is essential to facilitate positioning for spinal anesthesia, reduce opioid requirements, and minimize related complications.
- Trial name
- NCT07716358
- Testing
- Femoral Nerve Block, Fascia Iliaca Nerve Block
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Sahara Medical College Narowal Pakistan
Vertebral Fracture, Balance
Evaluation of Balance and Gait Weight Distribution in Patients With Vertebral Column Fractures
Vertebral column fracture presents a significant warning of subsequent osteoporotic fracture and frequent falls. The presence of an osteoporotic vertebral fracture is also a predictor of further risk of vertebral and other…
- Conditions
- Vertebral Fracture, Balance, Gait, Unsteady
- Trial name
- NCT05010135
- Testing
- Zebris Gait System assessment for gait weight distribution + EMG evaluation of Quadriceps, Hamstrings, Tib Anterior and Calves + Positional Sense assessment
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Tung Wah College