Clinical trials: Spinal Induced Hypotension
Hypotension, Cesarean Section Complications
Maternal Care Bundle to Attenuate Hypotension in Cesarean Section
Cesarean Section (CS) is a common obstetric surgery that can be performed by both general or regional anaesthetic techniques. Hypotension is the most common complication of spinal anaesthesia, its incidence varying from 70% to 80…
- Trial name
- NCT05468125
- Testing
- guidance
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Suez Canal University
Spinal Anesthesia-induced Hypotension
Predicting if the Blood Pressure Will Drop After Spinal Anesthesia Using Ultrasound of the Neck
After a spinal injection, blood pressure might drop for a short time, similar to what happens with general anesthesia. This drop can be different for each person.
- Trial name
- NCT06711289
- Testing
- Carotid ultrasound measurement, Vital sign measurement, Spinal anesthesia
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Spinal Induced Hypotension, Old Age; Debility
Efficacy of Subclavian Vein/Artery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients
The hypothesis of the study will be that the subclavian vein/subclavian artery diameter (SCVD/SCAD) index will be a good predictor of spinal-induced hypotension in geriatric patients.
- Trial name
- NCT07286422
- Testing
- Assessment of the SCV & SCA, Assessment of the IVC and aorta
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Tanta University
Spinal Hypotension, Vasopressor
Caffeine and Prophylactic Noradrenaline Requirement During Cesarean Delivery
Spinal anesthesia is the preferred regional technique in obstetric practice because it provides high maternal satisfaction and eliminates the need for airway manipulation.
- Trial name
- NCT07655245
- Testing
- Caffeine (200 mg)
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Hypotension
Phenylephrine for Spinal Induced Hypotension
This study is designed to determine the ED90 for a single dose of phenylephrine for the treatment of spinal induced hypotension in parturients presenting for an elective CD.
- Trial name
- NCT00781157
- Testing
- Phenylephrine bolus
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- IWK Health Centre
Cerebral Hypoperfusion, Hypotension
The Effect of Controlled Hypotension
Controlled hypotension is currently used in spinal surgery to reduce bleeding at the surgical site, improve the surgeon's visibility, and decrease intraoperative blood loss.
- Trial name
- NIRS (NCT06928870)
- Testing
- MAP 55-65 mmHg, MAP 66-75 mmHg
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Hypotension During Surgery, Hypotension Drug-Induced
Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean Delivery
The goal of this randomized controlled trial is to compare for non inferiority for fetal wellbeing Hypotension Prediction Index - Guided Therapy and Continuous Norepinephrine Infusion in in the Prevention of Spinal…
- Trial name
- NCT05970770
- Testing
- Hypotension Prediction Index, Norepinephrine
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spinal Induced Hypotension
PVI for Prediction of Spinal Induced Hypotension
The hypothesis is that plethysmography variability index can predict the occurrence of hypotension after spinal anesthesia for cesarean delivery
- Trial name
- NCT01967914
- Testing
- PVI
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Spinal Induced Hypotension, Geriatric Population
Spinal-Induced Hypotension in Geriatric Patients
The study will be conducted to asses preoperative condition of venous system by VExUS score and it's relation with the incidence of spinal induced hypotension in geriatric patients undergoing surgery with spinal anaesthesia.
- Conditions
- Spinal Induced Hypotension, Geriatric Population, Intravascular Volume
- Trial name
- NCT05862298
- Testing
- venous excess ultrasound score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Many previous studies have investigated the ability of various methods such as passive leg raising test , and inferior vena cava collapsibility index in predicting post-spinal hypotension, but none of them have succeeded in…
- Trial name
- NCT05991063
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Assault by Hot Fluids
Warming IV Fluids and Incidence of Hypotension
This prospective, double-blinded, randomized, controlled study was undertaken to evaluate whether warming IV fluids (37 oC) resulted in lower incidence of hypotension, less ephedrine and transfusion requirement and lower fluid…
- Trial name
- NCT02582112
- Testing
- Active Comparator: Warming group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hakki Unlugenc
Hypotension
Preventing Hypotension in Parturients With an Elevated Body Mass Index (BMI)
Previous research regarding the use of phenylephrine has excluded obese subjects (BMI >35). This subgroup of patients represents a large portion of the obstetric patient population locally and nationally.
- Trial name
- NCT01481740
- Testing
- Phenylephrine bolus, phenylephrine infusion
- Where
- 2 sites in United States, Canada
- Volunteers
- 178 people
- Sponsor
- IWK Health Centre
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Spinal Anesthesia
Norepinephrine for Spinal-induced Hypotension
Norepinephrine (NE) infusion is used prophylactically to counteract the vasodilator effect of spinal anesthesia. prophylactic use of NE infusion is expected to decrease bouts of hypotension, vomiting and increase patient…
- Trial name
- NE in spianl (NCT03308708)
- Testing
- Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Outcome
Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on neonatal outcomes following cesarean section.
- Trial name
- NCT06151483
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Where
- China
- Volunteers
- 1,184 people
- Sponsor
- General Hospital of Ningxia Medical University
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension
Three different regimens of phenylephrine are being evaluated to see if one is superior over the other in the maintenance of cardiac output while keeping normotension and/or treating hypotension experienced when receiving spinal…
- Trial name
- NCT02101047
- Testing
- Phenylephrine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Frailty, Spinal Anesthesia
Frailty and Spinal Anesthesia-Induced Hypotension in Elderly
60 patients aged 65 and older with ASA I-III physical status undergoing elective surgery under spinal anesthesia will be included in the study.
- Trial name
- NCT06757439
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Adverse Effect
Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on maternal hemodynamics in preeclamptic patients following cesarean section.
- Trial name
- NCT06151444
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 160 people
- Sponsor
- General Hospital of Ningxia Medical University