Clinical trials: Spinal Instrumentation
Cervical Spondylosis
Clinical Evaluation for Digital Acupuncture Manipulation Therapeutic Instrument
The investigators design a randomized, control study to evaluate the therapeutic effect of digital acupuncture instrument in cervical spondylotic radiculopathy patients using the following outcomes: the Visual analogue…
- Trial name
- NCT04525651
- Testing
- Digital Acupuncture Manipulation Therapeutic Instrument, Manual Acupuncture
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Degenerative Scoliosis
Degenerative Scoliosis
Several deformities of the spine exist such as degenerative lumbar scoliosis. These deformities can generate functional discomfort and limit the patient's quality of life.
- Trial name
- DS (NCT05105737)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Pain, Post Operative Pain
Erector Spina Plane Block for Multilevel Major Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.
- Trial name
- NCT05983393
- Testing
- Erector spinae plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Degenerative Disc Disease
P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation
The aim of this trial is to evaluate if P-15L bone graft (investigational device) is not inferior in effectiveness and safety to local autologous bone (and allograft where necessary) as an extender (control device) when applied…
- Trial name
- NCT03438747
- Testing
- P-15L Bone Graft, Local autologous bone in a TLIF with Instrumentation
- Where
- 34 sites in United States
- Volunteers
- 290 people
- Sponsor
- CeraPedics, Inc
Spinal Cord Diseases
Patient Specific Template Guided Pedicle Instrumentation Versus Free Hand Technique
The clinically already tested and approved MySpine system is compared to the free-hand dorsal instrumentation, which is the gold standard in spondylodesis surgery.
- Trial name
- NCT03318692
- Testing
- spondylodesis, CT
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- Balgrist University Hospital
Scoliosis
Impact of the Choice of the Distal Vertebral in the Surgery of the Thoracic Adolescent Idiopathic Scoliosis
The problem of choosing the supporting vertebra was the subject of several studies. They do not suggest as regards the techniques that are not currently used or with insufficient setback.
- Trial name
- VD-SIA (NCT02791776)
- Testing
- Scoliosis
- Where
- 16 sites in France, Lebanon
- Volunteers
- 157 people
- Sponsor
- Fondation Lenval
Scoliosis
Shilla Growth Permitting Spinal Instrumentation System for Treatment of Scoliosis in the Immature Spine
The objective of this study is to retrospectively and prospectively review patients who have undergone this technique looking at age of the patient, magnitude of the curve preoperatively, postoperatively and over time, diagnosis…
- Trial name
- NCT00577226
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Thoracolumbar Spinal Fusion
Retrospective Evaluation of Upper Instrumented Vertebrae (UIV) Screw Loosening Following Spine Surgery
The REESE study is looking at information from past spine surgeries to learn how often screws placed at the top of a spinal fusion become loose over time.
- Trial name
- REESE (NCT07838571)
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Intervertebral Disk Degeneration
An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation
The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented anterior cervical discectomy and…
- Trial name
- NCT00310440
- Testing
- P-15 Synthetic osteoconductive bone substitute, Autologous bone
- Where
- 12 sites in United States, Canada
- Volunteers
- 319 people
- Sponsor
- CeraPedics, Inc
Degenerative Spondylolisthesis
SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis
This trial, conducted in adult patients with degenerative spondylolisthesis needing surgical treatment at one level, aimed at comparing two approaches of spinal fusion.
- Trial name
- SPONGIT (NCT00869882)
- Testing
- Circumferential arthrodesis, Posterolateral fusion with instrumentation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Degenerative Disc Disease, Spondylolisthesis
Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF)
This is a first-in-human, dose escalation clinical study to evaluate the feasibility, safety, and tolerability of 3 different doses of immunoselected, culture-expanded, nucleated, allogeneic MPCs (NeoFuse) when combined with…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT00549913
- Testing
- NeoFuse, posterolateral spinal fusion with instrumentation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mesoblast, Ltd.
Idiopathic Scoliosis
Scoliosis Surgery Using the PASS® LP System
The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the…
- Trial name
- NCT01019109
- Testing
- Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Medicrea, USA Corp.
Adaptive Sport in Spinal Cord Injury
Study About Acting of Adaptive Sport in Musculoskeletal, Cardiovascular System and the Quality of Life of Individuals With Spinal Cord Injury Through Biomedical Instrumentation
The hypothesis is to the fulfillment of canoeing, handbike and conventional physiotherapy activities the groups could show improvement in muscle strength of the arms, decreased resistance of the lower limbs (spasticity), improved…
- Trial name
- Adaptive sport (NCT02177929)
- Testing
- adapted canoeing, hadbike and conventional physiotherapy
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade do Vale do Paraíba
SPINAL Fracture
Calcium Phosphate Versus PMMA Cement in Thoracolumbar Fractures
Patients at the age of 50 or older presenting with thoracolumbar fractures including segments TH 6-L5 and A3/A4 fractures according to the AO Spine fracture classification after the acute trauma and planned surgery within 3 weeks…
- Trial name
- CaPvsPMMA (NCT04743869)
- Testing
- Kyphos FS™ Bone Substitute, KYPHON ActivOs® Bone Cement with Hydroxyapatite
- Volunteers
- 85 people
- Sponsor
- Medical University of Graz
Degenerative Disc Disease
TXA in Spinal Fusion
Tranexamic acid and placebo will be given during surgery to patients who have elected to undergo lumber interbody fusion on 2 or more levels.
- Trial name
- NCT04272606
- Testing
- Tranexamic Acid, Saline Solution, Visual Acuity Exam
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Catherine R. Olinger
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion
This study will describe postoperative pain management for spine surgery patients receiving liposomal bupivacaine (Exparel®) compared to patients not receiving the drug.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Spondylolisthesis
- Trial name
- NCT03745040
- Testing
- Liposomal bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Allina Health System
Spinal Deformity
Risk Factors for Proximal Junctional Kyphosis Assessment After Spinal Instrumentation
The surgical management of spinal deformities especially in adults is complex. The conventional surgical treatment of these deformations is a scope arthrodesis of the spine.
- Trial name
- CYPHORACHI (NCT02881580)
- Testing
- No intervention : descriptive study
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Failed Back Surgery Syndrome, Pain
Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome
The EVIDENCE trial is a randomized controlled trial comparing the therapeutic effectiveness and cost-effectiveness of the Precision® Spinal Cord Stimulation with that of reoperation as a treatment of pain in patients with Failed…
- Conditions
- Failed Back Surgery Syndrome, Pain, Back Pain
- Trial name
- Evidence (NCT01036529)
- Testing
- Precision Spinal Cord Stimulator, Back Surgery
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Degenerative Disc Disease, Spondylolisthesis
The European Robotic Spinal Instrumentation (EUROSPIN) Study
In a multinational prospective study, preoperative, intraoperative, perioperative and follow-up data on patients receiving thoracolumbar pedicle screw placement for degenerative disease or infections or tumors will be collected.
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis, Recurrent Disc Herniation
- Trial name
- EUROSPIN (NCT03398915)
- Testing
- Transpedicular Instrumentation
- Where
- 12 sites in Austria, France and 5 more
- Volunteers
- 932 people
- Sponsor
- Marc Schröder
Spinal Fusion
Spinal Fusions Steroid Study
Current efforts to improve pain alleviation focus on non-opioid pharmaceuticals. Intravenous perioperative corticosteroid administration has been suggested as an alternative method for post-operative pain control.
- Trial name
- SFSS (NCT05287035)
- Testing
- Dexamethasone injection, Saline injection
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Texas at Austin