Clinical trials: Spinal Nerve Root Disorder Nos
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Degenerative Disc Disease(DDD)
Evaluation of the Safety and Effectiveness of the CORUS™ Posterior Cervical Stabilization System 3D (PCSS 3D) for the Treatment of 2-level Cervical Degenerative Disease
The objective of this clinical trial is to evaluate the treatment of patients with two-level cervical degenerative disease using a combination of Anterior Cervical Discectomy and Fusion (ACDF) and Posterior Cervical Fusion (PCF)…
- Trial name
- SECOND (NCT07721493)
- Testing
- Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Providence Medical Technology, Inc.
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Cervical Radiculopathy
Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block
This study retrospectively analyzed medical records and imaging records (ultrasound images, fluoroscopy-guided images) of US-CSNRB and FL-CTFEB procedures performed at the Yangsan Pusan National University Hospital Pain Clinic…
- Trial name
- NCT07447271
- Testing
- ultrasound guided cervical selective nerve root block, fluoroscopy-guided cervical transforaminal epidural block
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Pusan National University Yangsan Hospital
Radiculopathy, Myelopathy
Post-Approval Clinical Trial of the PCM® Cervical Disc
On October 26, 2012, the FDA granted Premarket Approval (PMA) for the PCM Cervical Disc. PCM Cervical Disc is indicated for use in skeletally mature patients for reconstruction of a degenerated cervical disc at one level from…
- Trial name
- NCT01905930
- Testing
- PCM Cervical Disc, Anterior Cervical Discectomy and Fusion (ACDF)
- Where
- 18 sites in United States
- Volunteers
- 494 people
- Sponsor
- NuVasive
Low Back Pain, Mechanical, Spinal Stenosis
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine /…
- Conditions
- Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical
- Trial name
- Hypermoble (NCT02761928)
- Testing
- Beighton score for hypermobility
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The University of Texas Health Science Center, Houston
Lumbar Radiculopathy
Progressive Inhibition of Neuromuscular Structure and Neural Tissue Mobilization.
Lumbar radiculopathy is a neuromusculoskeletal condition that is characterized as radiating pain in the leg described as electric, burning, or sharp, and is associated with dermatomal or myotomal differences and tendon reflex…
- Trial name
- NCT07062705
- Testing
- Progressive Inhibition of Neuromuscular Structure, Neural Tissue Mobilization.
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Cervical Radiculopathy
The Effect of Dry Needling and Prolotherapy on Pain, Function, and Quality of Life in Patients With Cervical Radiculopathy.
Cervical radiculopathy is characterized by neurological dysfunction caused by compression and inflammation of the spinal nerves or nerve roots of the cervical spine.
- Trial name
- NCT06457529
- Testing
- conventional treatment with Prolotherapy, Dry Needling and conventional treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Superior University
Radiculopathy
The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery
The median Orthopaedic surgery wait time in Canada is 36.7 weeks (Esmail 2008), thus there is a need to find alternative treatments for pathologies such as lumbar disc herniations (LDH).
- Trial name
- NCT01073995
- Testing
- Kenalog and Sensorcaine
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Horizon Health Network
Pain, Disability
Caudal Epidural Steroid Injections for Low Back Pain/Sciatic Lumbar Pain
The study hypothesis is that caudal epidural steroid injections provides short term relief to patients with persistent low back pain and sciatica due degenerative disc disease or lumbar spinal stenosis.
- Trial name
- FIA1 (NCT01407913)
- Testing
- caudal epidural steroid injection
- Where
- Greece
- Volunteers
- 42 people
- Sponsor
- University of Ioannina
Cervicogenic Upper Extremity Radiculopathy
Transforaminal Versus Lateralized Interlaminar Cervical Epidurals
The purpose of this study is to compare two methods of giving epidural steroid injections for nerve pain in the arm that comes from the neck.
- Trial name
- NCT03389620
- Testing
- dexamethasone
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Duke University
Cervical Radiculopathy
Effects of Thoracic Mobility Versus Stretching Exercise Program in Patients of Cervical Radiculopathy
The study will be a randomized clinical trial with a sample size of 44 to determine the effects of thoracic mobility versus thoracic stretching exercises on pain, range of motion, and function in patients with cervical…
- Trial name
- NCT05404646
- Testing
- Thoracic mobility exercises with conventional physical therapy for cervical radiculopathy, Thoracic stretching exercises with conventional physical therapy for cervical radiculopathy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cervical Radiculopathy, Cervical Radicular Pain
Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck
Cervical Radiculopathy (CR) is an objective loss of sensory and/or motor function as a result of compression or irritation of the cervical spinal nerve root.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Neck Pain, Numbness
- Trial name
- NCT07375823
- Testing
- Exercise Therapy, Superimposition of electrical muscle stimulation on active movement
- Where
- Cyprus
- Volunteers
- 50 people
- Sponsor
- European University of Lefke
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Neck Pain, Spondylosis
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
The study is a prospective, first-in-human, multi-center, non-randomized, single-arm study to assess the safety and efficacy of the CEM-Cage used with the CEM-Plate in patients who are appropriate candidates for a 2-level…
- Conditions
- Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy
- Trial name
- NCT04883411
- Testing
- CEM-Plate Anterior Cervical Plating System and CEM-Cage Cervical Interbody System
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- ReVivo Medical, Corp.
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Arthritis, Tendonitis
Prospective Analgesic Compound Efficacy (PACE) Study
A 24-week observational prospective study on the efficacy of topical non-steroidal anti-inflammatory drugs for the relief of pain.
- Conditions
- Arthritis, Tendonitis, Gout, Radiculopathy
- Trial name
- PACE (NCT02403687)
- Testing
- baclofen 2%, Bupivacaine hydrochloride 1%, Cyclobenzaprine hydrochloride 2%
- Volunteers
- 300 people
- Sponsor
- Express Specialty Pharmacy
Sciatic Radiculopathy
Combined Rehabilitation With ALA, ALC, Resveratrol and Vitamin D in Discogenic Sciatica in Young People
The objective of this Interventional case-control clinical study is to evaluate the effectiveness of physiotherapy combined with the administration of Alpha Lipoic Acid, L-acetylcarnitine, Resvelatrol, Vit D3 in the treatment of…
- Trial name
- NCT06078163
- Testing
- supplementation, rehabilitation
- Where
- Italy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Cervical Radiculopathy, Cervical Disc Disease
Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery
The objective of this study is to perform a prospective, single-arm clinical evaluation utilizing the Spira™-C 3-D printed titanium interbody device for treatment of degenerative disc disease and spinal stenosis of the cervical…
- Trial name
- ACDF (NCT03786432)
- Testing
- Spira-C Interbody Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Corewell Health East