Clinical trials: Spinal Nerve Root Disorder Nos
Sciatica, Lumbar Radiculopathy
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments.
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease
- Trial name
- NCT04982965
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cervical Radiculopathy
Thoracic Manipulation in Patients With Cervical Radiculopathy
Hypothesis: The group of Cervical Radiculopathy patients receiving thoracic thrust manipulation will demonstrate immediate and short term significant clinically important changes in outcomes when compared to the sham manipulation…
- Trial name
- NCT01495728
- Testing
- Thrust Manipulation - Thoracic Spine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spine and Sport, Georgia
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Cervical Disc Disease, Cervical Radiculopathy
Rehabilitation After Anterior Cervical Discectomy and Fusion
Anterior cervical discectomy and fusion (ACDF) is a commonly performed surgical procedure for cervical disc herniation, cervical radiculopathy, and degenerative cervical spine disorders.
- Conditions
- Cervical Disc Disease, Cervical Radiculopathy, Postoperative Dysphagia
- Trial name
- ACDF-REHAB (NCT07814950)
- Testing
- Structured Postoperative Rehabilitation Program, Standard Postoperative Follow-up
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Sciatica, Lumbosacral Radiculopathy
Three CT Signs of Nerve-root Suffering in Low-back Sciatica: a Study of Their Frequency in Patients Referred for CT-guided Nerve-root Infiltration.
Retrospective, observational, single-centre study conducted at Nice University Hospital (Pasteur 2), Department of Diagnostic and Interventional Radiology.
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Low Back Pain
- Trial name
- NCT07690449
- Testing
- Pre-infiltration lumbar planning CT scan - reading of the three nerve-root signs
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Lumbar Disc Herniation With Radiculopathy, Sciatica
FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation
The FINDISC trial studies whether common back operation, microdiscectomy, is effective and safe for treating sciatica caused by a lumbar disc herniation.
- Trial name
- FINDISC-Pain (NCT07418944)
- Testing
- Microdiscectomy
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- Helsinki University Central Hospital
Cervical Radiculopathy
Effectiveness of Neck Isometric Exercises and Cervical Mobilization on Cervical Radiculopathy
Effectiveness of neck isometric exercises and cervical mobilization will be compared to observe the efficacy of these techniques on cervical radiculopathy
- Trial name
- NCT05884567
- Testing
- Isometric exercises, Mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Neuropathic Pain From Lumbosacral Radiculopathy
Extension Study to Evaluate the Long-Term Safety, Tolerability, and Maintenance of Effect of BIIB074
The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB074 in participants with neuropathic Pain From Lumbosacral Radiculopathy (PLSR).
- Trial name
- RELAY-1 Extend (NCT02957617)
- Testing
- BIIB074
- Where
- 51 sites in Austria, Belgium and 12 more
- Volunteers
- 302 people
- Sponsor
- Biogen
Pain, Neuropathic
Efficacy Study in Lumbosacral Radiculopathy
This study will be a double-blind, placebo-controlled, parallel group study. After enrolment and initial assessments, subjects will receive 35 days of study medication.
- Trial name
- NCT01110057
- Testing
- GS856553
- Where
- 17 sites in Denmark, France and 3 more
- Volunteers
- 142 people
- Sponsor
- GlaxoSmithKline
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Radiculopathy Lumbar, Disc Disease Lumbar
Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections
The purpose of this study is to compare the Microendoscopic combined with ultrasound technique to the standard routinely used X-ray guided transforaminal steroid injection technique.
- Trial name
- NCT05729022
- Testing
- Ultrasound microendoscopic technique, Fluoroscopy
- Where
- Lebanon
- Volunteers
- 124 people
- Sponsor
- American University of Beirut Medical Center
Myelopathy, Compressive, Radiculopathy, Cervical
Can Prophylactic Foraminotomy Prevent C5 Palsy
C5 palsy (C5P) is a well-known, although rare complication of cervical spine decompression surgery. In severe forms, C5P causes debilitating upper extremity weakness involving the deltoids and/or biceps brachii muscles…
- Conditions
- Myelopathy, Compressive, Radiculopathy, Cervical, C5 Palsy
- Trial name
- NCT03023696
- Testing
- Bilateral Cervical Keyhole Foraminotomy, Cervical Decompression
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- The Cleveland Clinic
Cervical Radiculopathy
Cervical Radiculopathy Trial
The primary aim of the present project is to compare the effectiveness of surgery and nonsurgical treatment in patients with cervical radiculopathy caused by either disc herniation or spondylosis.
- Trial name
- CRT (NCT03674619)
- Testing
- Anterior discectomy, Conservative treatment
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Radicular Pain Related to Lumbosacral Disc Disease
Milnacipran for Lumbosacral Radicular Pain
This study investigates whether milnacipran reduces radicular pain ("sciatica") in patients with lumbosacral disc disease.
- Trial name
- NCT01777581
- Testing
- Milnacipran
- Volunteers
- 13 people
- Sponsor
- Duke University
Endometriosis, Nerve Sheath Tumor
Learning Curve for the Visualization of Sacral Plexus on TVS
The purpose of this prospective study was to evaluate the learning curve of TVUS (transvaginal ultrasound) for the visualization of sacral nerve roots and sacral plexus on gynecological transvaginal ultrasound.
- Conditions
- Endometriosis, Nerve Sheath Tumor, Radiculopathy
- Trial name
- PlexUS (NCT06041347)
- Testing
- Transvaginal ultrasound
- Where
- Hungary
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Radiculitis
Comparison of Neural Mobilization Techniques to Standard Care Treatment in Patients With Lumbar Radiculitis
The purpose of this study is to determine the effectiveness of neural mobilization techniques compared to standard care treatment in patients with lumbar radiculitis.
- Trial name
- NCT02941133
- Testing
- Neural Mobilization, Standard Care
- Volunteers
- 130 people
- Sponsor
- Michalis Efstathiou
Discopathy, Herniated Cervical Disc
Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.
- Conditions
- Discopathy, Herniated Cervical Disc, Stenoses, Spinal, Radiculopathy
- Trial name
- PMCF_MOVE®-C (NCT05035693)
- Testing
- MOVE®-C
- Where
- 7 sites in Austria, Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NGMedical GmbH
Cervical Radiculopathy
Effects of Cervical Traction With and Without EMG Biofeedback in Patients With Cervical Radiculopathy
Cervical radiculopathy is a neurological condition which is caused by underlying musculoskeletal disorders including herniated disc and degenerative changes in cervical spine that results in narrowing or stenosis of…
- Trial name
- NCT05352464
- Testing
- cervical traction with EMG biofeedback, cervical traction and conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Radiculopathy, Cervical
Effect of Cervical Exercise Combined With Nerve Mobilization on Cervical Spondylotic Radiculopathy
The objective of this clinical trial was to investigate the effects of cervical spine exercises combined with nerve mobilization in patients with radiculopathy. The main questions it aims to answer are: 1.
- Trial name
- NCT06453798
- Testing
- cervical spine exercises, Neuromobilization
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Quanzheng Chen
Cervical, Cervical Radiculopathy
Comparison of Static and Dynamic Opening With Neural Sliding in Cervical Radiculopathy
The aim of this randomized controlled trial is to determine the effects of static and dynamic opening with neural sliding in patients with cervical radiculopathy for reducing pain, enhancing cervical range of motion and improve…
- Trial name
- NCT06154993
- Testing
- static opening with slider+ Conventional PT, dynamic opener with slider + Conventional PT
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University