Clinical trials: Spinal Pain Syndrome
Sciatica, Low Back Pain
Effects of Extension Biased External Limb Loading in Addition to McKenzie Extension Protocol in Lumbar Derangement Syndrome
Low back pain is one of the most common problem affecting one's daily living activities. McKenzie Method of Mechanical Diagnostic Therapy (MDT) is an appealing modality of treatment.
- Conditions
- Sciatica, Low Back Pain, Low Back Pain, Mechanical
- Trial name
- NCT04155450
- Testing
- Extension Biased External Limb Loading Exercises, McKenzie Extension Exercise Protocol, Moist Heat
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Failed Back Surgery Syndrome
StruCtuRal And FuncTional Brain Alterations by Conventional Spinal Cord Stimulation And High DensitY Stimulation
This study is an interventional prospective observatory single center trial, investigating the supraspinal effects of long term conventional SCS (60 Hz) and paresthesia-free high density SCS in failed back surgery syndrome (FBSS)…
- Trial name
- SCRATCHY (NCT02650349)
- Testing
- fMRI
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Universitair Ziekenhuis Brussel
Scoliosis Idiopathic Adolescent, Dysmenorrhea
Effect of Myofascial Release on Scoliotic Females With Dysmenorrhea.
PURPOSE: The purpose of this study is to determine the effect of myofascial release on spinal curvature, premenstrual symptoms, and quality of life in scoliotic females with dysmenorrhea
- Conditions
- Scoliosis Idiopathic Adolescent, Dysmenorrhea, Premenstrual Syndrome, Quality of Life
- Trial name
- NCT05817513
- Testing
- Myofascial release., Traditional exercises for scoliosis treatment.
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Failed Back Surgery Syndrome, Complex Regional Pain Syndrome (CRPS)
A Study to Confirm the Safety of High Frequency DRG Stimulator in Patients With Chronic Lower Limb Pain
This study is a prospective, single-arm, open label, single center pilot study to confirm the safety of a ultrahigh frequency DRG stimulator in patients with chronic lower limb pain. The actual trial length is 5 days.
- Trial name
- NCT03285113
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GiMer Medical
Chronic Fatigue Syndrome, Fibromyalgia
Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord
Chronic pain and fatigue are characterized by peripheral and central mechanisms including low pain thresholds, temporal summation, peripheral and central sensitization.
- Trial name
- NCT03075254
- Testing
- A Peltier for Sensory testing, functional magnetic resonance imaging for Brain Neuroimaging, fMRI for Spinal Cord Neuroimaging
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Florida
Failed Back Surgery Syndrome
STructural And FunCTional Brain Alterations by HIgh FrequenCy Spinal Cord Stimulation
This study is an interventional prospective observatory single center trial, investigating the supraspinal effects of long term paresthesia-free high frequency SCS in FBSS patients with back and leg pain completed with resting…
- Trial name
- TACTIC (NCT02650362)
- Testing
- fMRI
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pain, Intractable
Identification of Outcome Predictors and Stratification of Responder Profiles Implanted With Spinal Cord Stimulation. An AI-based-pathway & Algorithmic Approach to Treat Failed Back Surgery Syndrome Patients
Failed Back Surgery Syndrome is commonly defined as new, recurrent, or persistent pain in the back and/or leg(s) of at least 6-month duration following spinal surgery.
- Trial name
- PREDIBACK 2 (NCT04587674)
- Testing
- Spinal Cord Stimulation
- Where
- 7 sites in France
- Volunteers
- 110 people
- Sponsor
- Poitiers University Hospital
Complex Regional Pain Syndrome
Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome
To demonstrate that spinal cord stimulator has an effect on sympathetic function (the one that give us the fight and flight response).
- Trial name
- CRPS (NCT00780390)
- Testing
- Autonomic Function Assessment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Neck Pain, Neck Disorder
Effects of Different Health Qigong Routines on CS Among Chinese College Students
Health Qigong, originated from Chinese traditional guidance techniques, is known as China's "six major medical techniques" together with "stone breaking", "acupuncture and moxibustion", "massage", "medicine" and "walking on…
- Conditions
- Neck Pain, Neck Disorder, Cervical Spondylosis
- Trial name
- NCT06130982
- Testing
- Health Qigong·Yijinjing, Health Qigong·Wuqinxi, Health Qigong·Baduanjin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Universiti Putra Malaysia
Chronic Pain Syndrome, Multi Focal Pain
Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients with Cervical Lead Placement
This observational, prospective data collection is designed to evaluate the effectiveness and stimulation coverage of closed-loop spinal cord stimulation (CL-SCS) therapy in patients with cervical lead placement.
- Conditions
- Chronic Pain Syndrome, Multi Focal Pain, Failed Neck Surgery Syndrome, Polyneuropathies
- Trial name
- NCT06359561
- Testing
- cervical lead placement
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Rijnstate Hospital
Lumbar Osteoarthritis
Primary Osteoarthritis Lumbar Spine: Establishing Its Cause, Pathogenesis and Treatment.
The study was about a root cause of Primary Osteoarthritis Lumbar Spine producing disabilities in sitting, climbing and walking etc. In advance stage the person is bereft of his/her personal physical activities.
- Trial name
- NCT05693415
- Where
- 6 sites in India
- Volunteers
- 154 people
- Sponsor
- Knee Pain Clinic
Chronic Pain, Neuropathic Pain
Neuronal Activation Accuracy in Closed-loop Spinal Cord Stimulation
Observational, prospective, single-center to assess neuronal activation accuracy and stimulation sensation in patients with closed-loop spinal cord stimulation therapy.
- Conditions
- Chronic Pain, Neuropathic Pain, Persistent Spinal Pain Syndrome Type 2
- Trial name
- NAA (NCT06775535)
- Testing
- ECAP-controlled, closed-loop SCS
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Karel Hanssens
Temporomandibular Joint Dysfunction Syndrome
Temporomandibular Dysfunction in Patients With Cervical Disc Herniation
Cervical spine problems are associated with temporomandibular joint (TMJ) and related muscles.The aim of the present study was to investigate temporomandibular joint dysfunction (TMD) and pain in individuals with cervical disc…
- Trial name
- NCT06141863
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Pain, Intractable
OPTIONS Spinal Cord Stimulation Programming Parameters
The purpose of this study is to evaluate programming options in spinal cord stimulation for the management of chronic, intractable pain of the trunk and limbs.
- Trial name
- NCT02503787
- Testing
- Spinal Cord Stimulation (SCS)
- Where
- 11 sites in United States
- Volunteers
- 64 people
- Sponsor
- MedtronicNeuro
Failed Back Surgery Syndrome, Limb Ischemia
Evaluation of Online Tool (E-TOOL SCS) in Spinal Cord Stimulaion
This observational multicenter study aims to evaluate the reliability and validity of the e-tool for selecting patients eligible for SCS for chronic pain caused by one of the four etiologies listed above in the experience of…
- Conditions
- Failed Back Surgery Syndrome, Limb Ischemia, Neuropathic Pain, Complex Regional Pain Syndromes
- Trial name
- E-TOOLSCS (NCT06229015)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Failed Back Surgery Syndrome
Objective Data on Daily Activity in Patients Treated with SCS: the Intellis Study
In spinal cord stimulation (SCS), most outcome data are based on patient questionnaires. The lack of tools for objective evaluation of the effects of SCS on chronic pain has posed a barrier for providing solid proof of the…
- Trial name
- NCT04710355
- Testing
- Spinal cord stimulation
- Where
- 7 sites in Belgium, Denmark and 2 more
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Failed Back Surgery Syndrome
Subcutaneous Peripheral Nerve Stimulation (PNS) as "Hybrid Stimulation" After Failure of Spinal Cord Stimulation (SCS) to Control the Back Pain Component in Failed Back Surgery Syndrome (FBSS) Patients.(CUMPNS Study)
Despite globally favourable outcomes of Spinal Cord Stimulation (SCS), a significant proportion of Failed Back Surgery Syndrome (FBSS) patients do not obtain adequate coverage of low back pain.
- Trial name
- NCT02110888
- Testing
- Subcutaneous peripheral nerve stimulation, SCS Only
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Poitiers University Hospital
Shoulder Pain, Shoulder Impingement Syndrome
Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- NCT03167138
- Testing
- Autologous micro-fragmented adipose tissue, Lipogems system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Paraplegia, Spinal Cord Injuries
Natural History of Shoulder Pathology in Manual Wheelchair Users
Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pain that greatly affect quality of life and level…
- Conditions
- Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
- Trial name
- NHSSI (NCT02600910)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston