Clinical trials: Spinal Pain Syndrome
Failed Back Surgery Syndrome, SCS
Spinal Cord Stimulation Versus Instrumentation for FBSS
Low back pain affects people of all ages and has become the leading cause of living with disability worldwide. Patients, suffering from persistent pain after spinal surgery in the absence of any clear spinal pathology are defined…
- Conditions
- Failed Back Surgery Syndrome, SCS, Neuromodulation, Spinal Cord Stimulation
- Trial name
- PROMISE (NCT05466110)
- Testing
- Spinal Cord Stimulation, Spinal Fusion Surgery
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- University Hospital Augsburg
Rheumatic Diseases, Lupus Erythematosus, Systemic
Pain Phenotyping of Rheumatic Diseases - An Observational Study
Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and change nerve signals in the brain.
- Conditions
- Rheumatic Diseases, Lupus Erythematosus, Systemic, Lupus Vasculitis, Central Nervous System, Arthritis
- Trial name
- NCT07829497
- Testing
- Bedside quantitative sensory testing
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Pain, Postoperative, Neuropathic Pain
Midline Versus Dorsolateral Spinal Cord Stimulation for Post-surgical Neuropathic Pain
The goal of this interventional study is to learn if dorsolateral spinal cord stimulation (DL-SCS) can treat focal post-surgical, medically refractory neuropathic pain.
- Trial name
- MIDL-SCS (NCT06390150)
- Testing
- Spinal Cord Stimulator
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle: Phase II
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05459324
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Albany Medical College
Spinal Cord Injuries, Pain
Manual Therapy for the Treatment of Shoulder Pain for Overuse Syndrome Wheelchair Dependent Persons
Shoulder pain is a common, debilitating problem for persons with Spinal cord injuries (SCI). Shoulder pain affects approximately 40-50% of the total population of persons with paraplegia (those with SCI with full use of their…
- Conditions
- Spinal Cord Injuries, Pain, Musculoskeletal Manipulations
- Trial name
- MTX (NCT04991415)
- Testing
- Manual Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Craig Hospital
Spinal Cord Injuries, Myofascial Pain Syndrome
Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Shoulder pain in people with spinal cord injury is one of the most prevalent in acute and chronic patients because of weakness in shoulder periarticular muscles, and also because of overuse of these part of the body in assistive…
- Conditions
- Spinal Cord Injuries, Myofascial Pain Syndrome, Shoulder Pain, Puncture
- Trial name
- NCT03709797
- Testing
- Dry needling in infraspinatus muscle
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Shoulder Pain, Rotator Cuff Tendinitis
Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury
Shoulder pain is common in persons with spinal cord injury (SCI). It is most often caused by overuse injuries to the muscles and tendons that can occur during wheelchair propulsion, transfers, and other activities of daily…
- Conditions
- Shoulder Pain, Rotator Cuff Tendinitis, Rotator Cuff Syndrome, Spinal Cord Injury
- Trial name
- NCT01355549
- Testing
- Platelet-rich plasma (PRP) therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Pain, Myofacial, Pain, Neck
Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Herniation?
Chronic neck pain is among the most frequently seen chronic painful conditions. As an important cause of disability, chronic neck pain is a musculoskeletal disorder that negatively affects quality of life.
- Conditions
- Pain, Myofacial, Pain, Neck, Pain, Chronic
- Trial name
- NCT04914637
- Testing
- Cervical interlaminar epidural steroid injection, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Temporomandibular Joint Dysfunction Syndrome
Dry Needling and Spinal Manipulation vs. Interocclusal Appliance (Splint), NSAIDs and Joint Mobs for Temporomandibular Dysfunction
The purpose of this research is to compare two different approaches for treating patients with temporomandibular dysfunction (TMD): Dry needling and spinal manipulation or Interocclusal Appliance (Splint), NSAIDs and…
- Trial name
- NCT03409874
- Testing
- Dry Needling, Spinal manipulation, Interocclusal Appliance
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Facet Joint Pain
Multimodal PT With and Without Proprioceptive Training in Lumber FJS
This will be a randomized clinical trial. The study will be conducted at Pakistan Railways General Hospital Rawalpindi and Riphah International Hospital Islamabad. Patients with FJS will be included.
- Trial name
- NCT05931653
- Testing
- Multimodal Physical therapy, Proprioceptive training along with and Multimodal Physical therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Pain, Healthy
Predicting Central Pain Among People With a Spinal Cord Injury by Evaluating Mechanisms Regulating Pain and Efficacy Testing of the TENS Apparatus
People with a Spinal Cord Injury can develop chronic pain within months of the injury. Up to 80% of the patients will develop chronic pain called "central pain" and describe the pain as: burning, stabbing, or "like electricity."…
- Trial name
- NCT01726881
- Testing
- Thermal stimulation, Mechanical stimulation, Transcutaneous Electrical Nerve Stimulator (TENS)
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Pain, Spinal Cord Injury
Deep rTMS in Central Neuropathic Pain Syndromes
Pain affects up to 30% of the general population. In particular, neuropathic pain (NeP) is caused by lesion or desease affecting peripheral or central somatosensory pathways and affects 7% of the adult population.
- Conditions
- Pain, Spinal Cord Injury, Post Stroke Pain
- Trial name
- DRTMS (NCT01932905)
- Testing
- deep rTMS
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Fibromyalgia, Manual Therapies
Effects of Manual Therapy in Fibromyalgia Syndrome
Fibromyalgia syndrome (FMS) is among the most difficult diseases that restrict physical functions of patients due to persistent aches,sleep problems,psychological problems and decrease the quality of life.
- Trial name
- Fibromyalgia (NCT03630757)
- Testing
- Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Bilgi University
Failed Back Surgery Syndrome
Effective Connectivity in Patients Receiving Spinal Cord Stimulation: an fMRI and EEG Dynamic Causal Modeling Study
In this study, a retrospective analysis will be performed on collected data of 14 patients with Failed Back Surgery Syndrome, treated with Spinal cord stimulation.
- Trial name
- CRIME (NCT03626428)
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- Moens Maarten
Postpoliomyelitis Syndrome
A Randomized, Double Blind, Placebo Controlled Trial L-carnitine and Piracetam in the Treatment of Weakness, Muscle Fatigue and Muscle Pain in the Postpoliomyelitis Syndrome
This protocol aims to assess of L-carnitine and piracetam to relieve weakness, muscle fatigue and muscle pain in patients with Postpoliomyelitis Syndrome.
- Trial name
- NCT01549847
- Testing
- L-carnitine and piracetam
- Where
- Brazil
- Sponsor
- Biolab Sanus Farmaceutica
Back Pain, Spinal Cord Stimulation
Efficacy of Spinal Cord Stimulation in Patients With a Failed Back Surgery Syndrome.
When patients suffer from chronic pain after multiple back surgeries, this is denominated as the 'failed back surgery syndrome'. A possible treatment for these patients is spinal cord stimulation.
- Trial name
- HDS (NCT03462147)
- Testing
- Spinal cord stimulation
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- Ziekenhuis Oost-Limburg
Low Back Pain, Failed Back Surgery Syndrome
Subcutaneous Stimulation as Add on Therapy to SCS toTreat Low Back Pain in FBSS
Aim of the study Failed back surgery syndrome (FBSS) is a clinical entity consisting of chronic leg and /or back pain due to radicular nerve damage.
- Conditions
- Low Back Pain, Failed Back Surgery Syndrome, Neuropathic Pain
- Trial name
- SubQ (NCT01776749)
- Testing
- SubQ
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- SubQ