Clinical trials: Spinal Radiculopathy
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Radiculopathy, Cervical, Myelopathy
A Study of Korean Society of Spine Surgery on the Outcomes of Anterior Cervical Discectomy and Fusion
The purpose of this study is firstly to determine the efficacy of cervical plate for anterior cervical discectomy and fusion using cervical cage, and secondly to investigate the determining factors for surgical outcomes.
- Trial name
- NCT01911013
- Testing
- anterior cervical discectomy and fusion, Cage and Plate, Cage alone
- Where
- 31 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Spinal Fusion, Radiculopathy Lumbar
SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study
The purpose of the study is to evaluate the safety and tolerability of DRG stimulation when placing a neurostimulator during the same procedure as implantation of spinal fixation with or without interbody cage systems in patients…
- Conditions
- Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT04054401
- Testing
- DRG Neurostimulation with Spinal Fusion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- SynerFuse, Inc
Radiculopathy, Myelopathy
RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery
A Prospective, open label, multi-center observational study of patients requiring surgical treatment at one or two (contiguous) cervical spine levels.
- Conditions
- Radiculopathy, Myelopathy, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- NCT02403453
- Testing
- Rhine Cervical Disc
- Volunteers
- 68 people
- Sponsor
- K2M, Inc.
Back Pain, Radiculopathy Lumbar
Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy
SNRB, as measured by the change in pain and objective functional ability, can solicit crucial information regarding a patient's clinical picture and can predict a patient's outcome post-surgery.
- Conditions
- Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
- Trial name
- NCT03801356
- Testing
- Selective Nerve Root Block
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Cleveland Clinic
Neuropathic Pain, Nociceptive Pain
PET/MRI in the Diagnosis of Chronic Pain
Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain.
- Conditions
- Neuropathic Pain, Nociceptive Pain, Mixed Pain (Nociceptive and Neuropathic), Spinal Pain
- Trial name
- NCT03556137
- Testing
- [18F]FTC-146
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lumbar Radiculopathy, Lumbar Spinal Stenosis
The Impact of Contrast Media Used in Epidural Steroid Injections on Thyroid Function Tests
This study is aim to disclose the effect of contrast media, which used in epidural steroid injections, on the parameters of thyroid function tests (TFTs). The patients who underwent an epidural steroid injection were included.
- Conditions
- Lumbar Radiculopathy, Lumbar Spinal Stenosis, Cervical Radiculopathy, Cervical Stenosis
- Trial name
- NCT05404412
- Testing
- Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Marmara University
Cervical Myelopathy, Cervical Radiculopathy
Long-term Follow-up Motion Analysis of ACD Versus ACDA
Rationale: Cervical degenerative disc disease (CDDD) is a common cause of cervical radiculopathy, myelopathy or myeloradiculopathy.
- Conditions
- Cervical Myelopathy, Cervical Radiculopathy, Spinal Stenosis, Spinal Disease
- Trial name
- NCT04545983
- Testing
- Motion Analysis
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Zuyderland Medisch Centrum
Posterior Cervical Spinal Surgery, Myelopathy Cervical
Cervical Orthosis Versus no Orthosis Following Multi-level Posterior Cervical Fusion
Use of cervical orthosis after instrumented posterior cervical spinal surgery is still widely practiced even though modern fusion techniques likely do not require additional stabilization from an external orthosis.
- Conditions
- Posterior Cervical Spinal Surgery, Myelopathy Cervical, Radiculopathy, Cervical, Spinal Stenosis Cervical
- Trial name
- NCT04308122
- Testing
- Cervical Orthosis (CO), No Orthosis
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Christopher Bailey
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury, Spinal Cord Injuries
MR Guided Focused Ultrasound for Treatment of Neuropathic Pain
Neuropathic pain is often a result of direct diseases of peripheral or central nervous system with an estimated prevalence of 8% of adults and this pain is associated with significant consequences because of longer symptom…
- Conditions
- Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury, Spinal Cord Injuries, Phantom Limb Pain
- Trial name
- NCT03111277
- Testing
- Experimental: ExAblate Transcranial treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Radiculopathy, Lumbar Disc Herniation
The Effect of Combination of Ultrasound and Flouroscopy Guidance in Caudal Epidural Injections
The primary purpose of this study is to asses the effect of caudal epidural injection guided by a combination of ultrasound and fluoroscopy on the duration of the procedure and the amount of radiation exposed during the…
- Conditions
- Radiculopathy, Lumbar Disc Herniation, Spinal Stenosis
- Trial name
- NCT05145842
- Testing
- floroscopy, ultrasound+fluoroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Radiculopathy, Central Spinal Stenosis
The Efficacy of Continuous Cold-Therapy on Postoperative Pain and Narcotics Use Following Spinal Fusion
Patient outcomes and satisfaction are an ever-increasing priority in surgical specialties. Cryotherapy has been utilized following spine surgery as an adjunct therapy to reduce postoperative inflammation and improve patient…
- Conditions
- Radiculopathy, Central Spinal Stenosis, Foraminal Stenosis, Herniated Nucleus Pulposus
- Trial name
- NCT03640338
- Testing
- Cold-Therapy System
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Stenosis, Herniated Nucleus Pulposus
Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
Neural injury is a well-known complication following extreme lateral lumbar interbody fusion (XLIF). It has been found that up to 9.4% of patients will have either temporary or persistent neurologic deficit.
- Conditions
- Stenosis, Herniated Nucleus Pulposus, Degenerative Disc Disease, Spondylosis
- Trial name
- NCT03327272
- Testing
- Methylprednisolone, Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Low Back Pain, Mechanical, Spinal Stenosis
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine /…
- Conditions
- Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical
- Trial name
- Hypermoble (NCT02761928)
- Testing
- Beighton score for hypermobility
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The University of Texas Health Science Center, Houston
Low Back Pain, Disc Disease
Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs
Intradiscal delivery of bone marrow concentrate (BMC) into discs, facet, epidural space, and sacroiliac joints
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Arthropathy Vertebrae
- Trial name
- NCT04559295
- Testing
- Bone Marrow Concentrate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stem Cures
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb
Cost Effectiveness of OMT for Chronic Low Back Pain
The specific aim of this study is to conduct a prospective, multicenter cohort study over four months to compare the cost of standard of allopathic care (control group, N=90) versus standard of care plus osteopathic manipulative…
- Conditions
- Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis
- Trial name
- NCT03532230
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rowan University
Spinal Stenosis, Lumbosacral Spondylosis
A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection
The purpose of this study is to determine the effects of different rates of Caudal Epidural Steroid Injection (CESI) on clinical outcomes of the patients.
- Conditions
- Spinal Stenosis, Lumbosacral Spondylosis, Radiculopathy
- Trial name
- NCT02939482
- Testing
- Triamcinolone Acetonide and normal saline solution
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Navamindradhiraj University
Cervical Radiculopathy, Cervical Spinal Fusion
FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC®
Cervical degenerative disease is an almost universal concomitant of human aging. Over half of the middle aged population has cervical spondylosis.
- Conditions
- Cervical Radiculopathy, Cervical Spinal Fusion, Cervical Myelopathy
- Trial name
- NCT03950349
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims