Clinical trials: Spine, Open
Neural Tube Defects - Spina Bifida and Anencephaly
Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification
The aim of this study is to examine whether the same total daily dosage of folic acid, when taken as a single daily dose or as multiple divided doses throughout the day, results in different blood folate and homocysteine levels…
- Trial name
- NCT00207558
- Testing
- folic acid
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cerebral Palsy, Down Syndrome
Investigation of Parents' Anxiety Level and Health Related Quality of Life in Different Types of Physical Disabilities
Disability brings many psychosocial problems in society. The effects of the health of a disabled child on the psychological health and quality of life of the family are inevitable.
- Conditions
- Cerebral Palsy, Down Syndrome, Spina Bifida, Muscular Dystrophy
- Trial name
- NCT04035967
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Sanko University
Meningomyelocele, Spinal Dysraphism
Management of Myelomeningocele Study (MOMS)
Spina bifida (myelomeningocele) is a complex birth defect in which a portion of the spinal cord is not fully developed. The overlying bones and skin are incompletely formed and the underdeveloped area of the spinal cord is…
- Trial name
- MOMS (NCT00060606)
- Testing
- Prenatal Myelomeningocele Repair Surgery, Postnatal Myelomeningocele Repair Surgery
- Where
- 3 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Spina Bifida, Sensory Disorder
Sensory and Motor Proficiency For Children With Spina Bifida
Spina bifida is one of the neural tube defects that cause neuromuscular dysfunction. Spina bifida is a disease accompanied by motor paralysis, musculoskeletal problems, Arnold-Chiari malformation, osteoporosis, hydrocephalus…
- Conditions
- Spina Bifida, Sensory Disorder, Motor Disorders, Upper Extremity Dysfunction
- Trial name
- NCT05318677
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Degenerative Lumbar Canal Stenosis
Comparison Between The Results of Open and Microsurgical Decompression in Degenerative Spinal Canal Stenosis in Lumbar Spine
To compare the outcomes of open and microsururgical decompression in degenerative spinal stenosis in lumbar spine
- Trial name
- NCT06722859
- Testing
- Open surgical decompression in degenerative lumbar canal stenosis, Microsurgical decompression
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spina Bifida
Fecal Microbium Change in Pediatric Patients With Spina Bifida: Prospective Case-control Study
Purpose: In order to verify the hypothesis that the composition of intestinal microbiota in children with spina bifida is different from that of normal control, prospective comparative analysis would be performed.
- Trial name
- NCT04186130
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Spina Bifida
The Study Aims to Improve the Accuracy of Detecting Spina Bifida During Early Ultrasound Scans. to Achieve This, an AI Model Has Been Developed to Provide Feedback About the Presence of Spina Bifida. a RCT Has Been Designed to Compare the Effectiveness of AI Feedback with No AI Feedback.
The study aims to improve the accuracy of detecting spina bifida during early ultrasound scans. To achieve this, an AI model has been developed to provide feedback about the presence of spina bifida.
- Trial name
- NCT06566014
- Testing
- Evaluation of XAI-assisted spina bifida diagnosis
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Spina Bifida
QUALAS Validation in Dutch
Rationale Patients with spina bifida often experience a decreased quality of life compared to patients without spina bifida. The Quality of Life Assessment for Spina Bifida (QUALAS) is a validated questionnaire to assess the…
- Trial name
- NCT06723951
- Testing
- QUALAS survey
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Folate Deficiency, Neural Tube Defects
Folic Acid Salt Study (FISFA Zambia)
Question: How effective is fortified iodized salt with folic acid (FISFA) in increasing serum and red blood cell folate in non-lactating, non-pregnant women of reproductive age in the country of Zambia who do not have active food…
- Trial name
- NCT06734611
- Testing
- Fortified Iodized Salt with Folic Acid (FISFA)
- Where
- 2 sites in United States, Zambia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neurogenic Bladder, Myelomeningocele
Can Dynamic Ultrasonography Replace Urodynamics in Follow-up of Patients With Myelomeningocele
Patients with neurogenic bladder need periodic evaluation with urodynamic study, a invasive and uncomfortable procedure. Aim: To evaluate the accuracy of dynamic ultrasonography as a feasible and noninvasive alternative…
- Trial name
- NCT03550898
- Testing
- Dynamic Ultrasonography
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Intermittent Urethral Catheterization, Spinal Dysraphism
The Effect of Nursing Interventions for Clean Intermittent Catheterization Caregivers and Child
In neurogenic or non-neurogenic bladder disorders, the removal process after the catheter is inserted into the bladder and the urine has been drained is called Clean intermittent catheterization (CIC).
- Conditions
- Intermittent Urethral Catheterization, Spinal Dysraphism, Urinary Tract Infections
- Trial name
- NCT04763382
- Testing
- experimental group: Training of caregivers, Control gruop
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Spina Bifida
Evaluation of Depression and Anxiety Levels of Parents of Children with Spina Bifida
Studies in the literature have measured the anxiety and depression levels of parents of children with spina bifida. Additionally, it has been reported that parents of children with non-neurogenic lower urinary tract dysfunction…
- Trial name
- NCT06802770
- Testing
- Anxiety, Depression levels
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Surgical Blood Loss, Spinal Surgery
Efficacy of Suction Enabled Retraction Device
This is a prospective randomized controlled trial of the Suction-Integrated Surgical Tissue Elevator \& Retractor [SISTER] device to assess: Effects on operative time and efficiency of exposure in open lumbar spine cases.
- Trial name
- NCT03160170
- Testing
- SISTER device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Children, Mobility Limitation
Parental Perspectives of Using Toy Cars on Social Interactions of Preschool Children With Mobility Impairments
The purpose of this study is to investigate parental attitudes towards their child who has a mobility impairment, to using a modified electric toy car, and to evaluate from their perspective, if it facilitated social interaction…
- Conditions
- Children, Mobility Limitation, Spina Bifida, Attitude to Health
- Trial name
- NCT02682043
- Testing
- Toy car
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postoperative Pain, Erector Spinae Plane Block in Spinal Surgery
Open Technique Erector Spinae Plane Block in Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.ESPB has been successfully applied as a part of multimodal analgesia in treating postoperative pain…
- Trial name
- NCT06157762
- Testing
- Erector spinae plane block, Erector spinae plane block performed by surgeon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Premature Infants, Cerebral Palsy
Interrater Reliability of Infant Motor Profile
The aim of this study is to assess risky infants (or diagnosed infants) with Infant Motor Profile, and analyze interrater and intrarater reliability of this test.
- Conditions
- Premature Infants, Cerebral Palsy, Down Syndrome, Metabolic Disorders
- Trial name
- IMP (NCT03188107)
- Testing
- Video based assessment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital