Clinical trials: Spine Fusion
Back Pain, Fusion of Spine, Lumbar Region
The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
The postoperative pain of lumbar fusion surgery is very severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Conditions
- Back Pain, Fusion of Spine, Lumbar Region, Spinal Stenosis
- Trial name
- NCT03047044
- Testing
- Optimizing basal infusion (B.I), Conventional PCA mode
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Arthritis Knee, Spine Fusion
Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery
The present study is a multi-center randomized prospective non-inferiority trial. The study's primary objective is to compare the coagulation profile upon using two different TXA administration strategies: empirical TXA…
- Conditions
- Arthritis Knee, Spine Fusion, Prostate Cancer, Arthritis of Hip
- Trial name
- NCT05957822
- Testing
- TXA, TEG6
- Where
- South Korea
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Pain, Postoperative
Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery
The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.
- Trial name
- NCT04749095
- Testing
- Erector spinae plane block
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
Spine Fusion, Spine Surgery
Fusion Status After ACDF
Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF).
- Trial name
- NCT05986006
- Testing
- Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft, Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stenosis, Fusion of Spine (Disease)
Anterior Bridging Cage With Bone Substitute Versus Localized Autobone in Transforaminal Lumbar Interbody Arthrodesis
The purpose of this study is to evaluation for the pattern of bone bridging of patients who undergo transforaminal lumbar interbody arthrodesis, the investigators hypothesize that auto local bone mixed with β-calcium phosphate +…
- Trial name
- NCT02485574
- Testing
- transforaminal lumbar interbody arthrodesis
- Where
- South Korea
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zenoss Co, Ltd
Degenerative Spine Diseases
Minimal Invasive Transforaminal Lumbar Interbody Fusion for Degenerative Lumbar and Lumbosacral Spine Diseases
The aim of this study is to evaluate clinical and surgical outcome of MI-TLIF for degenerative lumbar and lumbosacral spine diseases.
- Trial name
- NCT06545032
- Testing
- lumbar fusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Low Back Disorder
MMG vs. EMG for Cortical Breach Detection
The purpose of this study is to determine how well mechanomyography (MMG) and electromyography (EMG) prevent cortical bone breaches, or the pinching of a nerve from screw placement, in patients having lower back surgery requiring…
- Trial name
- NCT05352048
- Testing
- Triggered Electromyography, Mechanomyography
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Francis Farhadi
Spine Fusion, Surgery
Postoperative subQ Pain Control for Spinal Fusion Surgery
Post-operative pain following lumbar spine fusion is frequently difficult to manage and can lead to increased doses of opiate pain medications to control pain.
- Conditions
- Spine Fusion, Surgery, Pain, Postoperative
- Trial name
- NCT03476811
- Testing
- 0.25% Marcaine at 2ml/hr and pain medications, Placement of OnQ Drug pump
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Lumbar Spondylolisthesis Involving L4-L5, Lumbar Spondylolisthesis Involving L5-S1
Evidence For Fusion In Spine With Orthoss®
This study aims to evaluate the performance and safety of the Orthoss® as a bone graft extender in lumbar spondylodesis involving 1-2 levels (L4-L5 and/or L5-S1).
- Conditions
- Lumbar Spondylolisthesis Involving L4-L5, Lumbar Spondylolisthesis Involving L5-S1, Lumbar Spinal Stenosis, Lumbar Disc Degeneration
- Trial name
- EFFISO (NCT03853356)
- Testing
- Orthoss
- Where
- 3 sites in Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Geistlich Pharma AG
Spine Fusion
Steroids After Spine Fusion Surgery
This trial studies how well low-dose postoperative corticosteroids (FDA approved) affect patient outcomes (patient reported outcomes, pain medication use, length of stay, major complications, and time to first bowel movement)…
- Trial name
- NCT04568837
- Testing
- Prednisone 20 Mg
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multimodal Analgesic Approach
IV vs Oral Acetaminophen in Spine Fusion Perioperative Care
The United States is currently experiencing an explosive opioid epidemic. In 2014 alone, 28,647 Americans died from an opioid associated overdose; the annual death toll has increased by over 300% since 2000.
- Trial name
- NCT03020875
- Testing
- Ofirmev, Per Os Acetaminophen
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Physical Capability Outcomes
Physical Capability Outcomes After Single-Level PD-L vs Single-Level ALIF: a Multi-Center Clinical Trial
The purpose of this study is to compare the physical capability outcomes of patients who undergo single-level ProDisc-L disc replacement with those of patients who undergo stand-alone, single-level anterior lumbar interbody…
- Trial name
- NCT01055574
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery.
- Trial name
- NCT05019222
- Testing
- Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Enhanced Recovery After Surgery, Spine Surgery
Enhanced Recovery After Spine Surgery
Enhanced recovery pathways (ERP) after surgery have been shown to decrease length of stay and perioperative complications in a range of surgical specialties.
- Trial name
- NCT02949518
- Testing
- Enhanced Recovery Pathway (ERP) for Spine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Spinal Fusion Acquired, Fusion of Spine (Disease)
Efficacy and Safety of SurgiFill™ on Spinal Fusion
This study was designed to investigate the safety and efficacy of SurgiFill™, a bone grafting material, in patients with spinal fusion.
- Trial name
- NCT02466048
- Testing
- Spinal Fusion, SurgiFill™
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Dysphagia
Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative…
- Trial name
- NCT03677310
- Testing
- 3% Sodium Chloride, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Spinal Fusion, Spinal Stenosis
Spine Registration Using 3D Scanning
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
- Conditions
- Spinal Fusion, Spinal Stenosis, Scoliosis, Spondylolisthesis
- Trial name
- NCT05195580
- Testing
- Optical 3D Scanner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Advanced Scanners Inc.