Clinical trials: Spine Instability
Low Back Pain
Investigation of Lumbo-sacral Instability Using Custom Made Table - a Pilot Study
The aim of the study is to evaluate the feasibility and validity of conventional radiographs of the lumbo-sacral spine when the patient is lying on a special table which facilitates maximal lumbo-sacral flexion.
- Trial name
- NCT01600417
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Degenerative Disc Disease, Degenerative Spondylolisthesis
Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability
The purpose of this open, multi-center study is to prospectively collect outcome data on patients who are having lumbar spinal fusion surgery with implantation of the SpineLink® system.
- Trial name
- NCT00726310
- Testing
- SpineLink® , SpineLink® II
- Where
- 2 sites in United States
- Volunteers
- 202 people
- Sponsor
- Zimmer Biomet
Hypomotility, Lumbar Spine Instability
Lumbar Manipulation in Lumbar Hypomobility
The purpose of the study is to compare the immediate effects of thrust versus non-thrust lumbar manipulation in individuals with lumbar hypo-mobility on lumbar range of motion and springing force tolerance.
- Trial name
- NCT04521244
- Testing
- Thrust joint lumbar manipulation, Lumbar mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Down Syndrome, Cervical Spine Instability in Down Syndrome
Cervical Spine Abnormalities in Down Syndrome
The study aims to determine the prevalence,clinical presentations and radiographic cervical spine abnormalities associated Down syndrome in children at sohag university hospital
- Trial name
- NCT07260136
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Post Operative Pain, Cervical Spine Instability
Inter-semispinal Plane Block and Cervical Spine Surgery
The inter-semispinal plane (ISP) block is a novel ultrasound-guided technique that involves local anesthetic injection into the fascial plane between the semispinalis cervicis and semispinalis capitis muscles with subsequent…
- Trial name
- ISPB (NCT06003933)
- Testing
- Bupivacaine Hydrochloride, Lidocaine Hydrochloride, Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Yasser S Mostafa, MD
Lumbar Spinal Stenosis, Lumbar Spinal Instability
Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients
Patients presenting for lumbar spine surgery experience pain related to their spine condition. Following surgery, these patients also experience surgical pain resulting from disruption of skin, muscle tissue, vertebrae…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spinal Instability, Lumbar Spine Degeneration
- Trial name
- IPaRO (NCT03088306)
- Testing
- Standard analgesia use [Oxygen], Standard analgesia use [Hydromorphone], Standard analgesia use [Volatile Anesthesia]
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Johns Hopkins University
Degenerative Spine, Degeneration of Lumbar Intervertebral Disc
Percutaneous Trans-facet Spine Fixation
Percutaneous Trans-facet Fixation Massoud-Goel Technique and Theory for Treatment of Degenerative Spine
- Conditions
- Degenerative Spine, Degeneration of Lumbar Intervertebral Disc, Degenerative Cervical Disc Disease, Ligamentum Flavum Hypertrophy
- Trial name
- Massoud-Goel (NCT07001969)
- Testing
- Massoud-Goel Technique and Theory, Percutaneous Trans-facet Fixation for Treatment of Degenerative Spine
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mahmoud Massoud
Hemodynamic Instability
Effect of Remimazolam and Propofol on Hemodynamic Stability in Prone Position
Most of the major spinal surgeries are performed in the supine position, which causes a decrease in stroke volume and cardiac index, which leads to the occurrence of hypotension during surgery.
- Trial name
- NCT05644483
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Low Back Pain, Lumbago
Home Program Education for Patients With Low Back Pain
The primary purpose of this study is to assess the effect size of the change in Oswestry Disability Questionnaire (ODQ) score over the 8 week follow-up period between the video based instruction or standard of care hand-out with…
- Conditions
- Low Back Pain, Lumbago, Spinal Instability
- Trial name
- NCT02427438
- Testing
- Video, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Lumbar Spine Degeneration
INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine
This investigation will provide safety and effectiveness information on the use of INFUSE® Bone Graft with the CAPSTONE® Spinal System and CD HORIZON® Spinal System with a Transforaminal Lumbar Interbody Fusion (TLIF) surgical…
- Trial name
- TLIF (NCT01415908)
- Testing
- INFUSE Bone Graft, Iliac Crest Bone Graft
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Medtronic Spinal and Biologics
Lumbar Spinal Stenosis, Lumbar Spine Instability
Ultrasound-guided ESP Block vs. Wound Infiltration in Lumbar Surgery: A Comparative Analysis (ESP:Erector Spinae Plane)
This study aimed to compare the efficacy of ultrasound-guided erector spinae plane block (ESPB) with that of wound infiltration (WI) for postoperative analgesia in lumbar spinal surgeries involving instrumentation.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spine Instability, Lumbar Spine Degeneration
- Trial name
- ESP (NCT06567964)
- Testing
- Erector Spinae Plane Block(ESPB), Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Intervertebral Disc Degeneration, Stenosis, Spinal
Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure
This study is designed to evaluate the clinical utility of a known intraoperative neuromonitoring modality (SSEP) using saphenous nerve as the site of stimulation to identify changes to the lumbar nerves which may be at risk…
- Conditions
- Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity
- Trial name
- NCT05648474
- Testing
- Somatosensory evoked potential [SSEP] intraoperative monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Alphatec Spine, Inc.
Traumatic Cervical Spine Instability
Anterior Only Surgery for Management of Traumatic Subaxial Cervical Spine Instability
Classic management of cervical spine sublaxation and dislocation is combined anterior and posterior approach. Unfortunately there are disadvantages for this approach like: increasing morbidity related to each approach, increasing…
- Trial name
- NCT03149497
- Testing
- anterior approach only in cervical spine trauma
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- arsany botros saleh
Lumbar Spine Instability, Lumbar Spinal Stenosis
Efficacy of Surgical Injection Lumbar Erector Spinae Plane Block
Lumbar spinal surgery is one of the operations performed for the treatment of leg and back pain. Severe pain may occur at postoperative period in patients following lumbar fusion surgery.
- Conditions
- Lumbar Spine Instability, Lumbar Spinal Stenosis, Lumbar Spine Degeneration
- Trial name
- NCT05630404
- Testing
- Surgical ESPB, US guided ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Spondylolisthesis
Efficacy of Hybrid Systems in Comparison to the Rigid Spondylodesis in Lumbar-spine Fusion
This study is designed as a randomized, parallel-group, therapy-controlled trial in a clinical care setting at a university hospital.
- Trial name
- D-Rod (NCT01852526)
- Testing
- Experimental: hybrid system, Active Comparator: Plif
- Where
- 2 sites in Germany
- Volunteers
- 5 people
- Sponsor
- University of Cologne
Musculoskeletal Pain, Postural Kyphosis
Posture and Musculoskeletal Pain in Dentists
Objectives: Musculoskeletal problems have been a concern in dentists for years. The aim of this study is to evaluate the relationship between posture and musculoskeletal pain in dentists.
- Conditions
- Musculoskeletal Pain, Postural Kyphosis, Spinal Instability
- Trial name
- Pain (NCT05673291)
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Spinal Metastases
Multicentric European Study In Patients With Vertebral Metastases
Train-METASTRA is a retrospective study that will be performed in order to collect a large and harmonised amount of clinical and imaging data concerning vertebral metastases, focusing in particular on the risk of fractures.
- Trial name
- NCT06220071
- Testing
- Case series review of clinical and radiographic data
- Where
- 3 sites in Germany, Hungary and 1 more
- Volunteers
- 356 people
- Sponsor
- Istituto Ortopedico Rizzoli
Spine Fracture, Degenerative Disc Disease
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Multicenter Post market clinical follow-up Study on the Safety and Performance of Ennovate® Cervical - Prospective, pure data collection of all Ennovate Cervical patients in Total Indications
- Conditions
- Spine Fracture, Degenerative Disc Disease, Spinal Instability, Spinal Tumor
- Trial name
- CERISE (NCT05296889)
- Testing
- posterior stabilization for the cervical spine
- Where
- 4 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Aesculap AG
Degenerative Disc Disease, Spinal Stenosis
Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws
Trinica Anterior Lumbar Plate (ALP) System is a commercially available, supplemental fusion device for use in the lumbar or sacral spine (L1-S1) to treat instability.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT00762723
- Testing
- Trinica Anterior Lumbar Plate System
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Zimmer Biomet