Clinical trials: Spine Osteoarthritis
PsA (Psoriatic Arthritis)
A Phase II Study to Evaluate the Efficacy and Safety of D-2570 in Subjects With Active Psoriatic Arthritis
This study is a multicenter, randomized, double-blind, placebo-controlled clinical trial. The target population is patients with active psoriatic arthritis. A total of 222 subjects are planned to be included.
- Trial name
- D2570-204 (NCT07315061)
- Testing
- D-2570
- Where
- China
- Volunteers
- 222 people
- Sponsor
- InventisBio Co., Ltd
Spondyloarthritis
Socio-economic Determinants for Acceptance and Choice of Biological Treatment
This was a cross-sectional study conducted at National center for rheumatic diseases, Nepal on SpA patient refractory to initial treatment with conventional anti rheumatic drugs.
- Trial name
- NCT04369651
- Volunteers
- 117 people
- Sponsor
- National Center for Rheumatic Diseases, Nepal
Ankylosing Spondylitis
Multi-omics Database for Integrative Microbiome Analysis in a Cohort of Korean Patients With Ankylosing Spondylitis
Multicenter Human Derivatives Prospective Cohort Study: Clinical information will be collected from patients with ankylosing spondylitis and their families who have provided research consent.
- Trial name
- NCT06076083
- Where
- 2 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Tae-Hwan Kim
Spondylarthropathies
Efficacy, Safety, and Tolerability Study of Infliximab in Juvenile Spondyloarthropathies
Tumor necrosis factor (TNF) alpha is a pro-inflammatory cytokine playing a significant role in the pathogenesis of the spondyloarthropathies (SpA).
- Trial name
- NCT00591201
- Testing
- infliximab
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Hospital General de Mexico
Axial Psoratic Arthritis
Study of the Efficacy and Safety of Secukinumab in Participants With Active Psoriatic Arthritis With Axial Skeleton Involvement
The purpose of this study is to demonstrate the efficacy and safety of secukinumab 150 mg or 300 mg in the management of axial manifestations in PsA patients who have failed to respond to at least 2 non-steroidal…
- Trial name
- MAXIMISE (NCT02721966)
- Testing
- Secukinumab
- Where
- 94 sites in Belgium, Bulgaria and 16 more
- Volunteers
- 503 people
- Sponsor
- Novartis Pharmaceuticals
Psoriatic Arthritis
An Effectiveness and Safety Study of CNTO 1275 in Patients With Active Psoriatic Arthritis
The purpose of this study is to evaluate the effectiveness and safety of CNTO 1275 (ustekinumab) in patients with psoriatic arthritis.
- Trial name
- NCT00267956
- Testing
- CNTO 1275 63 mg
- Where
- 25 sites in United States, Canada and 3 more
- Volunteers
- 146 people
- Sponsor
- Centocor, Inc.
Arthritis
Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis
The purpose of this research study is to see if patients with juvenile idiopathic arthritis or seronegative arthritis (and related conditions) mount protective immune responses to the human papillomavirus (HPV) vaccine called…
- Trial name
- CHASE (NCT00573651)
- Testing
- Blood Draws for Serum Titers
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- University Hospitals Cleveland Medical Center
Osteoarthritis
Comparing Mesenchymal Stem Cell Counts in Unilateral vs. Bilateral Posterior Superior Iliac Spine Bone Marrow Aspiration
Musculoskeletal conditions are common sources of pain. Specifically, osteoarthritis affects nearly 27 million people in the United States.
- Trial name
- NCT03014037
- Testing
- Unilateral Bone Marrow Procurement, Bilateral Bone Marrow Procurement
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Arthritis, Rheumatoid Arthritis
The Effects of Jing Si Herbal Tea Liquid Packets on Fatigue in Patients With Inflammatory Arthritis
Fatigue is a common feature in patients with rheumatic conditions. Fatigue can lead to a decline in physical function, self-confidence, cognitive status, and work performance and significantly impact the quality of life.
- Conditions
- Arthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT05257174
- Testing
- Jing Si Herbal Tea LIQUID PACKETS
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
An Observational, Prospective Study to Assess the Efficacy and Safety of Adalloce in Patients With RA and AS
This Study is to Assess the Efficacy and Safety of Adalloce in Patients With Rheumatoid Arthritis and Ankylosing Spondylitis, An Observational, Prospective Study
- Trial name
- NCT05835518
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yuhan Corporation
Spondyloarthritis (SpA)
Vunakizumab in Adults with Spondyloarthritis
This prospective, single-arm, multicenter study is aimed to explore the efficacy and safety of Vunakizumab in adults with spondyloarthritis.
- Trial name
- V SPA (NCT06770088)
- Testing
- vnacicizumab
- Volunteers
- 880 people
- Sponsor
- Sun Yat-sen University
Spondylitis, Ankylosing
Safety and Efficacy of Celecoxib Versus Diclofenac in the Treatment of Ankylosing Spondylitis
To compare the safety and efficacy of once-daily and twice-daily celecoxib versus diclofenac for the treatment of ankylosing spondylitis
- Trial name
- NCT00648141
- Testing
- Celecoxib, Diclofenac
- Where
- 47 sites in Germany
- Volunteers
- 458 people
- Sponsor
- Pfizer
Psoriasis
Post-Marketing Surveillance Study of OTEZLA
To evaluate the safety and efficacy of OTEZLA in actual clinical settings of use in patients with Psoriasis vulgaris that is with an inadequate response to topical therapies and Psoriasis arthropathica 1.
- Trial name
- NCT03284879
- Where
- Japan
- Volunteers
- 1,086 people
- Sponsor
- Amgen
Psoriatic Arthritis
Medication Adherence in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic multisystemic disease requiring ordinary doctor visits and an adherence to medication. Evaluating the parameters affecting the medication adherence is essential for the efficacy of the…
- Trial name
- NCT05223062
- Testing
- Disease activity in psoriatic arthritis (DAPSA), Compliance-Questionnaire-Rheumatology (CQR), The Brief Illness Perception Questionnaire (BIPQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Psoriatic Arthritis, Arthritis
99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity
Rheumatoid and psoriatic arthritis patients benefit from anti-TNF-α therapy, once it is effective in reducing joint and skin manifestations in 60-70% of patients with inflammatory articular joint and skin diseases.
- Trial name
- NCT02134613
- Testing
- 99mTc-anti-TNF-alpha Scintigraphy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Low Back Pain, Leg Pain
Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis
The purpose of this multi-center, randomized, clinical study is to establish the safety and effectiveness of the TOPS™ System, used following decompression, in the treatment of lower back and leg pain with, or without spinal…
- Conditions
- Low Back Pain, Leg Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00405691
- Testing
- "TOPS System" - Total Posterior Arthroplasty Implant
- Where
- 16 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Impliant, Ltd.
Psoriasis (PsO), Psoriasis Arthritis
Molecular Inflammation Board at the Center for Personalized Medicine
Molecular Inflammation Board at the Center for Personalized Medicine
- Conditions
- Psoriasis (PsO), Psoriasis Arthritis, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Spondylarthropathies
- Trial name
- MEB@ZPM (NCT07132333)
- Testing
- Biologic Agent
- Where
- Germany
- Volunteers
- 3,000 people
- Sponsor
- University Hospital Tuebingen
Musculoskeletal Diseases or Conditions, Spine; Arthrosis
The Safety of Pharmacopuncture on Musculoskeletal Patients
The purpose of this study is to evaluate the safety of pharmacopuncture by observing any adverse events that may occur after pharmacopuncture treatment in with spinal joint disease hospitalized patients at 7 Korean medicine…
- Trial name
- NCT05318859
- Testing
- Pharmacopuncture
- Where
- 7 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jaseng Medical Foundation
Psoriasis (PsO), Psoriatic Arthritis (PsA)
A Clinical Trial of Antiplatelets in Psoriasis
The purpose of this study is to determine the effect of antiplatelet therapy on the endovascular phenotype in psoriasis, specifically whether clopidogrel reduces vascular endothelial pro-atherosclerotic transcript expression more…
- Trial name
- NCT07744191
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis, Psoriatic Arthritis
The Effect of Brief Versus Individually Tailored Dietary Advice on Change in Lipids, Blood Pressure, and Diet in Patients With Inflammatory Joint Disease
A randomized controlled study comparing brief dietary intervention with a personal, tailored dietary advice (60 min) on change in LDL-c and change in diet.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Spondyloarthritis
- Trial name
- BETTER Diet (NCT05772325)
- Testing
- Individually tailored diet counseling, The brief standardized 4-minute heart healthy dietary advice
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
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