Clinical trials: Spine Osteoarthritis
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Prevention of Arthritis-Related Work Disability
People with rheumatic disorders (arthritis) often have trouble keeping their jobs. This study will look at whether vocational rehabilitation (VR) will improve the ability of employed people with arthritis to keep their jobs.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Knee, Ankylosing Spondylitis
- Trial name
- NCT00000416
- Testing
- Rehabilitation counseling
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Boston University Charles River Campus
Spondylitis, Ankylosing, Psoriatic Arthritis
Enhanced Clinics for Patients Diagnosed With Ankylosing Spondylitis and Psoriatic Arthritis
The 19.5 months project will pilot the introduction of a hospital-based, nurse-led ankylosing spondylitis (AS) and psoriatic arthritis (PsA) service for patients being initiated on biologic therapy in NHS Lothian Edinburgh…
- Trial name
- ECAP (NCT04341233)
- Sponsor
- NHS Lothian
Axial Spondyloarthritis, Ankylosing Spondylitis (AS)
The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study
An observational, ambispective cohort to learn about the disease progression of axial spondyloarthritis (axSpA) according to the changes from baseline in measures of disease activity, function, and imaging.
- Trial name
- DPCASPA (NCT06844643)
- Where
- China
- Volunteers
- 2,250 people
- Sponsor
- China-Japan Friendship Hospital
Patients With Axial SpA According to ASAS Criteria, Patients With Unilateral or Bilater Hip Damage According to BASRI Score
Hip Denervation and Intra-articular Hydration in Damaged Hip in Axial Spondyloarthritis Patients
Background: The hip joint is frequently affected in axial spondyloarthritis (SpA) of adults with destructive effects in untreated patients. About 35% of axial SpA patients had either unilateral or bilateral hip arthritis.
- Conditions
- Patients With Axial SpA According to ASAS Criteria, Patients With Unilateral or Bilater Hip Damage According to BASRI Score, Age > 18
- Trial name
- NCT05219084
- Testing
- hip denervation, intra-articular hydration, Combined group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Rheumatoid Arthritis, Ankylosing Spondylitis
bIosimilar of aDalimumab, an European evAluation
The study objective is aimed to describe all country, site, investigator and patient variables that lead to treatment persistence for at least 12 months among patients with rheumatologic and intestinal chronic inflammatory…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn Disease
- Trial name
- IDEA (NCT05190484)
- Volunteers
- 1,050 people
- Sponsor
- Fresenius Kabi
Peripheral Spondylarthritis
Exploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteria
In this Investigator Initiated study, the investigators want to explore the potential of an induction therapy with Tumor Necrosis Factor (TNF)-blocking agents in a very early disease stage (less than 3 months of symptom duration)…
- Trial name
- CRESPA (NCT01426815)
- Testing
- Golimumab
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Ankylosing Spondylitis
An Observational Study to Evaluate Safety and Efficacy of Remsima™ in Patients With Ankylosing Spondylitis
An Observational, Prospective Cohort Study to Evaluate Safety and Efficacy of RemsimaTM in Patients with Ankylosing Spondylitis
- Trial name
- NCT02557308
- Volunteers
- 329 people
- Sponsor
- Celltrion
Psoriatic Arthritis
A Study on Pharmacokinetics and Safety of BAT2506 Injection Versus Simponi®
This is a randomized, double-blind, parallel three-arm, and single-dose Phase I clinical study, designed to compare the similarity of pharmacokinetics, safety and immunogenicity between BAT2506 Injection and Simponi® (EU-licensed…
- Trial name
- NCT05332730
- Testing
- BAT2506 injection, Simponi® (EU commercially available product), Simponi® (US commercially available product)
- Where
- China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Psoriatic Arthritis, Work Productivity
To Observe the Impacts of Anti-Tumor Necrosis Factor (TNF) Effectiveness on Improvement in Work Place and Household Productivity for Patients With Psoriatic Arthritis (PsA)
This post marketing observational study is designed to provide the initial data on work impairment of PsA patients in Turkey, as well as changes in work impairment, life quality and clinical response during treatment with…
- Trial name
- NCT02028169
- Volunteers
- 120 people
- Sponsor
- AbbVie
Lumbar Spine Degeneration, Arthrosis; Spine
Postoperative Bracing Patterns After Lumbar Surgery
A variety of postoperative bracing are routinely applied after spinal procedures but there are limited data regarding their efficacy, especially with the increasing use of internal fixation.Currently, no data are available…
- Conditions
- Lumbar Spine Degeneration, Arthrosis; Spine, Surgery
- Trial name
- NCT03427281
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Axial Spondyloarthritis
A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis
The purpose of this study is to evaluate, in participants having achieved a state of sustained remission, if the ixekizumab treatment groups are superior to the placebo group in maintaining response during the randomized…
- Trial name
- NCT03129100
- Testing
- Ixekizumab
- Where
- 127 sites in United States, Argentina and 21 more
- Volunteers
- 773 people
- Sponsor
- Eli Lilly and Company
Psoriatic Arthritis, Psoriasis
Assessment of Fatigue in Psoriatic Arthritis and Cutaneous Psoriasis Patients
Psoriatic arthritis is characterized with pain, swelling and joint stiffness. These are inflammatory reactions against tendons, ligaments and joints associated with fatigue.
- Trial name
- RPso-Fatigue (NCT06101706)
- Testing
- Fatigue assessment, Quality of life assessment, Assess severity of psoriatic arthritis
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Axial Spondyloarthritis
Effects of Nonsteroidal Anti-Inflammatory Drugs in Recurrence of Spondyloarthritis Patients After Remission
The multicenter, randomized controlled trial is to investigate and evaluate the effect of NSAIDs therapy on recurrence in patients with axial spondyloarthritis;
- Trial name
- NCT03425812
- Testing
- To withdraw NSAIDs therapy, To continue NSAIDs therapy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Ankylosing Spondylitis
Effect of Inspiratory Muscle Training on Respiratory Functions and Exercise Capacity
In this study, we aimed to evaluate the effect of Anti- tumor necrosis factor (TNF) treatment on pulmonary functions in patients with AS and to evaluate the pulmonary functions and exercise performance of patients by adding…
- Trial name
- NCT06287983
- Testing
- Inspiratory Muscle Trainer (IMT) (POWERbreathe Medic Classic), The Sample Spondylitis Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kayseri City Hospital
Ankylosing Spondylitis
Evaluation of Physical Performance in Ankylosing Spondylitis Patients
Ankylosing spondylitis (AS) can cause serious limitations in individuals' physical performance, as it involves the musculoskeletal system and can cause ankylosis and arthritis in both axial and peripheral joints.
- Trial name
- NCT04451681
- Testing
- Cardiopulmonary exercise test
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Osteoarthritis
Patient Observational Pain and Activity Survey (POPAS) Study Using RS-4i Sequential Stimulator With Intersperse Technology in Axial Spine and Peripheral Joint Pain
Spine pain and joint pain are among the most common worldwide ailments and directly contributes to disability as well as increased duration of care.
- Trial name
- NCT05478265
- Testing
- RS-4i Plus
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Spondylodiscitis, Spinal Infection
Evaluation of Outcomes of Surgical Treatment for Nonspecific Infectious Spondylodiscitis Via Posterior Approach in One Center.
Non-specific spondylodiscitis is a bacterial infection of the spine that in some cases requires surgical treatment. The basis of surgical treatment is the removal of affected tissues.
- Conditions
- Spondylodiscitis, Spinal Infection, Spondylitis, Discitis
- Trial name
- NCT07349602
- Testing
- Posterior approach to infection site
- Where
- Russia
- Volunteers
- 47 people
- Sponsor
- Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty
Psoriatic Arthritis
Stronger Together Psoriatic Arthritis Wellness Study
Patients diagnosed with psoriatic arthritis (PsA) confront decisions about how to treat their disease, interact with their health care providers, and modify lifestyle choices that may improve treatment outcomes.
- Trial name
- NCT05652608
- Testing
- Immune Strength
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Global Healthy Living Foundation
Arthritis, Psoriatic
A Study to Test Different Doses of BI 730357 and Find Out Whether They Reduce Symptoms in People With Active Psoriatic Arthritis
This study is open to adults with active psoriatic arthritis who have tender and swollen joints. The purpose of this study is to find out whether a medicine called BI 730357 helps to reduce symptoms and to prevent damage to…
- Trial name
- NCT04680676
- Testing
- BI 730357
- Sponsor
- Boehringer Ingelheim
Ankylosing Spondylitis
Phase II Clinical Study of Thalidomide in the Treatment of Ankylosing Spondylitis
1. Evaluate the efficacy and safety of taking thalidomide tablets once daily in the treatment of active ankylosing spondylitis. 2.
- Trial name
- NCT02201043
- Testing
- Thalidomide 150mg, Thalidomide 100mg
- Where
- 9 sites in China
- Volunteers
- 197 people
- Sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
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