Clinical trials: Spirometry, open to volunteers
Rib Fractures, Spirometry
Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures
In patients admitted following a trauma, the incidence of multiple rib fractures is reported to be 9,7%, and this can be even higher in high energy trauma like motor vehicle accidents (1).
- Trial name
- NCT05105399
- Testing
- Serratus plane block (continuous or single-shot)
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Niguarda Hospital
Spirometry
The INTERvening for LUNG Health Trial
This research study is being done to find out whether a community health volunteer-delivered, multi-component program can improve lung health for people at risk of chronic respiratory diseases (such as asthma or COPD) in…
- Trial name
- INTERLUNG (NCT07540000)
- Testing
- Community health worker-delivered multi-component respiratory health intervention
- Where
- 2 sites in United States, Nepal
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Asthma
Impact of Educational Intervention Protocol on the Level of Knowledge, Clinical Control and Lung Function of People With Asthma
The goal of this randomized controlled clinical trial is to evaluate the effects of a proposed educational intervention on people with asthma.
- Trial name
- NCT06878352
- Testing
- Educational intervention BUNDLE, prepared in accordance with the recommendations of the Global Initiative for Asthma- GINA (2024)).
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Paraíba
Obesity & Overweight, Inflammation
Assessment of Respiratory Dysfunction in Obesity and the Use of IMT.
The aim of the project will be to assess the functional condition of the respiratory tract and inflammation resulting from obesity, as well as the possibility of using inspiratory muscle training as a factor reducing the…
- Conditions
- Obesity & Overweight, Inflammation, Ventilation Disorders
- Trial name
- IMT (NCT07307417)
- Testing
- inspiratory muscle training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Bronchial Asthma, Vitamin D Deficiency
Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma
Asthma is a chronic inflammatory airway disease associated with variable airflow limitation and persistent respiratory symptoms.
- Conditions
- Bronchial Asthma, Vitamin D Deficiency, Pulmonary Function Impairment, Oxidative Stress
- Trial name
- VD-ASTHMA (NCT07733635)
- Volunteers
- 134 people
- Sponsor
- Sinai University
Pulmonary Function, Aerobic Performance
Pulmonary Function and Trunk Muscle Performance in Wrestlers
This study aims to investigate the relationships among pulmonary function, aerobic performance, anaerobic performance, and isokinetic trunk muscle performance in professional male wrestlers.
- Conditions
- Pulmonary Function, Aerobic Performance, Anaerobic Performance, Isokinetic Test
- Trial name
- NCT07792174
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Asthma Bronchiale, COPD
Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief
A bronchodilator reversibility test is widely used in the diagnosis and management of obstructive lung diseases. Bronchodilators relieve symptoms in asthma and COPD.
- Conditions
- Asthma Bronchiale, COPD, Bronchodilation, Spirometry
- Trial name
- NCT07364188
- Testing
- Bronchodilator
- Volunteers
- 120 people
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Asthma (Diagnosis), Pulmonary Function
Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia)
This study explores a potential new treatment for adults with moderate-to-severe asthma using a drug called linvemastat, which targets an enzyme linked to lung inflammation.
- Conditions
- Asthma (Diagnosis), Pulmonary Function, Moderate-to-Severe Asthma
- Trial name
- syMMPonia (NCT07191535)
- Testing
- linvemastat
- Volunteers
- 135 people
- Sponsor
- Foresee Pharmaceuticals Co., Ltd.
Dysarthria, Acquired Brain Injury
ACURES: Acoustic and Respiratory Parameters for Dysarthria Assessment
The goal of this observational study is to describe speech and breathing patterns in adults after acquired brain injury (ABI) and understand how these patterns relate to the presence, severity, and type of dysarthria.
- Trial name
- ACURES (NCT07435155)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Salamanca
Bronchial Obstruction, Premature Birth
PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled Tiotropium
The purpose of this clinical trial is to evaluate the efficacy and safety of inhaled tiotropium bromide (Spiriva Respimat) in preterm-born children and adolescents suffering from chronic bronchial obstruction.
- Trial name
- PRETIO (NCT07827859)
- Testing
- tiotropium bromide (Spiriva Respimat)
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- General University Hospital, Prague
Preserved Ratio Impaired Spirometry
Bufei Recipe Reduces the Incidence Rate of COPD
Establish early TCM prevention and treatment program to reduce the incidence rate of COPD.
- Trial name
- NCT06375824
- Testing
- Bufei Recipe
- Volunteers
- 1,100 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Mitigating Chronic Respiratory Disease Through the Lens of Multi-Morbidity
The investigators aim to make it easier to find people with undiagnosed long-term lung health problems (such as asthma, and chronic obstructive pulmonary disease, COPD, collectively called 'Chronic Respiratory Diseases', CRDs)…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Preserved Ratio Impaired Spirometry
- Trial name
- MARES1 (NCT07050823)
- Where
- 2 sites in Brazil
- Volunteers
- 859 people
- Sponsor
- University College, London
Preserved Ratio Impaired Spirometry (PRISM)
Role of Exercise in PRISm and Subsequent Development of COPD
Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted.
- Trial name
- NCT07387432
- Testing
- Exercise with telehealth group, Exercise group, No exercise group
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Dyspnea
- Trial name
- BETTER COPD-PH (NCT05937854)
- Testing
- Tadalafil
- Where
- 5 sites in United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Chronic Obstructive Pulmonary Disease (COPD)
Intermittent Hypoxemia, Lung Function Decline, Morbidity, and Mortality in COPD (PROSA Study).
This study aims to analyze if patients with chronic obstructive lung disease who experience a decline of blood oxygen saturation during physical exercise have a disease course different from that of COPD patients who do not…
- Trial name
- PROSA (NCT06265623)
- Testing
- No active intervention, but observational follow-up
- Where
- Germany
- Volunteers
- 148 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Asthma
Alternate Nostril Breathing With Incentive Spirometry on Lung Function Among Asthma Patients
To compare effects of Alternate Nostril Breathing exercise with incentive spirometer on lung functions (forced vital capacity, forced expiratory volume, and peak expiratory flow rate) in Asthma patients.
- Trial name
- NCT07110116
- Testing
- Alternate nostril breathing with Incentive Spirometery, Incentive spirometery
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Common Variable Immunodeficiency
Usage of Spirometry in Managing IgG Therapy in CVID With Airway Disease
Although there is evidence in the literature that gammaglobulin replacement therapy can lead to a reduction in the prevalence of pulmonary infection and improved lung function, there is no published study to guide immunologists…
- Trial name
- NCT05193552
- Testing
- Hizentra
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cystic Fibrosis (CF)
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.
- Trial name
- ADMP-CF (NCT07729787)
- Testing
- Autogenic Drainage, Mechanical Percussion
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Post Operative
Comparing Use of Incentive Spirometry With and Without Reminder
This study is designed to determine if patients using an incentive spirometer with visual and auditory signals will increase their use of the incentive spirometer and prevent lung complications.
- Trial name
- NCT06101030
- Testing
- Signal On
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Tidal Medical Technologies
Thoracic Surgery
ACBT With Incentive Spirometry Versus High-Frequency Chest Wall Oscillation After Thoracic Surgery
This randomized clinical trial aims to compare the effectiveness of Active Cycle of Breathing Techniques combined with Incentive Spirometry (ACBT + IS) versus High-Frequency Chest Wall Oscillation (HFCWO) in patients undergoing…
- Trial name
- NCT07619716
- Testing
- Active Cycle of Breathing Techniques with Incentive Spirometry, High-Frequency Chest Wall Oscillation
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University