Clinical trials: Spondylarthropathy
Arthritis, Psoriatic
Psoriatic Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to NSAIDs or Non-biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) Therapy
The purpose of this study is to characterize the safety, efficacy and dose response of BMS-945429 in subjects with active Psoriatic Arthritis and an inadequate response to Nonsteroidal anti-inflammatory drugs (NSAIDs) and…
- Trial name
- NCT01490450
- Testing
- BMS-945429
- Where
- 49 sites in United States, Argentina and 11 more
- Volunteers
- 165 people
- Sponsor
- CSL Behring
Ankylosing Spondyloarthritis
Study of Apremilast to Treat Subjects With Active Ankylosing Spondylitis
Apremilast is a new, orally available, small molecule drug that specifically inhibits phosphodiesterase 4 (PDE4), an enzyme that modulates inflammatory cytokines.
- Trial name
- POSTURE (NCT01583374)
- Testing
- Apremilast tablet 20 mg, Apremilast tablet 30 mg BID
- Where
- 103 sites in United States, Australia and 16 more
- Volunteers
- 490 people
- Sponsor
- Amgen
Psoriatic Arthritis (PsA)
Safety and Effectiveness of Abatacept in Psoriatic Arthritis Participants
The purpose of this study is a long-term, observational study of Abatacept in patients with Psoriatic Arthritis, a chronic inflammatory disorder.
- Trial name
- ALTEA (NCT03419143)
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Bristol-Myers Squibb
Ankylosing Spondylitis
Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy
The primary objective of this study is to evaluate the effect of filgotinib versus placebo on signs and symptoms of active ankylosing spondylitis (AS), evaluated by Assessment of SpondyloArthritis international Society 40%…
- Trial name
- SEALION2-NAÏVE (NCT04483700)
- Testing
- Filgotinib
- Sponsor
- Gilead Sciences
Spondylitis, Ankylosing
A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)
The purpose of the study is to evaluate the efficacy and tolerability of two doses of etoricoxib compared to naproxen in the treatment of ankylosing spondylitis (AS).
- Trial name
- NCT01208207
- Testing
- Part I - etoricoxib 60 mg, Part I - etoricoxib 90 mg, Part I- naproxen 1000 mg
- Volunteers
- 1,015 people
- Sponsor
- Organon and Co
Psoriatic Arthritis
A Study to Characterize Profile of Participant With Psoriatic Arthritis Depending on Whether Their Disease is Managed by a Dermatologist or by a Rheumatologist, and Starting Ustekinumab
The primary purpose of this study is to describe the Psoriatic Arthritis (PsA) participant profiles depending on whether their disease is managed by a dermatologist or by a rheumatologist in routine practice.
- Trial name
- PROUST (NCT03336281)
- Testing
- Ustekinumab
- Where
- France
- Volunteers
- 221 people
- Sponsor
- Janssen Cilag S.A.S.
Rheumatoid Arthritis, Spondyloarthritis, Axial
Cohort Project of Patients With Inflammatory Rheumatism
Chronic inflammatory rheumatism (CIR) is a group of inflammatory diseases that affect the joints and spine and are related to an abnormal immune response.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Axial, Psoriatic Arthritis
- Trial name
- SMAP (NCT06059430)
- Testing
- no intervention
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ankylosing Spondylitis
Clinical Trial of Osteoporosis in Ankylosing Spondylitis
This is an observational study aiming to study the prevalence and risk factors for osteoporosis and vertebral fractures in patients with ankylosing spondylitis attending three Rheumatology clinics in Western Sweden.
- Trial name
- NCT00858819
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Göteborg University
Ankylosing Spondylitis, Axial Spondyloarthritis
Terbinafine Treatment of Axial Spondyloarthropathy
This is a pilot study to determine if further research is warranted to assess if anti-fungal therapy is an effective adjunctive treatment for axial spondyloarthropathy
- Conditions
- Ankylosing Spondylitis, Axial Spondyloarthritis, Psoriatic Spondylitis, Spondylitis Secondary to Inflammatory Bowel Disease
- Trial name
- FUN (NCT05119712)
- Testing
- Terbinafine Tablets, Laboratory Testing
- Where
- United States
- Sponsor
- Oregon Health and Science University
Ankylosing Spondylitis
Resistance Training Exercise Using the Swiss Ball in Ankylosing Spondylitis
The aim of the present study is to assess the effectiveness of resistance training with swiss ball in the treatment of patients with ankylosing spondylitis.
- Trial name
- NCT01351311
- Testing
- Exercise, Drug treatment
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)
A Post-marketing Study on the Safety of Abatacept Treatment in Denmark Using the Danish Database
The purpose of this study is to expand on the ongoing post-marketing monitoring of abatacept to include all participants with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) treated with abatacept captured in Danish…
- Trial name
- DANBIO (NCT05421442)
- Where
- United States
- Volunteers
- 38,396 people
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis, Psoriatic Arthritis
Vaccine Response to COVID-19 Vaccines in Patients Using Immunosuppressive Medication
The purpose of this study is to assess the strength and duration of the immunological response to COVID-19 vaccines in patients treated with immunosuppressive and/or immunomodulating medication for immune-mediated inflammatory…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Spondyloarthritis, Crohn Disease
- Trial name
- Nor-vaC (NCT04798625)
- Where
- 2 sites in Norway
- Volunteers
- 2,300 people
- Sponsor
- Diakonhjemmet Hospital
Rheumatoid Arthritis, Psoriatic Arthritis
Tapering of Biologics in Inflammatory Arthritis Patients in Remission
Rheumatoid arthritis (RA) and Psoriatic Arthritis (PsA) are types of inflammatory arthritis. They are disabling conditions caused by inflammation in joints that can lead to pain, stiffness, fatigue and joint damage.
- Trial name
- TAPER (NCT04429776)
- Testing
- Drug level testing with feedback provided, Drug level testing with no feedback provided
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University of Manchester
Ankylosing Spondylitis
Relationship Between Diet, Oxidative Stress and Inflammation in Ankylosing Spondylitis
Ankylosing Spondylitis (AS) is a chronic inflammatory autoimmune disease. The aim of this study is to reveal the relationship between dietary intake, blood total antioxidant capacity and disease activity in individuals with AS.
- Trial name
- NCT04772976
- Testing
- Observational study, not applicable
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Psoriatic Arthritis, Inflammatory Bowel Diseases
Frequency of Elevated Fecal Calprotectin Levels in Psoriatic Arthritis.
Background.Recent epidemiologic studies have shown an association between psoriasis, psoriatic arthritis (PsA) and inflammatory bowel diseases (IBD).
- Trial name
- NCT04190108
- Testing
- Fecal calprotectin assay
- Where
- Italy
- Volunteers
- 259 people
- Sponsor
- Hospital of Prato
Axial Spondyloarthritis and Ankylosing Spondylitis
The Effect of Aerobic Exercises and Yoga Exercises in Axial Spondyloarthritis
Axial Spondyloarthritis (AxSpA), mainly affecting the axial skeleton and sacroiliac joints, is a chronic, systemic, inflammatory disease that causes structural and functional disorders.
- Trial name
- NCT06138717
- Testing
- yoga based exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Posterior Tibial Tendon Dysfunction, Pes Planus
Frequency of Pes Planus and Posterior Tibial Tendon Dysfunction in Patients With Ankylosing Spondylitis
This investigation aims to investigate the frequency of pes planus and posterior tibial tendon dysfunction in patients with ankylosing spondylitis.
- Conditions
- Posterior Tibial Tendon Dysfunction, Pes Planus, Spondylitis, Ankylosing
- Trial name
- NCT04810715
- Testing
- Patients with Ankylosing Spondylitis
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Afyonkarahisar Health Sciences University
Rheumatoid Arthritis, Ankylosing Spondylitis
T Cells and TNF (Tumor Necrosis Factor): The Impact of TNF Blockade
We aim to translate these findings into patients with rheumatoid arthritis and other conditions treated with anti-TNF (anti-tumor necrosis factor) therapy, such as psoriatic arthritis and ankylosing spondylitis.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT01060098
- Testing
- anti-TNF therapy (etanercept or adalimumab)
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Imperial College London
Psoriasis, Psoriatic Arthritis
Prevalence of Psoriatic Arthritis in Adults With Psoriasis: An Estimate From Dermatology Practice
This is a phase 4, multicenter, randomized, non-therapeutic interventional trial in subjects with psoriasis looking for the prevalence of psoriatic arthritis.
- Trial name
- PREPARE (NCT01147874)
- Testing
- lab draws and imaging
- Where
- 45 sites in United States, Belgium and 5 more
- Volunteers
- 1,013 people
- Sponsor
- Pfizer
Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)
COMFI - a COMbined Fatigue Intervention
Background: Inflammatory arthritis (IA) encompasses autoimmune rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis.
- Conditions
- Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Spondyloarthritis (SpA), Inflammatory Arthritis
- Trial name
- COMFI (NCT06666452)
- Testing
- COMFI - a COMbined Fatigue Intervention
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 39 people
- Sponsor
- The Danish Center for Expertise in Rheumatology
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