Clinical trials: Spondyloarthritis, Axial
Ankylosing Spondylitis
Clinical Trial to Evaluate Efficacy and Safety of Multiple Subcutaneous Injections of Various Doses of BCD-085 in Patients With Active Ankylosing Spondylitis
BCD-085-3 is a next step in clinical investigation of BCD-085. BCD-085 is a monoclonal antibody to interleukin 17. During the trial patients with active ankylosing spondylitis will receive 40, 80 or 120 mg of BCD-085…
- Trial name
- NCT02763111
- Testing
- BCD-085
- Volunteers
- 88 people
- Sponsor
- Biocad
Ankylosing Spondylitis
Study Evaluating Etanercept in the Treatment of Subjects With Ankylosing Spondylitis
This study will represent the sponsor's first controlled study of etanercept in Chinese subjects with Ankylosing Spondytitis (AS).
- Trial name
- NCT00434044
- Testing
- Enbrel (etanercept)
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Axial Spondyloarthritis
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
This study is comparing 200 milligrams (mg) of filgotinib a day with a placebo to see if filgotinib helps to treat Axial Spondyloarthritis (axSpA) and is safe to use.
- Trial name
- OLINGUITO (NCT05785611)
- Testing
- Filgotinib
- Where
- 123 sites in Belgium, Bulgaria and 16 more
- Volunteers
- 495 people
- Sponsor
- Alfasigma S.p.A.
Spondylitis, Ankylosing
A Study of RoActemra/Actemra (Tocilizumab) in Patients With Ankylosing Spondylitis Who Have Failed Treatment With NSAIDs
This randomized, double-blind, placebo-controlled study will evaluate the safety and efficacy of RoActemra/Actemra (tocilizumab) in patients with ankylosing spondylitis (AS) who have failed treatment with non-steroidal…
- Trial name
- NCT01209702
- Testing
- tocilizumab
- Where
- 139 sites in United States, Australia and 16 more
- Volunteers
- 306 people
- Sponsor
- Hoffmann-La Roche
Ankylosing Spondylitis (AS), Mental Health
An Ecological Momentary Intervention for Mental Health in Individuals With Ankylosing Spondylitis
Ankylosing spondylitis is a chronic inflammatory rheumatic disease associated with pain, stiffness, reduced mobility, and impaired quality of life.
- Trial name
- NCT07647965
- Testing
- Ecological Momentary Intervention, Attention Control Group
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Axial Spondyloarthritis
Safety, Tolerability and PK of SHR1314 in axSpA
The main purpose of this study is to evaluate the safety, Tolerability and Pharmacokinetics (PK) of SHR1314 with axial spondyloarthritis.
- Trial name
- NCT03704428
- Testing
- SHR-1314
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Ankylosing Spondylitis (AS)
Cardiovascular Disease Risk Factors and Healthy Lifestyle Behaviours in Patients with Ankylosing Spondylitis
A review of the literature did not identify any studies that assessed knowledge of cardiovascular disease risk factors and healthy lifestyle behaviours in patients with ankylosing spondylitis.
- Trial name
- NCT06650228
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Ankylosing Spondylitis and Psoriatic Arthritis Patients
TNFAIP3 Gene Expression in Ankylosing Spondylitis and Psoriatic Arthritis Patients and Its Relation to Disease Activity
1. Identify gene expression of TNFAIP3 in ankylosing spondylitis and psoriatic arthritis patients. 2. Detect relation between TNFAIP3 and disease activity. Inclusion criteria: 1.
- Trial name
- NCT07507487
- Testing
- Detection of TNFAIP3 gene expression by real time PCR.
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Asmaa Hassan mohamed Abdel Mawjoud
Axial Spondyloarthritis and Ankylosing Spondylitis
Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by pain, morning stiffness, restricted spinal mobility, and systemic manifestations.
- Trial name
- NCT07833033
- Testing
- Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Health-Related Quality of Life and Disease-Related Costs: Comparison Between Ankylosing Spondylitis, Rheumatoid Arthritis and Systemic Lupus Erythematosus in Taiwan
Ankylosing spondylitis (AS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are the most common rheumatic diseases dealt with rheumatologists in Taiwan.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Ankylosing Spondylitis
- Trial name
- NCT00747578
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taichung Veterans General Hospital
Psoriatic Arthritis
Axial Involvement in Psoriatic Arthritis Cohort
This is a multinational multicenter cross-sectional study in patients with a definite diagnosis of PsA. The population of interest will consist of 400 adult patients diagnosed with PsA and fulfilling the classification criteria…
- Trial name
- AXIS (NCT04434885)
- Testing
- Clinical and imaging examination of symptoms and signs suggestive of axial involvement
- Where
- 2 sites in Canada, Germany
- Volunteers
- 400 people
- Sponsor
- Charite University, Berlin, Germany
Axial Spondyloarthritis
Clinical Trial of TCM Collaborative Care Model in Axial Spondyloarthritis
A pragmatic, prospective, randomized controlled trial will be conducted in patients with axial spondyloarthritis who are NSAID inadequate responders.
- Trial name
- AcuSpA (NCT03420404)
- Testing
- TCM physician involved collaborative care model (TCMCMC)
- Where
- Singapore
- Volunteers
- 140 people
- Sponsor
- Singapore General Hospital
Spondyloarthritis, Axial Spondyloarthritis
Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT
To evaluate the potential usefulness of 68Ga-FAPI PET/CT for the diagnosis, inflammation evaluation and prognosis prediction in spondyloarthritis.
- Conditions
- Spondyloarthritis, Axial Spondyloarthritis, Ankylosing Spondylitis
- Trial name
- NCT05999643
- Testing
- Drug: 68Ga-FAPI
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Systemic Lupus Erythematosus, Sjogren's Syndrome
COVID-19 Vaccination in Rheumatic Disease Patients
The research is being done to study the immune responses to COVID-19 vaccination in patients with rheumatic diseases.
- Conditions
- Systemic Lupus Erythematosus, Sjogren's Syndrome, Inflammatory Myositis, Psoriatic Arthritis
- Trial name
- NCT04839315
- Testing
- mRNA COVD19 vaccine
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Ankylosing Spondylitis
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis
The purpose of the study is to demonstrate the efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared to placebo in the treatment of subjects with active ankylosing spondylitis (AS).
- Trial name
- BE MOBILE 2 (NCT03928743)
- Testing
- Bimekizumab
- Where
- 83 sites in United States, Belgium and 12 more
- Volunteers
- 332 people
- Sponsor
- UCB Biopharma SRL
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice
The purpose of this non-interventional, multicenter, post-marketing observational study (PMOS) was to assess rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), plaque psoriasis (PS), Crohn's…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn´s Disease
- Trial name
- Adherence (NCT01768858)
- Testing
- Adalimumab
- Volunteers
- 96 people
- Sponsor
- AbbVie
Ankylosing Spondylitis
Stretching in Water and on Land for Patients With Ankylosing Spondylitis
The aim of the study is to investigate the effectiveness stretching exercises in ankylosing spondylitis.
- Trial name
- NCT03667625
- Testing
- Multidimensional Mobility Exercises, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Dokuz Eylul University
Ankylosing Spondylitis, Low Back Pain
The Effect of Acupuncture in Treating Chronic Low-back Pain
The purpose of this study is to evaluate the efficiency of acupuncture in treating chronic low-back pain
- Trial name
- NCT02260284
- Testing
- Yaotong points acupuncture, the usual care, standardized acupuncture
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chengdu PLA General Hospital
Ankylosing Spondylitis
The Impacts of Gluten-free Diet in Patients With Ankylosing Spondylitis
Subclinical intestinal inflammation and intestinal permeability have been reported in patients with ankylosing spondylitis. Gluten is one of the main triggers of zonulin releaseand gluten intake may contribute to the development…
- Trial name
- NCT07166874
- Testing
- Gluten Free Diet
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Ankylosing Spondylitis
Program evaLuating the Autoimmune Disease iNvEstigational Drug cT-p13 in AS Patients(PLANETAS)
This study is the trial to demonstrate how our product is similar to remicade by comparing the results of blood samples in active Ankylosing Spondylitis patients.
- Trial name
- NCT01220518
- Testing
- Infliximab
- Where
- South Korea
- Volunteers
- 257 people
- Sponsor
- Celltrion