Clinical trials: Spondylolisthesis
Lumbar Spondylolisthesis, Degenerative Disc Disease
Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease
The objective of this study is to perform a prospective, randomized, controlled clinical trial to compare radiographic fusion rates and patient reported outcomes, including pain and function preoperatively and postoperatively…
- Conditions
- Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy
- Trial name
- ViviGen (NCT03733626)
- Testing
- ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Lumbar Spine Degeneration, Lumbar Spine Instability
Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial
Symptomatic lumbar spinal stenosis is the most common indication for spinal surgery. However, more than one-third of the patients undergoing surgery for lumbar stenosis report dissatisfaction with the results.
- Conditions
- Lumbar Spine Degeneration, Lumbar Spine Instability, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT05527145
- Testing
- Minimally invasive surgery, Percutaneous Spacer
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Roma La Sapienza
Degenerative Spondylolisthesis, Lumbar Spondylosis
Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion
The purpose of this early study is to compare the clinical results of the new Conduit Interbody device to the traditional Concorde Bullet Device.
- Conditions
- Degenerative Spondylolisthesis, Lumbar Spondylosis, Lumbar Spondylolisthesis
- Trial name
- NCT05993195
- Testing
- Conduit Titanium Interbody Graft, Concorde Bullet Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Lahey Clinic
Degenerative Spondylolisthesis G1
Platelet Rich Plasma Injection Versus Surgical Fixation Procedure in Management of Spondylolisthesis grade1.
Spondylolisthesis is a serious health condition that is often treated with surgery or pain-relieving lumbar epidural steroids. Patients with persistent and debilitating symptoms who have failed to respond to conservative…
- Trial name
- NCT04808336
- Testing
- PRP injection., fixation surgical procedure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Spinal Fusion, Spondylolisthesis
Spine Registration Using 3D Scanning - Arise
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
- Conditions
- Spinal Fusion, Spondylolisthesis, Scoliosis, Sciatica
- Trial name
- NCT05195593
- Testing
- Optical 3D Scanner
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Advanced Scanners Inc.
Low Back Pain, Spondylolisthesis
Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device
Lumbar spinal fusion is commonly performed as a "last resort" in patients with chronic low back pain caused by degenerative changes and instability of the spine.
- Conditions
- Low Back Pain, Spondylolisthesis, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT00095095
- Testing
- Lumbar Interbody Fusion
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 102 people
- Sponsor
- Medtronic Spinal and Biologics
Lumbar Spinal Stenosis, Spondylolisthesis
Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS), is a common disorder of narrowing of the spinal canal in the lower part of the back. This causes discomfort in the legs when standing or walking because of pressure on the spinal nerves.There are…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT01455805
- Testing
- Minuteman Fusion Implant, surgical decompression
- Where
- 4 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Spinal Simplicity LLC
Degeneration of Lumbar Intervertebral Disc, Degenerative Spondylolisthesis
Lumbar Fusion With The Icotec CF/PEEK Pedicle System In Combination With The Icotec CF/PEEK TLIF Cage ETurn™
The objective of the PMCF is to collect outcome information on patients suffering from symptomatic degenerative disc disease or degenerative spondylolisthesis requiring 1- or 2-level lumbar or lumbar-sacral spinal fusion with…
- Trial name
- NCT02087267
- Testing
- 1- or 2-level spinal fusion
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 94 people
- Sponsor
- Sitona AG
Sciatica
Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients With Sciatica
Disc herniation, stenosis of the spine and spondylolisthesis are the common causes of radiculitis in medical practice today, and can cause symptoms of sciatica.
- Trial name
- NCT03801512
- Testing
- Steroid, Acupuncture, Platelet Rich Plasma
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University Hospital
Spondylolisthesis, Erosive Osteochondrosis in L2-S1
Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine
Does a new "topping-off" device lead to a better clinical outcome compared to standard fusion? Does this device prevent the development of adjacent instability? Does radiological adjacent instability correlate with clinical…
- Trial name
- Topping-off (NCT01224379)
- Testing
- Topping off system, monosegmental PLIF
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Cologne
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Low Back Pain, Sciatica
- Trial name
- NCT03879447
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Jaseng Medical Foundation
Degenerative Disc Disease, Degenerative Spondylolisthesis
Modulus in XLIF Study
The primary objective of this study is to evaluate the safety and performance of the Modulus 3D-printed titanium interbody implant in patients undergoing thoracic and/or lumbar XLIF as measured by reported complications…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis
- Trial name
- NCT04418817
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- NuVasive
Degenerative Disc Disease, Spondylolisthesis
Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.
The objectives of this longitudinal study are to assess and measure fusion status (fused or not fused) and rate of bony fusion using NanoBone® Synthetic Bone Graft in patients requiring one to two level lumbar posterolateral…
- Trial name
- BONE (NCT04615260)
- Testing
- NanoBone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Artoss Inc.
Low Back Pain, Spondylolisthesis
Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain
Lumbar spinal fusion was introduced approximately 70 years ago and has evolved as a treatment option for symptomatic spinal instability, spinal stenosis, spondylolisthesis, and degenerative scoliosis.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis, Spinal Instability
- Trial name
- NCT01918943
- Testing
- PLIF and Aspen (spinous process fixation device)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- American British Cowdray Medical Center
Lumbar Spondylolisthesis, Unilateral Biportal Endoscopy
A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis
Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP).
- Conditions
- Lumbar Spondylolisthesis, Unilateral Biportal Endoscopy, Minimally Invasive Technique, Surgical Treatment
- Trial name
- NCT05480267
- Testing
- surgical treatment for lumbar spondylolisthesis
- Volunteers
- 340 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Degenerative Disc Disease, Spondylolisthesis
Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion
This study is undertaken to evaluate the outcomes of Oblique Lateral Lumbar Interbody Fusion (OLLIF). Specifically, the study seeks to measure outcomes on radiological imaging, outcomes reported by the patients on standardized…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT03726190
- Testing
- Oblique Lateral Lumbar Fusion
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Tristate Brain and Spine Institute
Lumbar Disc Herniation, Spondylolisthesis
The Spine PROMCO Study
Our primary objective is to design a cohort to determine the treatment outcome of different surgical interventions of the degenerative lumbar spine highlighting the expediency and value of the current surgical treatment program.
- Conditions
- Lumbar Disc Herniation, Spondylolisthesis, Spinal Stenosis
- Trial name
- Spine PROMCO (NCT05963815)
- Testing
- Spine surgery
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- Park Medical centrum
Degenerative Spondylolisthesis
SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis
This trial, conducted in adult patients with degenerative spondylolisthesis needing surgical treatment at one level, aimed at comparing two approaches of spinal fusion.
- Trial name
- SPONGIT (NCT00869882)
- Testing
- Circumferential arthrodesis, Posterolateral fusion with instrumentation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Spondylolisthesis
Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis
A prospective multi-centre, randomised, controlled study to evaluate the safety and preliminary effectiveness of NVD-001 for the treatment of low grade degenerative lumbar spondylolisthesis by interbody fusion (L1 - S1).
- Trial name
- Spine1 (NCT03100032)
- Testing
- NVD-001, Standard of Care
- Where
- 12 sites in Belgium, Czechia and 1 more
- Volunteers
- 48 people
- Sponsor
- Novadip Biosciences
Isthmic Spondylolisthesis
Comparative Study of Anterior vs. Posterior Surgical Treatment for Lumbar Isthmic Spondylolisthesis
The aim of this study is to compare outcomes and cost-effectiveness of anterior versus posterior surgical treatment for lumbar Isthmic Spondylolisthesis.
- Trial name
- I-Spondy (NCT02564705)
- Testing
- Anterior Lumbar Interbody Fusion (ALIF), Posterior Fusion
- Where
- 14 sites in United States, Canada
- Volunteers
- 177 people
- Sponsor
- AOSpine North America Research Network