Clinical trials: Spontaneous Abortions
Missed Abortion
Operative Hysteroscopy and Ultrasound Guided Vacuum Aspiration Versus Blind Vacuum Aspiration for the Treatment of Missed Abortion
The intervention to be evaluated are operative hysteroscopy(group A) and ultrasound guided aspiration(group C) and blinded vacuum aspiration(group B).
- Trial name
- NCT03081104
- Testing
- hystroscopy, ultrasound, Aspiration
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Miscarriage
Womens's Experiences of Pregnancy Loss Aftercare in the Gynecological Emergency
Introduction: Scientific papers on the womens's experiences of pregnancy loss aftercare in the emergency department show that how announcement is made and how much caregivers show empathy to women, help women to face this…
- Trial name
- NCT04190043
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Heavy Metal Toxicity, Spontaneous Abortion
the Association Between Blood's and Urinary Heavy Metal Level in Pregnant Women and the Spontaneous Abortion
The aim of the study was to define the possible association between heavy iron level and the consequence of pregnancy especially spontaneous abortion and missed abortion.
- Trial name
- HMLandSA (NCT03332706)
- Testing
- observation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Preterm Birth, Cervical Incompetence
Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study
The goal of this Phase I clinical trial is to generate proof-of-concept data to demonstrate that a cervical cup in combination with vacuum application will create negative pressure on uterine cervical tissue, thereby creating…
- Conditions
- Preterm Birth, Cervical Incompetence, Cervical Insufficiency, Short Cervix
- Trial name
- NCT05512052
- Testing
- Hannah Cervical Cup (2 mm Delta), Hannah Cervical Cup (4 mm Delta), Hannah Cervical Cup (6 mm Delta)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Galena Innovations, LLC
Miscarriage
Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention
Introduction: Incomplete early miscarriage is defined as early miscarriage with persistent intrauterine material on ultrasound. Intrauterine retention of trophoblastic debris is not an uncommon phenomenon.
- Trial name
- HARET (NCT05789940)
- Testing
- hysteroscopy, Aspiration
- Where
- 4 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Montpellier
Abortion, Missed
Misopristol Versus Pitocin for Second Trimester Abortion
Second trimester abortion can be done surgically or medically. Medical abortion with mifepristone and misopristol is one of the common protocol, but misopristol have high rate side effect.
- Trial name
- NCT00784797
- Testing
- mifepristone and misopristol, mifepristone and oxytocin
- Where
- Israel
- Volunteers
- 145 people
- Sponsor
- Hadassah Medical Organization
Miscarriage
Letrozole Pretreatment With Misoprostol for Second-Trimester Medical Abortion
To compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of pregnancy in second trimester abortion.
- Trial name
- NCT02405156
- Testing
- Letrozole, Misoprostol
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy Complicated by Low Implantation
Intralipid Therapy for Recurrent Implantation Failure and Recurrent Miscarriages: Is it a Hope or Myth?A Randomized Clinical Trial
Both organ-specific and systemic autoimmunity are associated with an increased prevalence of recurrent miscarriage and reproductive failure, rendering the role of the maternal immunological system in fertility a key concept.
- Trial name
- ILRIFRM (NCT01679561)
- Testing
- intralipid
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Recurrent Miscarriage
Investigation of Embryoscopy in Recurrent Pregnancy Loss
The purpose is to test the value of embryoscopy in women with missed abortions after recurrent miscarriages (at least two previous miscarriages) in the past. This project will assess two functions of embryoscopy:- 1.
- Trial name
- NCT00589446
- Testing
- Hysteroscope
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Missed Abortion
Oxytocin Effectiveness in First Trimester Dilatation and Curettage
The aim of this study is to investigate the impact of oxytocin on perioperative blood loss during the D\&C procedure, as well as to assess early and late complications associated with it's use.
- Trial name
- NCT06469203
- Testing
- Oxytocin, Sodium Chloride 0.9% Inj
- Volunteers
- 160 people
- Sponsor
- Assuta Ashdod Hospital
Recurrent Abortion
Sildenafil Citrate and Recurrent Abortion
Two groups of unexplained recurrent spontaneous abortion, each included 65 participants. scheduled randomly into; the study group received Sildenafil Citrate and Placebo group.
- Trial name
- NCT03475160
- Testing
- Sildenafil Citrate vaginal suppositories, Uterine artery Doppler before treatment, Uterine artery Doppler after treatment
- Volunteers
- 130 people
- Sponsor
- Benha University
Pregnancy, Spontaneous Abortions
Study of the Best Blastocyst Post Transfer by aCGH
An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy
- Conditions
- Pregnancy, Spontaneous Abortions, Stillbirth
- Trial name
- NCT01664546
- Testing
- Trophectoderm biopsy
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- University of Buenos Aires
Threatened Miscarriage
Chinese Herbal Medicine (New "Shoutai Wan") and/or Oral Progesterone Intervention Trial for Threatened Miscarriage
Threatened miscarriage is manifested by vaginal bleeding, with or without abdominal pain, while the cervix is closed and the fetus is viable and inside the uterine cavity.
- Trial name
- NCT02633878
- Testing
- Chinese Herbal Medicine (New "Shoutai Wan") plus Oral Progesterone
- Where
- 22 sites in China
- Volunteers
- 1,656 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Infertility
Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Frozen Embryo Transfer on Cycle Outcomes
The present study is designed as a pilot study with 150 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group.
- Trial name
- NCT02355925
- Testing
- intrauterine injection of uhCG, control
- Where
- Iran
- Volunteers
- 180 people
- Sponsor
- Royan Institute
Missed Abortion
Effects of Mandala Coloring in Missed Abortion
This randomized controlled study aims to evaluate the effects of mandala coloring activity on stress, anxiety, pain, and physiological parameters in women diagnosed with missed abortion.
- Trial name
- NCT07420413
- Testing
- Mandala Coloring Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Selcuk University
Missed Abortion
Repeated Doses of Misoprostol for Medical Treatment of Missed Miscarriage
Missed abortion is a condition where the fetus has perished but the miscarriage is not expelled. Women often present at a routine ultrasound or with a slight brownish discharge.
- Trial name
- NCT01615224
- Testing
- misoprostol
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Kristina Gemzell Danielsson
Recurrent Miscarriage
Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages
The purpose of this study is to determine whether sildenafil citrate is effective in improving uterine artery blood flow and oxidative stress in patients with unexplained recurrent miscarriages
- Trial name
- NCT01419392
- Testing
- Sildenafil citrate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Recurrent Miscarriage, First Trimester Abortion
Hydroxychloroquine for Prevention of Recurrent Miscarriage.
Recurrent miscarriage (RM) defined by >=3 consecutive losses affects 1% of fertile couples. Most women have recurrent early loss with a failure of development before 10 weeks' gestation.
- Trial name
- BBQ (NCT03165136)
- Testing
- Hydroxychloroquine
- Where
- 18 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Post-traumatic Stress Disorder, Miscarriage
Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task
This is a randomised controlled trial designed to investigate the impact of a brief-cognitive task based intervention on intrusive memories, mental health symptoms and daily functioning, in women following an early pregnancy loss.
- Conditions
- Post-traumatic Stress Disorder, Miscarriage, Ectopic Pregnancy, Pregnancy Loss
- Trial name
- IMPREL (NCT05039853)
- Testing
- Brief cognitive task-based intervention
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cerclage, Cervical, Cervical Insufficiency
Effectiveness of Cervico-isthmic Cerclage
This study compares the rate of live births before and after cervico-isthmic cerclage in 3 hospitals in the last 10 years. The hypothesis is that cerclage significantly increases the rate of live births in women with cervical…
- Trial name
- CERCEI LB (NCT04722536)
- Testing
- Cervico-isthmic cerclage
- Where
- 3 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon