Clinical trials: Spontaneous Abortions
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Recurrent Pregnancy Loss, Recurrent Miscarriages
Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent Miscarriage
Recurrent pregnancy loss (RPL), commonly referred to as recurrent miscarriage, affects approximately 1-2% of couples attempting to conceive.
- Trial name
- GEM (NCT07724405)
- Testing
- Recombinant G-CSF
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Fakih IVF Fertility Center
Infertility, Recurrent Pregnancy Loss
Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis
We propose to perform a clinical randomized trial to evaluate the effect of blastocyst biopsy and whole chromosome analysis by Next Generation Sequencing (NGS) in comparison to standard Assisted Reproductive Technologies (ART)…
- Trial name
- NCT01946945
- Testing
- Next Generation Sequencing after Blastocyst biopsy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Reprogenetics
Endometriosis, Miscarriage
Endometriosis and Risk of Miscarriage
The aim of this study is to compare the rate of miscarriage at first spontaneous pregnancy among women with endometriosis with the rate of miscarriage at first spontaneous pregnancy among women without endometriosis.
- Trial name
- NCT03354780
- Testing
- Survey on first pregnancy after endometriosis diagnosis, Survey on first pregnancy
- Volunteers
- 844 people
- Sponsor
- Endometriosis Treatment Italian Club
Pregnancy
First Trimester of Pregnancy: Impact of a History of Miscarriage on Women's Stress
Miscarriage is the spontaneous termination of pregnancy before 22 weeks of amenorrhea. The most frequent complication of pregnancy, it represents 10 to 25% of pregnancies and affects one in four women.
- Trial name
- Stress-FC (NCT04841486)
- Testing
- Data collection
- Where
- France
- Volunteers
- 93 people
- Sponsor
- Université de Reims Champagne-Ardenne
Preterm Birth, Threatened Preterm Labor
Cervical Softening and the Prediction of Preterm Birth
Currently, transvaginal cervical length measurement is used to screen in asymptomatic pregnant women with a history of PTB. In symptomatic women, presenting with threatened PTB cervical length in combination with the fibronectin…
- Conditions
- Preterm Birth, Threatened Preterm Labor, Premature Birth, Premature Labor
- Trial name
- STIPP (NCT05477381)
- Testing
- Measurement of cervical stiffness by Pregnolia Device
- Where
- Netherlands
- Volunteers
- 390 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Pregnancy Loss, Early, Major Depression
Effect of Participating in a Study of Causes of Pregnancy Loss on Mental Health Outcomes: A Target Trial Emulation Using the COPL Cohort and Danish National Registries
Pregnancy loss is the most common severe pregnancy complication and is associated with significant mental health sequelae, including depression and anxiety.
- Conditions
- Pregnancy Loss, Early, Major Depression, Anxiety, Stress (Psychology)
- Trial name
- NCT07684677
- Testing
- COPL participation
- Where
- Denmark
- Volunteers
- 30,000 people
- Sponsor
- Amager Hospital
Recurrent Abortion
Laparoscopic Transabdominal Cerclage: New Approach
A 5-mm non-absorbable Mersilene polyester suture, with adjacent partially straightened blunt needles, is introduced into the abdominal cavity through the 5-mm trocar.
- Trial name
- NCT02457377
- Testing
- laparoscopic cerclage
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ahmed Maged
Abortion
Comparative Psychiatric Problems Between First and Second Trimester Miscarriage
Description of the psychiatric impact of miscarriage on women.
- Trial name
- NCT06742632
- Testing
- Symptoms checklist-90
- Where
- Egypt
- Volunteers
- 155 people
- Sponsor
- Assiut University
Chromosome Translocation, Genetic Disorders in Pregnancy
Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst
Blastocysts derived from patients seeking infertility treatment were generated by in vitro fertilization and embryo culture as previously described, and were evaluated using the Gardner system.
- Conditions
- Chromosome Translocation, Genetic Disorders in Pregnancy, Recurrent Miscarriage
- Trial name
- NCT05216068
- Testing
- NGS
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Missed Abortion, Incomplete Abortion
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
During the recent decades the need for surgical evacuation of the uterus in early miscarriages and incomplete miscarriages has been questioned.
- Conditions
- Missed Abortion, Incomplete Abortion, Uterine Gestational Residua, Uterine Artery Doppler
- Trial name
- NCT01775917
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Carmel Medical Center
Recurrent Spontaneous Abortion
Difference Between Mean Gestational Sac Diameter and Crown-rump Length as a Marker of First-trimester Pregnancy Outcome in Patients With Recurrent Spontaneous Abortion
Objective: To determine the effect and predictive value of the difference between the mean gestational diameter (mGSD) sac and crown-rump length (CRL) of the first trimester on the pregnancy outcomes of patients with recurrent…
- Trial name
- mGSD-CRL& RSA (NCT06081556)
- Testing
- ultrasonic testing
- Where
- China
- Volunteers
- 256 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Abortion, Habitual
Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss
With this clinical trial the investigators will analyze whether the rate of pregnancy losses before the 24th week of gestation can be reduced by dalteparin treatment in habitual aborters.
- Trial name
- NCT00400387
- Testing
- Fragmin P Forte (dalteparin sodium), Multivitamin supplement
- Where
- 12 sites in Austria, Germany
- Volunteers
- 449 people
- Sponsor
- University of Jena
Spontaneous Abortion
Knowledge, Attitude and Practices of Flemish Midwifes Regarding Spontaneous Abortion
KAP-study in Flemish midwives with intramural employment
- Trial name
- KAP-abortion (NCT02657200)
- Testing
- survey
- Where
- Belgium
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- VakgroepVolksgezondheidEnEerstelijnszorg
Abortion, Spontaneous, Abortion in First Trimester
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic.
- Conditions
- Abortion, Spontaneous, Abortion in First Trimester, Pain Uterus, Abortion Early
- Trial name
- NCT03636451
- Testing
- 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block, 20cc 1% lidocaine with 2 units of vasopressin paracervical block
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Miscarriage, Misoprostol
Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage
The miscarriage is one of the adverse outcomes of pregnancy and is responsible for stress and anxiety of the couple. there are different types of miscarriages.missed miscarriage also known as early fetal demise is one of the type…
- Trial name
- NCT04604366
- Testing
- misoprostol
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Incomplete Abortion
Sublingual Misoprostol for the Treatment of Incomplete Abortion: Operations Research
This study will investigate the use of misoprostol for first-line treatment of incomplete abortion at tertiary hospitals in Myanmar.
- Trial name
- NCT02707653
- Testing
- Misoprostol
- Where
- 2 sites in Burma
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Incomplete Abortion
Treatment of Incomplete Abortion With 600 Mcg Oral Misoprostol Compared to Standard Surgical Treatment
This study aims to compare the efficacy, side effects profile and acceptability of a single dose of 600mcg misoprostol taken orally compared to standard surgical treatment as per local protocols for the treatment of incomplete…
- Trial name
- NCT00674232
- Testing
- 600 mcg misoprostol, Surgical treatment
- Where
- 3 sites in Ecuador, Venezuela
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects