Clinical trials: Spontaneous Abortions
Down Syndrome
Non Invasive Prenatal Testing of Down Syndrome
This is a randomized controlled trial in women at risk following combined prenatal screening for Down Syndrome. Women will be asked about their preferences between NIPT and routine prenatal diagnosis based on a dedicated…
- Trial name
- SAFE 21 (NCT02127515)
- Testing
- Non Invasive Prenatal Testing, Invasive Prenatal Testing
- Where
- France
- Volunteers
- 2,111 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Infections, Papillomavirus
Post-marketing Safety Study to Assess the Risk of Spontaneous Abortions in Women Exposed to Cervarix Residing in UK
This study will assess the risk of spontaneous abortion during weeks 1-23 and weeks 1-19 of gestation, respectively, and other pregnancy outcomes, in an exposed cohort, i.e.
- Trial name
- NCT01905462
- Testing
- Data Collection, Cervarix
- Where
- United Kingdom
- Volunteers
- 1,046 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Miscarriage
Management of Women With an Incomplete Miscarriage
Miscarriage is defined as the spontaneous loss of a pregnancy before 24 weeks' gestation, that is, before the fetal viability. The clinical signs of miscarriage are usually vaginal bleeding associated abdominal pain and cramping…
- Trial name
- NCT03148561
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Birth Defects, Miscarriages
Pesticides--Health Fertility and Reproductive Risk
This project is designed to establish whether pesticides or other environmental agents have a role in the excess birth defects identified in the Red River Valley of Minnesota.
- Conditions
- Birth Defects, Miscarriages, Cancer
- Trial name
- NCT00015561
- Where
- United States
- Volunteers
- 1,803 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Habitual Abortion
Use of G-CSF for the Treatment of Unexplained Recurrent Miscarriage
In order to investigate the effectiveness of G-CSF in preventing embryo demise, the investigators administered this cytokine to women with recurrent miscarriage in a randomized controlled study compared to women treated with…
- Trial name
- NCT00772122
- Testing
- G-CSF, saline solution
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Florence
Pregnancy Related, Cervical Insufficiency
Cervical Stiffness Measurement in Cervical Insufficiency
The goal of this cross sectional study is to evaluate the differences in cervical stiffness between patients who present for cerclage placement versus normal pregnancies.
- Conditions
- Pregnancy Related, Cervical Insufficiency, Preterm Birth
- Trial name
- NCT04158401
- Testing
- Pregnolia
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Unexplained Recurrent Miscarriage
Hydroxychloroquine and Unexplained Recurrent Miscarriage
Recurrent miscarriage affects women of childbearing age worldwide. Vascular endothelial dysfunction and immunological impairment are associated with recurrent miscarriage To date, there is no effective or optimal therapeutic…
- Trial name
- NCT04228263
- Testing
- Hydroxychloroquine, Folic Acid, Low-dose aspirin
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Assiut University
Miscarriage, Stillbirth
Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi
This study, to be carried out immediately following an emergency, reactive cholera vaccination campaign in Nsanje District, Malawi, will be a cohort study to estimate the safety of killed oral cholera vaccine (OCV), in pregnant…
- Conditions
- Miscarriage, Stillbirth, Cholera
- Trial name
- NCT02499172
- Testing
- Shanchol
- Where
- United States
- Volunteers
- 2,758 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Recurrent Miscarriage
Use of Platelet Indices for Prediction of Recurrent Miscarriage
Platelet indices might be a marker for platelet activation, and thus could predict thrombosis. This might be the cause in some cases of recurrent miscarriage.
- Trial name
- NCT03710226
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Rania Hassan Mostafa
Recurrent Miscarriage
Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies
Recurrent miscarriage (RM) is traditionally defined as three or more consecutive miscarriages occurring before 20 weeks post-menstruation.
- Trial name
- LMWH-APAN (NCT01608347)
- Testing
- LMWH+Folic acid, Folic Acid
- Volunteers
- 228 people
- Sponsor
- Omar Mamdouh Shaaban
Infertility, Recurrent Pregnancy Loss
Preimplantation Genetic Diagnosis Using Blastocyst Biopsy and Array CGH
The investigators propose to perform a clinical randomized trial to evaluate the effect of single embryo (blastocyst) transfer (SET) with array CGH for the evaluation of the complete chromosome complement of the blastocyst in…
- Trial name
- NCT01546350
- Testing
- PGD
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Reprogenetics
Abortion, Recurrent
Role of Hypersensitivity to Female Sex Hormones in Women With Unexplained Recurrent Pregnancy Loss
The EVE- technology is intended for determination of intolerance or sensitivity to female sex hormones among women with hormone-related conditions and for further treatment by desensitization procedure inducing a tolerance to the…
- Trial name
- NCT01175759
- Testing
- Skin test panel
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- EVE Medical Systems Ltd.
Recurrent Miscarriage, Infertility
Iron Status in Female Infertility and Recurrent Miscarriage
Multiple studies suggest a link between the iron status and the development of the endometrium. Therefore, a sufficient iron supply seems to relevant for female fertility and reproduction.
- Conditions
- Recurrent Miscarriage, Infertility, Iron-deficiency
- Trial name
- NCT05034250
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Infertility
Incidence of Early Pregnancy Loss in Patients With Unexplained Infertility
Unexplained fertility could be partly caused by a higher incidence of early pregnancy loss in this group. 65 women with unexplained infertility and 65 healthy controls will collect daily urine samples form the luteal phase.
- Trial name
- UNEXPLAINED (NCT01015690)
- Where
- Netherlands
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Endometriosis, Pregnancy Complications
Impact of Endometriosis on Pregnancy and Delivery - a Retrospective Cohort Study
Purpose: To study the impact of endometriosis on subsequent pregnancy and delivery. Methods: retrospective analysis by questionnaire / interview of cases (endometriosis laparoscopically removed / child wish) vs.
- Conditions
- Endometriosis, Pregnancy Complications, Delivery Complication, Complication
- Trial name
- NCT04664335
- Testing
- questionnaire
- Where
- Germany
- Volunteers
- 1,762 people
- Sponsor
- University Hospital Muenster
Spontaneous Abortion
Comprehensive Assessment of Risks for Miscarriage.
This study aims to determine the role of serum biomarkers and placental bloodflow in the comprehensive evaluation of the risk for spontaneous abortion
- Trial name
- MIS-CARE (NCT04456660)
- Testing
- Markers of ultrasound, Immunologic factors, Serum factors
- Where
- Bulgaria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Orthogyn Medical Center, Bulgaria
Thrombophilia, Thyroid Autoimmunity
Thrombophilia and Thyroid Autoimmunity in Implantation Failure and Recurrent Miscarriage
This study was designed to evaluate the incidence of both, inherited and adquired thrombophilia, and thyroid autoinmunity in unknown infertility (UI), implantation failure (IF) and recurrent miscarriage (RM).
- Trial name
- NCT00485446
- Testing
- blood analysis
- Where
- Spain
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Missed Abortion
Termination Of Anembryonic Pregnancy
Anembryonic pregnancy is a leading cause of early miscarriage. The American Pregnancy Association estimates that blighted ovum causes approximately 50 percent of all first-trimester miscarriages.
- Trial name
- NCT02573051
- Testing
- Misoprostol, Isosorbide mononitrate
- Where
- Egypt
- Sponsor
- Assiut University