Clinical trials: Spotting
Isthmocele, Post-menstrual Spotting Bleeding
Can Intrauterine Levonorgestrel Releasing Device Be a Treatment Option for Postmenstrual Spotting in Isthmocele
it was planned to investigate the treatment effect of levonorgestrel releasing intrauterine device in patient with isthmocele who were suffering from postmenstrual spotting bleeding and who had no desire for fertility.
- Conditions
- Isthmocele, Post-menstrual Spotting Bleeding, Pelvic Pain
- Trial name
- NCT04872244
- Testing
- usage of mirena ( levonorgestrel releasing intrauterine device) in isthmocele, Levonorgestrel Drug Implant Product
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Iron Deficiency Anemia, Abnormal Uterine Bleeding
Tolerability of Iron Therapy in Women With AUB
Telephone surveys of female patients using liposomally-bound iron and traditional iron sulphate preparations for the management of iron deficiency anemia to determine gastrointestinal tolerability.
- Trial name
- NCT04915196
- Testing
- Liposomally-bound Iron
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Observational Study, Dydrogesterone
Observational Study of Dydrogesterone in Cycle Regularization
Dydrogesterone has been widely used worldwide for various gynecological and obstetric indications: Dydrogesterone is effective in cycle regulation treatment.
- Conditions
- Observational Study, Dydrogesterone, Irregular Menstrual Cycle, Abnormal Uterine Bleeding
- Trial name
- NCT02029144
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Fudan University
Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
Cervical Ripening Before Endometrial Biopsy in Abnormal Uterine Bleeding Using Sublingual Misoprostol
Abnormal uterine bleeding is common in Thai women. Fractional curettage is an diagnostic procedure of this condition. Traditionally, fractional curettage is performed under local anesthesia such as paracervical nerve block or…
- Trial name
- NCT01762319
- Testing
- Misoprostol, Vitamin B6
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Abnormal Uterine Bleeding, Postmenopausal Bleeding
Pipelle Versus Karman Endometrial Biopsy Under Standardized Paracervical Block
Endometrial biopsy is a commonly used outpatient procedure to evaluate abnormal uterine bleeding and postmenopausal bleeding. Different sampling methods are available, but their diagnostic adequacy and patient experience may…
- Trial name
- PB-EMB (NCT07366814)
- Testing
- Pipelle Endometrial Biopsy, Karman Cannula Endometrial Biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dysmenorrhea, Metrorrhagia
Cooperative Adenomyosis Network
To set up a Cooperative Network by enrolling 5000 patients with Adenomyosis(AM) from multiple centers.Based on the Network platform and Database,the investigators try to explore the diagnostic strategies for AM and carry out…
- Conditions
- Dysmenorrhea, Metrorrhagia, Infertility, Female, Pathology
- Trial name
- CAN (NCT03230994)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Peking Union Medical College Hospital
Abnormal Uterine Bleeding
Transvaginal Ultrasound in Women With Abnormal Uterine Bleeding
The objective of this study is to investigate the role of transvaginal ultrasound in detecting endometrial hyperplasia and endometrial cancer in women aged more than 35 presenting with abnormal uterine bleeding.
- Trial name
- NCT01786798
- Testing
- Transvaginal sonography
- Where
- Thailand
- Volunteers
- 560 people
- Sponsor
- Chulalongkorn University
Abnormal Uterine Bleeding
D-chiro-inositol and AUB
Patients with AUB will undergo 6-month treatment with D-chiro-inositol and will fill in questionnaires on AUB, with the evaluation of hormonal serum levels.
- Trial name
- NCT06398145
- Testing
- D-chiro-inositol and lactalbumin (high dose), D-chiro-inositol and lactalbumin (low dose)
- Volunteers
- 20 people
- Sponsor
- University Of Perugia
Pain
Fundal Block in Pre-menopausal Women to Reduce Pain During Outpatient-based Endometrial Ablation (FUNDAL-PAIN)
The objective of this study is to assess the efficacy of a fundal block in reducing women's perception of pain during NovaSure endometrial ablation (EA) in an outpatient-based setting.
- Trial name
- FUNDAL-PAIN (NCT04249063)
- Testing
- Xylocaine 1 % and Normal Saline, Normal Saline
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Abnormal Uterine Bleeding, Analgesia
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.
- Conditions
- Abnormal Uterine Bleeding, Analgesia, Paracervical Block
- Trial name
- NCT06653400
- Testing
- paracervical block, Lidocaine, ketorolac
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Uterine Fibroid
UA Versus UAE in Treatment of Fibroids
Study objective: To prove that Ulipristal acetate is an effective line of management for uterine fibroids by causing a significant decline in fibroid volumes resulting in a substantial relief of fibroid-related symptoms, and to…
- Trial name
- NCT04832906
- Testing
- Ulipristal Oral Tablet, Uterine artery embolization
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital
Metrorrhagia
Pilot Study of Femring Estrogen Supplementation During Depo-Provera Initiation
Many women choose Depo-Provera for birth control because it is easy to use and very effective. However, a significant number of Depo-Provera users experience irregular bleeding during the first 90 days.
- Trial name
- NCT00563576
- Testing
- Femring®, DepoProvera ®
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Columbia University
Abnormal Uterine Bleeding
Patient Satisfaction With Initial Phone Call Versus Office Visit Following Minimally Invasive Hysterectomy, a Randomized Controlled Trial.
Patients will be randomized to clinic or telephone follow up after outpatient TLH. surveys will document patient satisfaction.
- Trial name
- NCT03809468
- Testing
- phone call follow up
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Menorrhagia, Abnormal Uterine Bleeding
Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding
The goal of this clinical trial is to determine if calcium dobesilate is an effective alternative to tranexamic acid for treating menorrhagia in women aged 18 to 39 years.
- Trial name
- NCT06763094
- Testing
- Calcium dobesilate (Doxium), Tranexamic Acid
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Cesarean Section Niche and Abnormal Uterine Bleeding
Prevalance of Cesarean Section Niche in Patients With Abnormal Uterine Bleeding
Prevalance of Cesarean section niche in patients with abnormal uterine bleeding
- Trial name
- NCT05067296
- Testing
- By TVS
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Mahmoud Ramadan Hafez
Menorrhagia
Chances for Success of CavatermTM Surgery as a Function of Uterus Probe Length
CavatermTM is a second-generation thermal balloon ablation device in the management of menorrhagia. The purpose of this study is to investigate the success (questionnaire) of CavatermTM dependent on uterus probe length…
- Trial name
- NCT01436903
- Testing
- Thermal Balloon Endometrial Ablation
- Where
- Austria
- Volunteers
- 290 people
- Sponsor
- Medical University of Vienna