Clinical trials: Stability of Microbiome
Health Adults, Stability of Microbiome
Westlake Frequent-sampling Cohort 2
This observational follow-up study extends a previously completed 15-day intensive longitudinal study (WeF) of the gut microbiome in healthy adults.
- Trial name
- WeF2 (NCT07606885)
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Westlake University
Skin Pigmentation
Prospective Evaluation of Topical Almond Oil vs Hydroquinone
The purpose of this study is to analyze facial pigmentation and skin microbiome changes after topical almond oil application, compared to the use of topical hydroquinone.
- Trial name
- NCT04875715
- Testing
- Almond Oil, Hydroquinone Topical
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Oral Microbiota, Long Term Sample Stability
Long-Term Stability of Oral Microbiome Samples
Background: The human biome is the collection of microbial genes found in and on the body. It has been associated with many health conditions. But certain factors might affect the findings from microbiome studies.
- Trial name
- NCT03068546
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Healthy
A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects
This exploratory, randomized, double-blind, placebo-controlled study aims to explore the effect of novel glycans on nitrogen metabolism in the gut in healthy subjects using a stable isotope.
- Trial name
- NCT04603378
- Testing
- KB195, Polydextrose, Pullulan
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kaleido Biosciences
Necrotising Enterocolitis, Late-Onset Neonatal Sepsis
Characterization of Intestinal Microbiota Stability in Preterm Born Neonates
Study around very-low birthweight preterm infants at high risk of developing necrotizing enterocolitis (NEC) or late-onset sepsis (LOS).
- Trial name
- NEC (NCT04792918)
- Where
- 2 sites in Switzerland
- Volunteers
- 81 people
- Sponsor
- Emma Marie Caroline Slack
Vaginal Microbiome
The Maggie Project: Exploring the Origin and Heredity of the Vaginal Microbiome
The vaginal microbiome plays a crucial role in women's health and reproduction, impacting not only women but also their partners and children. However, its ecology and primary colonizers are not well understood.
- Trial name
- Maggie (NCT06912126)
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Dry Eye Syndromes
Ocular Surface Microbiome
The purpose of this study is to collect samples from the surface of eyelids to try to grow and identify bacteria or fungus that might be present, and to try to understand why people have dry eye symptoms.
- Trial name
- NCT02298881
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Impacted Third Molar Tooth
Impact of Antibiotic Treatment and Extraction on the Oral Micro Biome
This is a prospective, longitudinal, observational, cohort study investigating young adults undergoing surgical extraction of a wisdom tooth with and without antibiotics post-operatively.
- Trial name
- NCT02951676
- Testing
- Extraction
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy
Whole Grain and Fiber Addition Study
The human gut microbiota is the complex community of bacteria that reside within the human gastrointestinal tract. This community plays an important role in supporting normal immune function and digestion.
- Trial name
- NCT03623308
- Testing
- Fiber cereal
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Health Adults, Stability of Microbiome
Westlake Frequent-sampling Cohort
This intensive longitudinal study investigates the day-to-day stability and natural fluctuations of the gut microbiome in healthy adults over a 15-day period.
- Trial name
- WeF (NCT07460687)
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Westlake University
Total Hip Arthroplasty
Corail Stability at 5-Years Post-Total Hip Arthroplasty
Total hip arthroplasty (THA) is the mainstay, definitive management for end-stage hip osteoarthritis. Despite improvements of surgical and patient factors, prosthesis-related complications continue to increase in number.
- Trial name
- NCT05893563
- Testing
- Standard Post-Operative Clinic Visit, Study-Specific Outcomes
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Microbiota
Stability of the Microbiome in IBD and IBS
In this study the investigators aim to investigate the changes of the intestinal microbiome in three different cohorts (IBD, IBS, healthy) after applying the uniform disruptive factor of osmotic diarrhea induced by macrogol.
- Trial name
- NCT03395548
- Testing
- Macrogol
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz