Clinical trials: Stable Coronary Heart Disease
Hypertension, Blood Pressure
Long-term Accuracy and Stability of Blood Pressure Measurements From a Smartwatch: Prospective Validation Study
The aim of the study is to perform an experimental validation of the long-term accuracy of blood pressure measurement using the Samsung Galaxy Smartwatch
- Trial name
- BPLONG (NCT06098092)
- Testing
- Long-term non-invasive Blood pressure monitoring
- Where
- 2 sites in Czechia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Coronary Heart Disease, Angina Pectoris
Aspirin Non-responsiveness and Clopidogrel Endpoint Trial.
In the ASCET study, 1000 patients with documented coronary heart disease will be randomized to either continued treatment with aspirin 160 mg/d or change to clopidogrel 75mg/d.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Atherosclerosis
- Trial name
- ASCET (NCT00222261)
- Testing
- aspirin, clopidogrel
- Where
- Norway
- Volunteers
- 1,001 people
- Sponsor
- Ullevaal University Hospital
Platelet Reactivity
Low-dose of Ticagrelor and Standard-dose Clopidogrel on Platelet Effects in Chinese Patients With Stable CAD.
Ticagrelor has been demonstrated to provide a more rapid and more powerful inhibition of platelet aggregation compared with clopidogrel in coronary artery disease (CAD) patients.
- Trial name
- NCT03679091
- Testing
- low-dose ticagrelor, Clopidogrel
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents
There has been little research on neointimal coverage and malapposition after BES implantation using OCT in human coronary artery. Furthermore, specific drug may possibly influence the vascular healing after stent implantation.
- Trial name
- NCT01502904
- Testing
- Sirolimus-eluting stent, Biolimus-eluting stents, pravastatin 20mg/day after DES implantation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Cardiovascular Diseases
Comparing Multicomponent and Isometric Multicomponent Training: Impact on Fitness, Health, and Life Quality in Heart Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an isometric multicomponent training program (IMCT) can improve physiological, physical…
- Trial name
- NCT06819098
- Testing
- Multicomponent Training Protocol, Isometric Multicomponent Training
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Bari Aldo Moro
Coronary Artery Disease, Microcirculation
The ImPact of Trimetazidine on MicrOcirculation After Stenting for Stable Coronary Artery Disease
The study should enrol 50 patients with stable coronary artery disease scheduled for elective percutaneous coronary intervention of single, de novo lesion of native coronary artery.
- Conditions
- Coronary Artery Disease, Microcirculation, Vascular Resistance
- Trial name
- PATMOS (NCT02107144)
- Testing
- trimetazidine
- Where
- Serbia
- Volunteers
- 71 people
- Sponsor
- Clinical Hospital Center Zemun
Coronary Artery Disease, Ischemic Heart Disease
Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold
To evaluate the safety, performance and efficacy of the bioresorbable vascular scaffold (BVS) system in patients with coronary artery disease
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Stable Angina, Unstable Angina
- Trial name
- CSI-Ulm-BVS (NCT02162056)
- Testing
- use of bioresorbable vascular scaffolds
- Where
- Germany
- Volunteers
- 326 people
- Sponsor
- University of Ulm
Heart Failure
Effectiveness of a Diuretic Algorithm in Clinical Stability in Heart Failure Patients
One of the challenges in treating patients with heart failure (HF) is achieving clinical stability and reducing the hospital readmission rate.
- Trial name
- NCT02068937
- Testing
- Furosemide and Phone contact, Furosemide
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiovascular Diseases, Atherosclerosis
Aspirin Dose and Atherosclerosis in Patients With Heart Disease
The purpose of the study is to test higher versus lower doses of aspirin on markers of atherosclerosis in patients who have had a heart attack.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Myocardial Infarction
- Trial name
- TAD (NCT00272337)
- Testing
- Aspirin
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Angina Pectoris
Efficacy and Safety of Ivabradine on Top of Atenolol in Stable Angina Pectoris
To test whether ivabradine when given in combination with atenolol is able to improve the exercise tolerance of patients with stable angina pectoris
- Trial name
- ASSOCIATE (NCT00202566)
- Testing
- Ivabradine
- Where
- Canada
- Volunteers
- 750 people
- Sponsor
- Institut de Recherches Internationales Servier
Coronary Artery Disease
Clopidogrel/Aspirin Interaction Study
This study will explore the effect of different doses of aspirin on the effects of double-dose or standard dose clopidogrel.
- Trial name
- INTERACTION (NCT01102439)
- Testing
- Clopidogrel, Aspirin
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Population Health Research Institute
Chronic Stable Angina, Refractory Angina
Wave Crossover ECP Study for Simplified Therapy
The purpose of this study is to demonstrate substantial equivalence between Pression's Wave PRO System and a commercially available predicate ECP device to support a U.S. 510(k) submission for the Wave PRO System.
- Trial name
- WaveCRESST (NCT06571370)
- Testing
- External Counterpulsation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pression
Chronic Stable Heart Failure
Matrix Metalloproteinase (MMP) in Heart Failure
The purpose of this study is to evaluate the production of MMP in failing hearts.
- Trial name
- NCT00663494
- Volunteers
- 22 people
- Sponsor
- Tottori University Hospital
Myocardial Ischemia
Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina
The objective of study is to compare the anti-ischemic efficacy and safety profiles of once daily amlodipine or isosorbide-5-mononitrate in the treatment of stable asymptomatic and symptomatic myocardial ischemia
- Trial name
- ANISSA (NCT00143195)
- Testing
- Amlodipine, iso- 5 - mononitrate, Blood tests
- Where
- 12 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postmenopausal Women, Stable Angina Pectoris
Coronary Artery Disease (CAD) in Postmenopausal Women
Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.
- Trial name
- FEMCAD (NCT00763464)
- Testing
- stress-echocardiography, stress-MRI
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Coronary Disease, Ventricular Dysfunction, Left
The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction
The aim of this study is to test whether ivabradine is able to reduce cardiovascular events when given to patients with coronary artery disease and impaired heart function.
- Trial name
- NCT00143507
- Testing
- Ivabradine
- Where
- United Kingdom
- Volunteers
- 10,917 people
- Sponsor
- Institut de Recherches Internationales Servier
Coronary Artery Disease
A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin
The purpose of this study is to see how Ticagrelor, a new oral reversible anti-platelet medication, affects platelets. Anti-platelet agents are medications that block the formation of blood clots by preventing the clumping of…
- Trial name
- NCT00528411
- Testing
- Ticagrelor Tablets, Clopidogrel (over encapsulated) capsule, Aspirin Tablets
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 123 people
- Sponsor
- AstraZeneca
Stable Coronary Artery Disease (CAD), Myocardial Infarction
Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients
THis study is intended to provide contemporary data on the burden of disease in patients 1 to 3 years post-MI, including a description of patient characteristics, current treatment patterns, rate of major CV events, and…
- Trial name
- TIGRIS (NCT01866904)
- Where
- 309 sites in United States, Argentina and 23 more
- Volunteers
- 9,284 people
- Sponsor
- AstraZeneca
Coronary Arterial Disease (CAD), Angina (Stable)
Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCA
The goal of this clinical trial is to learn whether beta-blockers can improve coronary blood flow and reduce resistance in patients with angina and no obstructive coronary arteries (ANOCA).
- Conditions
- Coronary Arterial Disease (CAD), Angina (Stable), Microvascular Circulation
- Trial name
- BEACON (NCT06864234)
- Testing
- Saline (NaCl), Metoprolol Tartrate
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- VZW Cardiovascular Research Center Aalst
Chronic Stable Angina, Coronary Artery Disease
Safety of Amiodarone and Ranolazine Together in Patients With Angina
Ranolazine is an effective and remarkably safe agent for the treatment of patients with chronic stable angina, but its inhibition of voltage gated potassium channels and electrocardiogram (EKG) corrected QT (QTc) prolongation…
- Conditions
- Chronic Stable Angina, Coronary Artery Disease, Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- SARA (NCT01558830)
- Testing
- ranolazine
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cardiovascular Consultants of Nevada