Clinical trials: Stable Coronary Heart Disease
Chronic Stable Angina
Danhong Injection in the Treatment of Chronic Stable Angina
The purpose of this study is to evaluate the effect of Danhong Injection on the relief of angina with the use of the Seattle Angina Questionnaire among patients with stable angina patients
- Trial name
- NCT01681316
- Testing
- Danhong injection, Standard medical care
- Where
- 31 sites in China
- Volunteers
- 920 people
- Sponsor
- China Academy of Chinese Medical Sciences
Stable Angina Pectoris
Cardiogoniometry for Early Diagnosis of Coronary Artery Disease Symptomatik
The register study CGM@CAD will examine whether cardiogoniometry can provide additional information concerning the indication for a diagnostic coronary angiography and if so, which additional value it has.
- Trial name
- NCT01174680
- Testing
- cardiogoniometry
- Volunteers
- 43 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Cardiovascular Disease
Cardiovascular Inflammation Reduction Trial
The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic…
- Trial name
- CIRT (NCT01594333)
- Testing
- Methotrexate
- Where
- 470 sites in United States, Canada and 1 more
- Volunteers
- 4,786 people
- Sponsor
- Brigham and Women's Hospital
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Chronic Stable Angina, Refractory Angina
Wave Crossover ECP Study for Simplified Therapy
The purpose of this study is to demonstrate substantial equivalence between Pression's Wave PRO System and a commercially available predicate ECP device to support a U.S. 510(k) submission for the Wave PRO System.
- Trial name
- WaveCRESST (NCT06571370)
- Testing
- External Counterpulsation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pression
Ventricular Tachycardia, Coronary Artery Disease
Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy
The main objective of this study is to compare the time from randomization to the first recurrence of any ventricular tachycardia (VT) in patients undergoing VT ablation (for stable VTs) and substrate ablation (for unstable VTs)…
- Conditions
- Ventricular Tachycardia, Coronary Artery Disease, Left Ventricular Dysfunction
- Trial name
- VTACH (NCT00919373)
- Testing
- Substrate modification, VT ablation, ICD Implantation
- Where
- 16 sites in Czechia, Denmark and 2 more
- Volunteers
- 110 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, Coronary Stenosis
The Flash FFR Ⅱ Study
The overall purpose of Flash FFR Ⅱ is to investigate whether coronary angiography-derived fractional flow reserve (caFFR), compared with fractional flow reserve (FFR) measured by a pressure wire, has non-inferior clinical effect…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Myocardial Ischaemia, Coronary Circulation
- Trial name
- NCT04575207
- Testing
- caFFR, FFR
- Where
- 13 sites in China
- Volunteers
- 2,132 people
- Sponsor
- Peking University First Hospital
Valvular Heart Disease
Pre-habilitation of Patients Scheduled for Cardiac Valve Surgery
Cardiac rehabilitation (CR) is an integral part of cardiovascular disease management incorporating aspects of scientifically constructed appropriate physical exercise.
- Trial name
- NCT03571906
- Testing
- Tele - Cardiac Pre-Rehabilitation
- Volunteers
- 25 people
- Sponsor
- Sheba Medical Center
Angina, Stable Ischemic Heart Disease
LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions
To establish the effectiveness and tolerability of standard of care anti-anginal treatment (beta-blocker and calcium channel blocker medications) in older adults with symptomatic Stable Ischemic Heart Disease (SIHD) and multiple…
- Trial name
- LIVEBETTER (NCT05786417)
- Testing
- Clinician Discretion, Beta blocker, Calcium channel blocker
- Where
- 10 sites in United States
- Volunteers
- 741 people
- Sponsor
- Yale University
Chronic Obstructive Pulmonary Disease
A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With COPD
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04045418
- Testing
- Laser doppler
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Chinese Medical University
Non-ST Segment Elevation Myocardial Infarction, Unstable Angina Pectoris
Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI
This randomized, open label, controlled, parallel group study is designed to test whether 2-day high dose atorvastatin administration before PCI and 30-day continuous intensive atorvastatin treatment is superior to usual care, in…
- Conditions
- Non-ST Segment Elevation Myocardial Infarction, Unstable Angina Pectoris, Stable Angina Pectoris
- Trial name
- ISCAP (NCT01293097)
- Testing
- Atorvastatin, Statin
- Where
- China
- Volunteers
- 2,884 people
- Sponsor
- Peking University First Hospital
Coronary Artery Disease
Prasugrel/Clopidogrel Maintenance Dose Washout Study
The primary objective of the study is to describe the cumulative proportion of participants who return to baseline platelet P2Y12 receptor function over time (up to 12 days post last maintenance dose) following discontinuation of…
- Trial name
- NCT01014624
- Testing
- Prasugrel, Clopidogrel
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Daiichi Sankyo
Coronary Artery Disease, Coronary Arteriosclerosis
Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease
This study investigates whether chronic heart rate reduction with ivabradine (Procoralan®, Servier, France) affects aortic compliance and endothelial function in patients with chronic stable coronary artery disease.
- Trial name
- NCT01768585
- Testing
- Ivabradine
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Saarland
Chronic Obstructive Pulmonary Disease
A Study on the Heat Transport Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04046640
- Testing
- Infrared thermal imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang Chinese Medical University
Heart Diseases, Heart Failure
Mindfulness & Stress Management Study for Cardiac Patients
The guideline-recommended standard of care for patients who have experienced a heart attack, heart failure, or other coronary event or procedure is exercise-based cardiac rehabilitation (CR).
- Conditions
- Heart Diseases, Heart Failure, Myocardial Infarction, Chronic Stable Angina
- Trial name
- NCT02722213
- Testing
- Mindfulness-Based Stress Reduction (MBSR).
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Minnesota
Acute Myocardial Infarction, Stable Angina
Development and Efficacy Evaluation of Integrated Chronic Care and Health Promotion Model for Patients With Coronary Artery Disease in Taiwan
The hypothesis of this project is to examine whether the integrated health care program as the intervention group can reduce the recurrence and mortality of coronary artery-related diseases than the traditional one as the…
- Trial name
- NCT01357096
- Testing
- Integrated health care team, Traditional group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Heart Failure
A Study of CK-1827452 Infusion in Stable Heart Failure
This study will assess the safety, tolerability, and pharmacodynamics of CK-1827452 infusion in patients with stable heart failure.
- Trial name
- NCT00624442
- Testing
- CK-1827452
- Where
- 17 sites in United States, Georgia and 2 more
- Volunteers
- 45 people
- Sponsor
- Cytokinetics
Dyspnea
Inspiratory Muscle Training in Stroke Patients With Stable Congestive Heart Failure: a Prospective RCT.
Objectives: Little has been known the effectiveness of respiratory muscle training in patients with both stroke and heart failure.
- Trial name
- NCT02614001
- Testing
- Threshold® IMT HS730, RESPIRONICS Inc, Cedar Grove, NJ, USA, post-stroke rehabilitation program
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Myocardial Reperfusion Injury
Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit)
The use of volatile anesthetics in cardiac anesthesia is very common, because of their cardioprotective effects and their ability to ensure a sufficient depth of anesthesia.
- Trial name
- NCT01601795
- Testing
- Sevoflurane, Isoflurane
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Heart Failure, Vitamin D Deficiency
Vitamin D Supplementation in Chronic Stable Heart Failure
In cross-sectional and prospective cohort studies, vitamin D deficiency is associated with increased mortality, cardiovascular events including sudden cardiac death and stroke, diabetes, hypertension and impaired function of the…
- Trial name
- VITD-HI (NCT01292720)
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- Medical University of Graz