Clinical trials: Stable Heart Conditions
Stable Angina
Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina
ORBITA-FIRE is a randomised, double-blinded, placebo controlled experimental study that will identify the fractional flow reserve (FFR) and non-hyperemic pressure ratio (NHPR) thresholds that correlate with symptoms of angina for…
- Trial name
- ORBITA-FIRE (NCT05459051)
- Testing
- Rest-angina physiological assessment, Exercise-angina physiological assessment
- Where
- 6 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Imperial College London
Angina, Stable, Congestive Heart Failure
Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
This feasibility trial will focus on older adults 60+ who are candidates for cardiac or pulmonary rehabilitation and who are vulnerable, mildly or moderately frail.
- Conditions
- Angina, Stable, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05562037
- Testing
- Stepped Care
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- Peter Lindenauer, MD
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Stable Angina, Multivessel Coronary Artery Disease
Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina
ORBITA-MOON is a double-blinded, placebo-controlled experimental study that aims to understand how the different coronary artery stenoses contribute to overall clinical angina in patients with multi-vessel coronary artery…
- Trial name
- ORBITA-MOON (NCT06400290)
- Testing
- Percutaneous coronary intervention (PCI), Symptom assessment during experimentally induced ischaemia
- Where
- 8 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
Coronary Heart Disease, Stable Angina Pectoris
Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation
The objective of this study is a comparative evaluation of Orsiro stent and of Resolute Integrity stent in terms of the extent of neointima formation at 4 months after implantation using optical coherence tomography (OCT).
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- Healing (NCT04465669)
- Testing
- Orsiro stents, Resolute Integrity® stents
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Myocardial Infarction, Percutaneous Transluminal Coronary Angioplasty
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
The aim of this study is to evaluate feasibility, efficacy, and adherence of home-based cardiac rehabilitation with the integration of telemedicine.
- Conditions
- Myocardial Infarction, Percutaneous Transluminal Coronary Angioplasty, Coronary Artery Bypass, Stable Angina
- Trial name
- NCT05972070
- Testing
- ROMTech Portable Connect
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- ROM Technologies, INC
Stable Angina, Unstable Angina, Silent Coronary Ischemia, Coronary Artery Disease
ISAR-DAPT (A Comparative Evaluation of Efficacy and Safety in the 3-Months DAPT Group vs. the 6-Months DAPT Group of Patients Treated With the Coroflex ISAR Stent; A Prospective, Multicenter, Randomized, Open-Label Clinical Trial)
This clinical trial studies patients treated with the Coroflex ISAR Stent for coronary artery disease in order for the objective of verifying the non-inferiority of results that among patients who were administered DAPT for 3…
- Trial name
- NCT02609698
- Testing
- Coroflex ISAR, 3 months DAPT, 6 months DAPT
- Where
- South Korea
- Volunteers
- 906 people
- Sponsor
- Ajou University School of Medicine
Atrial Fibrillation
Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care Unit
Atrial fibrillation (AF) is an abnormal heart rhythm that is common among patients who are admitted to an intensive care unit (ICU) of a hospital.
- Trial name
- AFIB (NCT01461733)
- Testing
- amiodarone
- Volunteers
- 25 people
- Sponsor
- Ottawa Hospital Research Institute
Severe Cardiomyopathy, Angina, Unstable
Hemodynamics During the Soccer Championship 2012
The purpose of this study is to determine in soccer fans whether and to which extend positive or negative emotions during the European soccer Championship affects Central Hemodynamics, Arterial Stiffness, Heartrate and…
- Conditions
- Severe Cardiomyopathy, Angina, Unstable, Myocardial Infarction, Angina, Stable
- Trial name
- NCT01617863
- Where
- 4 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Ekg Change Ischemia Lateral
Diagnostic Value of Electrocardiographic St-t Wave Changes in Patients With Chronic Stable Angina
The electrocardiogram (ECG) is a simple and non-invasive bedside diagnostic tool with a well-established role in the diagnosis of (CAD).
- Trial name
- ECG (NCT02027506)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Ventricular Tachycardia
Inducibility and Stability of Ventricular Tachycardia Inpatients Undergoing VT Ablation Under General Anesthesia
This research study is being done to see whether general anesthesia (GA) affects our ability to start ventricular tachycardia (VT) during an VT ablation procedure.
- Trial name
- NCT02419547
- Testing
- Versed, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Stable Angina
Safety and Efficacy Study of Endothelial Progenitor Cell Capture Stent With 1 Months Dual Antiplatelet Therapy
Thanks to rapid reendothelialization derived from the pro-healing property of the EPC capture stent, 1-month dual antiplatelet therapy (DAPT) is recommended after EPC capture stent implantation.
- Trial name
- INNOVATION (NCT01394848)
- Testing
- Endothelial cell capture stent with 1 month clopidogrel, Everolimus eluting stent with 12 month clopidogrel, Atorvastatin 20mg loading
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Yonsei University
Cardiac Output, Low, High Blood Pressure
Assessment of Volumetric Hemodynamic Parameters and Nutritional Status in Stable Renal Transplant Recipients
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Trial name
- NCT02852941
- Testing
- CardioScreen 1000, Tanita 418- Bioelectrical impedance analysis
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes
Appropriateness of Coronary Angioplasty in PAtients With isCHEmic Heart Disease
An observational, retrospective, multicenter, blinded adjudication study to evaluate the clinical appropriateness of Percutaneous Coronary Intervention (PCI) indication and execution in patients with stable Coronary Artery…
- Conditions
- Non ST Elevation Acute Coronary Syndromes, Stable Coronary Syndromes, NSTEMI, Unstable Angina
- Trial name
- APACHE (NCT02748603)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Italian Society of Invasive Cardiology
Angina Pectoris, Diabetes Mellitus, Type 2
Study Protocol for Rosiglitazone Versus Gliclazide in Diabetics With Angina
The principle objective of the trial is to compare rosiglitazone to gliclazide in patients with type 2 diabetes mellitus and chronic stable angina to see how the subjects' angina status changes.
- Trial name
- NCT00225342
- Testing
- Rosiglitazone, Gliclazide (Comparison drug)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Stable Angina Pectoris, Unstable Angina Pectoris
Non-invasive Diagnosis of Coronary Artery Stenoses by Doppler Echocardiography
Non-invasive evaluation of patients with stable angina and unstable coronary syndromes with transthoracic Doppler echocardiography to evaluate presence of significant coronary stenoses.
- Conditions
- Stable Angina Pectoris, Unstable Angina Pectoris, Acute Myocardial Infarction
- Trial name
- NCT00281346
- Testing
- Doppler echocardiography
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Stable Angina, Coronary Artery Disease
Safety of Amiodarone and Ranolazine Together in Patients With Angina
Ranolazine is an effective and remarkably safe agent for the treatment of patients with chronic stable angina, but its inhibition of voltage gated potassium channels and electrocardiogram (EKG) corrected QT (QTc) prolongation…
- Conditions
- Chronic Stable Angina, Coronary Artery Disease, Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- SARA (NCT01558830)
- Testing
- ranolazine
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cardiovascular Consultants of Nevada
Stable Angina
Boston Scientific COMET Wire Validation Study
Summary of Study Aims To assess, in a randomised fashion: 1. performance of Boston Scientific Pressure Wire versus St Jude Pressure Wire 2. performance of Boston Scientific Pressure Wire versus Boston Scientific Pressure Wire 3.
- Trial name
- COMET (NCT02578381)
- Testing
- Boston Scientific Pressure Wire, Validation of Boston Scientific pressure wire
- Where
- 2 sites in United Kingdom
- Volunteers
- 106 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cervical Intraepithelial Neoplasia
Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization
Cervical conization is done for pre-cancer disease. The procedure is performed with local anesthesia and general anesthesia. Local anesthesia is given by paracervical block, and several different local anesthetics is being used…
- Trial name
- HSBAPCB (NCT02368054)
- Testing
- Bupivacaine, Adrenaline
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Helse Fonna
Chronic Stable Angina
Allopurinol in Acute Coronary Syndrome
Allopurinol is a drug commonly used to treat gout. However recent studies have shown it has the potential to help improve oxygen supply to heart muscle.
- Trial name
- ALLACS (NCT01457820)
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Stephen McSwiggan