Clinical trials: Stable Heart Conditions
Heart Failure With Reduced Ejection Fraction
Improving the Criteria for Selecting Patients for Primary Prevention of Sudden Cardiac Death by Arrhythmic Risk Stratification
A number of large randomized studies have demonstrated the importance of left ventricle ejection fraction (LV EF) for ventrucular tachyarhrythmia's (VT) prediction.
- Trial name
- PERFECT (NCT05539898)
- Testing
- ICD implantation
- Where
- Russia
- Volunteers
- 450 people
- Sponsor
- Astrakhan Federal Centre For Cardiac Surgery
Angina, Stable, Coronary Vasospasm
CORonary MICrovascular Angina (CorMicA)
Angina is form of chest pain that is due to a lack of blood to the heart muscle. Angina is commonly triggered by stress and exertion, and is a common health problem worldwide.
- Conditions
- Angina, Stable, Coronary Vasospasm, Coronary Circulation, Coronary Syndrome
- Trial name
- CorMicA (NCT03193294)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 151 people
- Sponsor
- NHS National Waiting Times Centre Board
Acute Coronary Syndrome, Angina Pectoris, Unstable
Incremental Value of Point of Care H-FABP Testing in Primary Care Patients Suspected of Acute Coronary Syndrome
Rationale: Thoracic complaints, possibly due to a cardiac ischemic cause are a diagnostic challenge in general practice. When an underlying ischemic cardiac condition (AMI (acute myocardial infarction), UAP (unstable angina…
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Unstable, Angina Pectoris, Stable, Thoracic Diseases
- Trial name
- RAPIDA (NCT01826994)
- Testing
- heart type fatty acid binding protein testing
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 303 people
- Sponsor
- Maastricht University Medical Center
Coronary Artery Disease, Stable Angina
Functional Assessment of Myocardial Ischemia by Intracoronary Electrocardiogram
In patients with chronic stable coronary artery disease (CAD), percutaneous coronary intervention (PCI) targets hemodynamically significant coronary lesions, i.e., those thought to cause inducible ischemia.
- Conditions
- Coronary Artery Disease, Stable Angina, Coronary Artery Stenosis, Ischemia
- Trial name
- FFRicECG (NCT03985241)
- Testing
- Functional Assessment of Myocardial Ischemia by icECG
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London
Angina, Stable, Angina Pectoris, Variant
Coronary Microvascular Function and CT Coronary Angiography (CorCTCA)
Angina in patients without obstructive coronary artery disease (CAD) is a clinical conundrum and patient management is heterogeneous. Hypothesis: Abnormal coronary function is common and clinically relevant in this population.
- Conditions
- Angina, Stable, Angina Pectoris, Variant, Microvascular Angina
- Trial name
- CorCTCA (NCT03477890)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- NHS National Waiting Times Centre Board
Angina Pectoris, Coronary Artery Disease
Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events
Compared with standardized western medical drug therapy, this study is mainly about whether the combination of standardized western medical drug therapy and Chinese medical continued treatment, can further decrease the rate of…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Coronary Disease, Heart Disease
- Trial name
- NCT01715376
- Where
- China
- Volunteers
- 1,042 people, healthy volunteers welcome
- Sponsor
- Changchun University of Chinese Medicine
Atrial Fibrillation, Heart Valve Diseases
Prolongation of the Interval Between Monitoring of Warfarin in Stable Patients
Patients with mechanical heart valve prosthesis or with irregular beat (atrial fibrillation) have a high risk of blood clot formation. Such clots can result in a stroke.
- Conditions
- Atrial Fibrillation, Heart Valve Diseases, Venous Thrombosis
- Trial name
- NCT00356759
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Hamilton Health Sciences Corporation
Cardiovascular Diseases, Myocardial Infarction
Exercise as a Life-long Medicine in Patients With Coronary Artery Disease
Exercise training is a core component in cardiac rehabilitation. Exercise adherence is, however, low after rehabilitation and the transition from supervised to unsupervised exercise is problematic for many patients with coronary…
- Conditions
- Cardiovascular Diseases, Myocardial Infarction, Angina (Stable)
- Trial name
- NCT02228603
- Testing
- high-intensity exercise training, web-based follow-up program, usual care
- Where
- 2 sites in Norway
- Volunteers
- 161 people
- Sponsor
- Norwegian University of Science and Technology
Stable Angina Pectoris, Atherosclerosis
Effect of Molsidomine on the Endothelial (Internal Layer of Blood Vessels) Dysfunction in Patients With Angina Pectoris
Molsidomine used as an add-on treatment on standard care therapy should be superior to placebo used also as an add-on treatment on standard care therapy on improving the endothelial function (endothelium score measured by…
- Trial name
- MEDCOR (NCT01363661)
- Testing
- Coruno
- Where
- Belgium
- Volunteers
- 165 people
- Sponsor
- Therabel Pharma SA/NV
Coronary Artery Disease, Stable Angina
Comparison of Drug Eluting Balloon and Drug Eluting Stent
The purpose of this study is to evaluate the safety and efficacy of Drug-Eluting Balloon first and then bare metal stent compared with drug-eluting stent for treatment of de novo lesions (DEB first).
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina, NSTEMI
- Trial name
- DEBfirst (NCT01539603)
- Testing
- Drug eluting balloon + Bare metal stent, drug eluting stent (Zotarolimus-eluting stent)
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul National University Bundang Hospital
Hip Fractures, Hypotension on Induction
Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.
Background During anaesthesia for repair of a broken hip, many patients experience low blood pressure. There have been many studies showing that patients who experience low blood pressure during anaesthesia are at increased risk…
- Conditions
- Hip Fractures, Hypotension on Induction, Intraoperative Hypotension, Acute Kidney Injury
- Trial name
- iSTABILISE (NCT04051073)
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Ventricular Tachycardia, Coronary Artery Disease
Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy
The main objective of this study is to compare the time from randomization to the first recurrence of any ventricular tachycardia (VT) in patients undergoing VT ablation (for stable VTs) and substrate ablation (for unstable VTs)…
- Conditions
- Ventricular Tachycardia, Coronary Artery Disease, Left Ventricular Dysfunction
- Trial name
- VTACH (NCT00919373)
- Testing
- Substrate modification, VT ablation, ICD Implantation
- Where
- 16 sites in Czechia, Denmark and 2 more
- Volunteers
- 110 people
- Sponsor
- Abbott Medical Devices
Abdominal Aortic Aneurysm, Acute Myocardial Infarction
Body Mass Index and Initial Presentations of Cardiovascular Diseases
The association between obesity and cardiovascular disease (CVD) has mostly been studied using broad endpoints or have focused on cause-specific mortality.
- Conditions
- Abdominal Aortic Aneurysm, Acute Myocardial Infarction, Stroke, Heart Failure
- Trial name
- CALIBER (NCT01704300)
- Where
- United Kingdom
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Coronary Artery Disease, Atherosclerotic Plaque
STabilization of Atheroma by Lipid-reducing Effect of Drug-Coated Balloon (STABLE-DCB)
This study aims to investigate whether DCB angioplasty, compared to statin-based medical treatment alone, will lead to more reduction in plaque lipid burden as assessed by near infrared spectroscopy (NIRS) at 6-9 months following…
- Conditions
- Coronary Artery Disease, Atherosclerotic Plaque, De Novo Stenosis
- Trial name
- STABLE-DCB (NCT05438121)
- Testing
- SeQuent Please Neo
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Korea University Ansan Hospital
Stable Angina Pectoris, Acute Coronary Syndrome
Randomized "All-comer" Evaluation of a Permanent Polymer Resolute Integrity Stent Versus a Polymer Free Cre8 Stent
The study objective is to assess the safety and efficacy of the Permanent Polymer Zotarolimus-Eluting Stent Resolute Integrity™ to the Polymer Free Amphilimus-Eluting Stent Cre8™ compared in an all-comer patient population.
- Trial name
- NCT02328898
- Testing
- Cre8 Stent, Resolute Integrity stent
- Where
- 3 sites in Luxembourg, Netherlands
- Volunteers
- 1,532 people
- Sponsor
- UMC Utrecht
Dyspnea, Coronary Artery Disease
Dyspnea in Stable Patients With Coronary Artery Disease.
Single-centre prospective study to characterize causes of dyspnea in stable patients with coronary artery disease and evaluate the possibility to determine the cause of dyspnea before in-depth examination.
- Trial name
- NCT04408612
- Testing
- Scales for assessment of symptoms
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Research Center for Preventive Medicine
Supraventricular Tachycardia (SVT), Atrioventricular Nodal Re Entrant Tachycardia
Adenosine vs. Diltiazem
In this Emergency Department (ED)-based study, the investigators evaluated a standardized modified Valsalva maneuver (MVM) as first-line therapy and compared intravenous (IV) adenosine with IV diltiazem among patients with…
- Trial name
- AVNRTstdy (NCT07456423)
- Testing
- Adenosine intravenous, Diltiazem intravenous
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Haseki Training and Research Hospital
Stable Chronic Angina, Ischemic Heart Disease
Effect of Remote Intervention in Patients With SCAD
The study was a multicenter, two-arm, parallel, open-label, prospective clinical trial that evaluated a remote intervention with 1 year of follow-up.
- Conditions
- Stable Chronic Angina, Ischemic Heart Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- NCT04795492
- Testing
- remote intervention, Routine outpatient follow-up
- Where
- China
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital