Clinical trials: Stage I Prostate Cancer
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
EXERCISING TOGETHER for Couples Coping With Cancer
The Exercising Together trial is a single-blind, parallel group, randomized controlled trial comparing 3 arms: Arm 1 (experimental): Exercising Together where couples perform partnered exercise in a supervised, group setting…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma
- Trial name
- NCT03630354
- Testing
- Exercise Intervention (supervised), Exercise Intervention (unsupervised), Informational Intervention
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
DNA Changes in Patients With Prostate Cancer
RATIONALE: Collecting and storing samples of blood from patients and their brothers with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899184
- Testing
- polymorphism analysis, laboratory biomarker analysis
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Prostatic Neoplasms
Irreversible Electroporation(IRE) For Unresectable Prostatic Neoplasms
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Prostatic Neoplasms.
- Trial name
- IRE (NCT02430649)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Prostate Cancer
Study of 2 Different Doses of Revlimid in Biochemically Relapse Prostate Cancer
The primary objectives of the study are: To evaluate feasibility, safety and tolerance of 6 months administration of Revlimid at 5mg/day and 25mg/day, given orally in subjects with prostate cancer with evidence of biochemical…
- Trial name
- NCT00348595
- Testing
- Revlimid
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
This clinical trial evaluates whether positron emission tomography-magnetic resonance imaging (PET-MRI) using the radioactive drug radiohybrid prostate-specific membrane antigen (rhPSMA)-7.3 may help in detecting higher grade or…
- Conditions
- Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8
- Trial name
- NCT05852041
- Testing
- Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prostate Cancer
99mTc-MIP-1404 for Imaging Prostate Cancer: Phase I Clinical Study to Assess the Image Quality of a Simplified Kit Formulation Compared to a Multi-step Preparation of 99mTc-MIP-1404
This trial is a single-blind, cross-over design. Up to three patients with confirmed metastatic prostate adenocarcinoma and up to three healthy volunteers will receive two doses of 20.0 (± 3) mCi of intravenously administered…
- Trial name
- NCT01654874
- Testing
- 99mTc-MIP-1404
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Molecular Insight Pharmaceuticals, Inc.
Prostatic Neoplasms
PK, PD, Tolerability and Safety of MDPK67b in Healthy Volunteers
This is a Phase I, single centre, prospective, randomized, alternating panels, ascending doses with interspersed placebo, double-blind, crossover trial.
- Trial name
- NCT04839120
- Testing
- MDPK67b
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Med Discovery SA
Adverse Reaction to Diagnostic Agents and Kits Nos
Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI
Cell-based therapies in the form of stem cell-based or immune cell-based therapies are becoming important treatment options that are either approved for clinical use or are showing promise in clinical trials.
- Trial name
- TRACK (NCT02921373)
- Testing
- 19F Cell Sense-labeled PBMC, MRI
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gregory A. Dekaban
Cancer Survivor, Partner
Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners
This trial studies the day-to-day stress, social support, and health lifestyle behaviors (such as physical activity and nutrition) in African American patients with stage 0-III prostate cancer survivors and their partners.
- Conditions
- Cancer Survivor, Partner, Spouse, Stage I Prostate Cancer AJCC v8
- Trial name
- NCT04189770
- Testing
- Accelerometer, Ecological Momentary Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
No Evidence of Disease, Prostate Carcinoma
Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants
This randomized phase I trial studies the side effects and the best dose of Se-methyl-seleno-L-cysteine or selenomethionine in preventing prostate cancer in healthy participants.
- Trial name
- NCT01497431
- Testing
- Selenium, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 3 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy Subjects, Castration Resistant Prostate Cancer (CRPC)
A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects
A study to evaluate the bioavailability (BA) of a single oral dose of MDV3100 (enzalutamide) formulated as a solid spray dried tablet compared to oral liquid-filled capsules, and the safety and tolerability of oral formulations.
- Conditions
- Healthy Subjects, Castration Resistant Prostate Cancer (CRPC), Relative Bioavailability, MDV3100
- Trial name
- NCT01911741
- Testing
- MDV3100
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Healthy Male Subjects, Suspected Prostate Cancer
A Study of PET/CT Imaging Using INR101 Injection in Healthy Male Subjects and Patients With Suspected Prostate Cancer
Phase I/II study in the management of Healthy Male Subjects and patients with suspected prostate cancer.
- Trial name
- NCT06472531
- Testing
- INR101
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Yunhe Pharmaceutical (Tianjin) Co., Ltd
Prostate Cancer, Prostate Cancer Stage I
Randomized Trial of HIFU vs. Cryo for Prostate Cancer
HIFU has been FDA approved and is widely utilized across the United States and Europe for the treatment of prostate cancer. Despite this, HIFU has not been offered within SCPMG until now due to growing patient demand.
- Conditions
- Prostate Cancer, Prostate Cancer Stage I, Prostate Cancer Stage II, High Intensity Focused Ultrasound
- Trial name
- KPFT (NCT06929065)
- Testing
- HIFU vs Cryoablation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Prostate Cancer
Biomarker 11-dh-TXB2 in Blood and Urine Samples From Patients With Prostate Cancer and Healthy Volunteers
RATIONALE: Studying samples of blood and urine from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00984919
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, mass spectrometry
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer
The Efficacy and Safety of Composite Steep-pulse Treatment Apparatus Used in Prostate Cancer Focal Therapy
This trial is studying the effects and safety in treating patients with local prostate cancer with a new IRE device called Composite Steep-pulse Treatment Apparatus.
- Trial name
- NCT03315585
- Testing
- steep pulse device
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Second Military Medical University
Prostatic Intraepithelial Neoplasia
A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia
The purpose of this study is to determine whether dietary lycopene supplementation lowers serum prostate specific antigen(PSA) in men with high grade intraepithelial neoplasia (HGPIN).
- Trial name
- NCT00178113
- Testing
- - Lyc-O-Mato (dietary supplement, 30 mg lycopene/day), - Certagen (multivitamins with minerals)
- Where
- Trinidad and Tobago
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy, no Evidence of Disease, Prostate Cancer
Lycopene in Healthy Male Participants
This randomized phase I trial is studying the side effects and best dose of lycopene in healthy male participants. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00450957
- Testing
- lycopene, pharmacological study
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Lycopene in Preventing Prostate Cancer in Healthy Participants
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development or recurrence of cancer. The dietary supplement lycopene may prevent the development of prostate cancer.
- Trial name
- NCT00093561
- Testing
- lycopene
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Prostate Cancer
Study of a Polymorphism in Patients With Prostate Cancer
RATIONALE: Studying samples of blood from patients with cancer and from healthy participants in the laboratory may help doctors learn more about changes that may occur in DNA.
- Trial name
- NCT00900185
- Testing
- mutation analysis, polymerase chain reaction, polymorphism analysis
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
- Trial name
- NCT00503646
- Testing
- communication intervention, counseling intervention, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center