Clinical trials: Staining
Contact Lens Disinfecting Solutions
Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function
The purpose of this study is to measure the relative "barrier" function of the top layer of the cornea (called the epithelium), or the degree to which the cornea can prevent the penetration of the colored dye sodium fluorescein…
- Trial name
- NCT00560898
- Testing
- ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Staining
Clinical Study to Assess the Efficacy of Professional Tooth Whitening Maintenance System
Clinical study to assess the efficacy of professional tooth whitening maintenance system of a Colgate toothpaste containing 5% Hydrogen Peroxide with a stain-fighter mouthwash as compared to only the stainfighter mouthwash and a…
- Trial name
- NCT06613347
- Testing
- whitening maintenance, whitening maintenance MW, negative control
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bacterial Vaginosis
PNA FISH, PCR and Gram Staining for Detection of Bacterial Vaginosis - a Comparative Clinical Study in a Danish IVF Setting
The primary aim of the present study is to investigate the vaginal microbiota of infertile women with two novel molecular based diagnostic tests for Bacterial Vaginosis, a PNA FISH and a PCR method supported with conventional…
- Trial name
- NCT02042352
- Testing
- pH glove
- Where
- Denmark
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Discoloration, Tooth
Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth
Although black staining is considered a drawback that is clinically observed following SDF application and is the main primary barrier for its use clinically .
- Trial name
- NCT04816487
- Testing
- Potassium Iodide or Glutathione
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Port-Wine Stain
Measurement Skin Temperature During Pulsed Laser Exposure
Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must…
- Trial name
- NCT00540917
- Testing
- cooling spray during laser treatment
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Corneal Staining
A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand
This study is a clinical comparison of the biocompatibility of several multipurpose solutions, Renu Fresh, Optifree Replenish, and ClearCare, and saline as a control solution among adapted hydrogel contact lens wearers wearing…
- Trial name
- NCT01335750
- Testing
- Multipurpose Solution #1, Multipurpose Solution #2, Mutlipurpose Solution #3
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Black stains (BS) are type of extrinsic discoloration of the tooth. It's characterized as dark lines or an incomplete coalescence of dark dots found mostly on cervical third of the crown.
- Trial name
- NCT03563469
- Testing
- Salivary bacterial and pH level
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cairo University
Black Staining
Comparison of Erythritol Air-Polishing and Conventional Polishing Following Ultrasonic Scaling on the Relapse of Chromogenic Tooth Staining in Children
The goal of this randomized clinical trial is to compare the effect of erythritol air-polishing and conventional polishing following ultrasonic scaling on the relapse of chromogenic tooth staining in children aged 4-13 years…
- Trial name
- NCT07730658
- Testing
- Guided Biofilm Therapy with erythritol, Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Contact Lens Solution Toxicity
The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility
The purpose of this study is to more objectively evaluate potential lens-material/care solution bio-incompatibilities. We will do this by measuring corneal staining and the amount of fluorescein dye diffusion into the eye.
- Trial name
- NCT00829751
- Testing
- PureVision lenses soaked in ReNu Multiplus, PureVision lenses soaked in OptiFree RePlenish
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Primary Teeth, Dental Caries
Assessment of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique
The purpose of this study is to evaluate and compare the clinical performance of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique
- Conditions
- Primary Teeth, Dental Caries, Dentin, Carious
- Trial name
- NCT03433157
- Testing
- Hall technique, Traditional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tooth Discoloration
Efficacy of Manual Toothbrushes in Removing Tooth Stains
Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.
- Trial name
- NCT06486974
- Testing
- NaF, Na MFP
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Hygiene
Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
The aim of this study is to investigate the stain removal efficacy of 2 experimental anti-dentin hypersensitivity (DH) dentifrices with four and eight weeks twice daily use.
- Trial name
- NCT05459558
- Testing
- Experimental Dentifrice 1, Experimental Dentifrice 2, Reference Dentifrice
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- HALEON
Vaginal Infection
Research on Vaginal Microbiota Evaluation Unified Standards Based on Gram Staining
The goal of this observational study is to explore a standardized sample process for improving the accuracy of vaginal microbiota evaluation and to explore a more complete and comprehensive method for vaginal microbiota…
- Trial name
- VENUS (NCT05997160)
- Volunteers
- 5,590 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Mineral Trioxide Aggregate
Clinical and Radio-graphic Evaluation of Non-staining Bio-active Bio-ceramic (Neo MTA 2) in Revascularization
The study will compare the clinical and radio-graphic performance of newly introduced non-staining bio-active bio-ceramic (Neo MTA 2) versus White MTA used as coronal plug material in revascularization of non-vital immature…
- Trial name
- NCT06637761
- Testing
- NeoMTA2, WMTA
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Corneal Injury, Exposure Keratopathy
Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection
During general anesthesia, the eye's natural protective reflexes are suppressed, which can lead to corneal drying and injury. To prevent this, anesthesiologists routinely tape the eyelids closed.
- Conditions
- Corneal Injury, Exposure Keratopathy, Perioperative Complications
- Trial name
- NCT07562594
- Testing
- Hypoallergenic Eyelid Taping, Hypoallergenic Eyelid Taping With Lubricant Eye Drops
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Evaluation of Corneal Stability Post-applanation
Icare Tonometry Effects on Keratometry Readings, Topography Readings, and Corneal Staining
To demonstrate that the Icare tonometer does not alter Keratometry readings, topography, or corneal staining. This would therefore allow intraocular pressure (IOP) testing to be done at any time during an exam, without affecting…
- Trial name
- NCT03275142
- Testing
- Icare tonometer
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Comprehensive EyeCare of Central Ohio
Irritable Bowel Syndrome, Digestive System Diseases
Abnormal Expression Proteins, Mitochondrial DNA and miRNA of Irritable Bowel Syndrome
In the investigators study, the investigators will focus on the screening of the related proteins and miRNA to IBS in order to reveal the possible clues or molecular mechanism for this disorder.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases
- Trial name
- IBS (NCT01028898)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital