Clinical trials: Standardization
Pregnancy
Impact of Standardization on Outcomes Following Cervical Ripening
The primary purpose of this study is to determine if vaginal delivery rate is impacted by the use of standardized methods of cervical ripening. Additional outcomes will be evaluated including maternal and fetal outcomes of labor.
- Trial name
- NCT07576881
- Testing
- Cervical Ripening with a double balloon catheter only, Cervical ripening with a double balloon catheter plus misoprostol, Usual-care control group
- Where
- United States
- Volunteers
- 1,158 people, healthy volunteers welcome
- Sponsor
- Indiana University
Allergic Rhinitis
Moxibustion Reduces Symptoms and Improves Quality of Life in Patients With Allergic Rhinitis
The objective of this randomized controlled clinical trial is to compare the therapeutic effect of moxibustion on allergic rhinitis.
- Trial name
- NCT06173882
- Testing
- Ordinary moxibustion volume group, First group of heavy moxibustion, Second groups of heavy moxibustion
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Overactive Bladder, Non Obstructive Urinary Retention
Standardization of Lead Placement for Sacral Neuromodulation Part 2
Prospective observational study. A substantial number of patients do not respond favourably to sacral neurostimulation (SNS) although clinically, they appear to have the same lower urinary tract (LUT) dysfunction characteristics…
- Trial name
- NCT03199443
- Testing
- EMG pelvic floor
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universiteit Antwerpen
Allergy to Grass Pollen
Biological Standardization of Lolium Perenne Allergen Extract
The objective of this study is to determine the biologic activity of a Lolium perenne allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Trial name
- NCT01394289
- Testing
- Lolium allergen extract
- Where
- 2 sites in Spain
- Volunteers
- 31 people
- Sponsor
- Laboratorios Leti, S.L.
Brain Tumors
SIMPLIFication of Care Pathways for Patients With Rare Brain Tumors Through Artificial Intelligence
This study focuses on rare brain tumors, which are heterogeneous entities with different morphological, biological, and clinical characteristics.
- Trial name
- SIMPLIF-AI (NCT06878469)
- Testing
- RehaCom
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Workflow, Costs
Microcomplications in Lap. Cholecystectomy: Reducing Intraoperative Interruptions by High Resolution Standardization
Objective: Investigators aimed to evaluate the impact of a high resolution standardized laparoscopic (HRSL) cholecystectomy protocol on operative time and intraoperative interruptions in a teaching hospital.
- Conditions
- Workflow, Costs, Laparoscopy, Cholecystectomy
- Trial name
- NCT03329859
- Testing
- High resolution standardized laparoscopic cholecystectomy
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
Stress Urinary Incontinence
Standardization of Cough Stress Test
This is a multicenter, prospective, randomized comparative study in which patients are randomized to one of four different bladder volumes and a Cough Stress Test (CST) is performed in both the standing and sitting positions.
- Trial name
- NCT02742584
- Testing
- Cough Stress Test
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Interventional Neuroradiology
Optimizing Reduced-Flow, Low-Volume Contrast Protocols for Cerebral Angiography in Unruptured Aneurysms
Over the past two decades, interventional neuroradiology (INR) has seen significant advances in terms of safety and radiation protection.
- Trial name
- OPIAC (NCT07302646)
- Testing
- Standard (Reference), Reduced volume - standard flow rate, Standard volume - Reduced flow rate
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Strasbourg, France
Infertility (IVF Patients), Infertility
Standardization of Variable Conditions of Embryo Transfer Into the Uterine Cavity in the Procedure of Medically Assisted Procreation in Humans
The EFECT study is a clinical trial designed to determine whether improving the consistency of embryo transfer procedures can increase pregnancy success in patients undergoing frozen embryo transfer (cryoET).
- Conditions
- Infertility (IVF Patients), Infertility, ART
- Trial name
- EFECT (NCT07396181)
- Testing
- Embryocase, Embryopass, Embryocase+Embryopass
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Przychodnia Lekarska nOvum Katarzyna Kozioł, Piotr Lewandowski sp.k.
Liver Steatosis
STANDARDIZATION OF THE PROTOCOL FOR ATTENUATION COEFFICIENT MEASUREMENT
The assessment of liver fat content is important in patients suspected of or diagnosed with chronic liver disease. Non-alcoholic fatty liver disease (NAFLD) is defined by the presence of hepatic fat content ≥5% of hepatocytes.
- Trial name
- NCT07616843
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Prostate Cancer
Studying Repeated DCE-MRI and DWI in Patients Diagnosed With Prostate Cancer
RATIONALE: Diagnostic procedures, such as dynamic contrast-enhanced magnetic resonance imaging or DCE-MRI and diffusion-weighted imaging or DWI, may provide images of prostate cancer or any cancer that remains after biopsy.
- Trial name
- A6701QIBA (NCT01562223)
- Testing
- motexafin gadolinium
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- American College of Radiology Imaging Network
To Establish a Standardized Background Parenchimal Enhancement Classification System
From Variability to Standardization: The Impact of Breast Density on Background Parenchymal Enhancement in Contrast-Enhanced Mammography and the Need for a Structured Reporting System
This retrospective study includes 213 patients who underwent CEM, mammography (MG), and ultrasound (US) between May 2022 and June 2023 at the P.O. 'A. Perrino' Hospital, Brindisi.
- Trial name
- NCT06838117
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- Graziella di Grezia
Ventilator Induced Diaphragm Dysfunction, Respiratory Muscle Weakness
Standardization of IMT Dosage (UTIT) in Mechanical Ventilation.
Respiratory muscle weakness prolongs mechanical ventilation (MV) and delays weaning. Currently, there is no standardized dosage for Inspiratory Muscle Training (IMT) in the ICU.
- Conditions
- Ventilator Induced Diaphragm Dysfunction, Respiratory Muscle Weakness, Mechanical Ventilation Weaning
- Trial name
- UTIT-IMT (NCT07761468)
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital H+ Queretaro
NIRS, Tissue Oxygenation
CHECK-NIRS2D-Study
The study investigates how external, physiological, and behavioral factors influence the measurement of regional tissue oxygenation using two-dimensional near-infrared spectroscopy (NIRS) imaging in healthy volunteers.
- Conditions
- NIRS, Tissue Oxygenation, Microvascular Perfusion, Vascular Occlusion Test
- Trial name
- NCT07854431
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Digital Photography, Standardization
Effect of Using Image Standardization Device for Dental Photography Standerdizatuon in Comparison to Individualized Photography In Vivo Study
This randomized clinical trial aimed to evaluate the effect of Image Standardization Device (ISD) on standardization of clinical images from the same entry point (patient right 45o).
- Conditions
- Digital Photography, Standardization, ISD
- Trial name
- NCT04991363
- Testing
- Bleaching
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Gastric Bypass
Study to Evaluate the Pharmacokinetics of Vitamin D (Cholecalciferol) in Patients Undergoing Obesity Surgery in a Deficit Situation and After Standardization
Set the pattern of vitamin D supplementation in obese patients undergoing bariatric surgery in deficit of vitamin D. Patients receive a single oral dose of vitamin D, during the 28 days will be done a kinetic curve.
- Conditions
- Obesity, Gastric Bypass, Gastrectomy
- Trial name
- PK-VIT-D (NCT01637155)
- Testing
- Cholecalciferol
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Hospital Clinic of Barcelona
Allergy to Alternaria Fungus
To Determine the Minimum Amount of Alternaria Alternata Allergen Extract Producing a Positive Skin Reaction.
The objetive of this study is to determine the minimum amount of Alternaria alternata allergen extract producing in a positive skin reaction.
- Trial name
- NCT01984528
- Testing
- four differente concentrations of Alternaria alternata allergen extract, positive control and negative control
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Laboratorios Leti, S.L.
Dementia
EEG (Electroencephalogram) Platform Standardization in Healthy Male Subjects (3134-010)
The objective of this study is to test the experimental reproducibility and within-subject variability of qEEG (quantitative electroencephalogram) using two probe compounds: MK3134 and lorazepam.
- Trial name
- NCT01110616
- Testing
- MK3134, Comparator: Lorazepam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Adenocarcinoma of Ovary, Adenocarcinoma, Tubular
Establishment and Standardization of a Platform for In-depth Tumour Profiling (TUPRO) in Patients With Advanced and Metastatic High-Grade Adenocarcinoma of Ovarian, Tubal or Peritoneal Origin (TUPRO-Gyn)
The aim of this prospective, multi-centre, exploratory research project is the establishment of a platform for in-depth tumour profiling in patients with advanced and metastatic High-Grade Adenocarcinoma (HGAC) of ovarian, tubal…
- Conditions
- Adenocarcinoma of Ovary, Adenocarcinoma, Tubular, Peritoneal Cancer
- Trial name
- NCT06599749
- Where
- 3 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypertension, Pre-eclampsia
Clinical Validation of the Blood Pressure Measuring Device Withings BPM Pro 2 in Pregnancy and Pre-Eclampsia
The aim of the study is to assess the accuracy of the automatic oscillometric BP measuring device at the brachial level, the WITHINGS BPM Pro 2, in pregnancy and pre-eclampsia
- Trial name
- WIHYP-PW (NCT07595016)
- Testing
- Blood pressure measurement
- Where
- Armenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Withings