Clinical trials: Statin Prescribing
HIV, Cardiovascular Diseases
INcreasing Statin Prescribing in HIV Behavioral Economics REsearch
Cardiovascular disease is a major cause of morbidity and mortality among people living with HIV. Recent studies have demonstrated that patients with HIV experience a 50-100% increased risk of myocardial infarction and stroke…
- Trial name
- INSPIRE (NCT03687060)
- Testing
- Knowledge assessment, Education Intervention, Provider Feedback
- Where
- 8 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Cholesterol, Elevated, Clinical Decision Support
Statin Reminders for Improving Prescribing in Primary Care
Statins reduce cardiovascular events and mortality, but only 30% of eligible primary care patients nationally are on statins. Clinical decision support (CDS) interventions in the electronic health record (EHR) can deliver…
- Conditions
- Cholesterol, Elevated, Clinical Decision Support, Education
- Trial name
- NCT06456658
- Testing
- Interruptive Reminder, Non-interruptive Reminder, No Reminder
- Where
- United States
- Volunteers
- 3,332 people
- Sponsor
- Vanderbilt University Medical Center
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
Hypercholesterolemia
Pharmacogenomic Informed Statin Prescribing
Statins are the most cost-effective medications to lower cholesterol and cardiovascular disease (CVD) risk. However, many patients at high-risk for CVD do not accept or adhere to statins.
- Trial name
- NCT06568601
- Testing
- Pharmacogenetic and polygenic risk testing, Active control
- Where
- 2 sites in United States
- Volunteers
- 410 people
- Sponsor
- VA Office of Research and Development
Heart Failure
Polypharmacy in the Heart Failure Patient: Are All Prescribed Drug Classes Required? Statin Withdrawal Study
Heart failure (cardiomyopathy) is a chronic condition in which the heart fails to function as a pump to move blood around the body.
- Trial name
- NCT01554592
- Testing
- Withdrawal of statin therapy, Statin therapy
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- The Alfred
Deprescribing, Statin Prescribing
Testing the Impact of Pre-visit Priming for Medications
We will use EHR data to identify eligible patients at BWH primary care clinics. Patients will be eligible if they have an upcoming primary care provider (PCP) appointment at an included BWH clinic, are ≥65 years, and are eligible…
- Trial name
- NCT07281131
- Testing
- Pre-visit prompts
- Where
- United States
- Volunteers
- 1,700 people
- Sponsor
- Brigham and Women's Hospital
Hypercholesterolemia
Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)
The purpose of this study is to evaluate the safety and tolerability of the low-density lipoprotein-cholesterol (LDL-C) lowering in an Indonesian population treated with ezetimibe co-administered with a statin in routine daily…
- Trial name
- NCT00705081
- Testing
- ezetimibe, statin
- Volunteers
- 453 people
- Sponsor
- Organon and Co
Hyperlipidemias
Centralized Prescribing for Statins
This pilot study consists of a pair of pragmatic clinical trials that will evaluate two separate methods for optimizing referral of eligible patients to a centralized pharmacy service for statin management: 1) A stepped wedge…
- Trial name
- NCT05537064
- Testing
- Non-visit Based Intervention, Visit-Based Intervention
- Where
- United States
- Volunteers
- 1,950 people
- Sponsor
- University of Pennsylvania
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
Cardiovascular Diseases
Nudges for Statin Prescribing in Primary Care
The objective of the study is to evaluate the effect of nudges to clinicians, patients, or both to initiate statin prescriptions for patients that meet national guidelines.
- Trial name
- NCT04307472
- Testing
- Clinician Nudge, Patient Nudge
- Where
- United States
- Volunteers
- 4,131 people
- Sponsor
- University of Pennsylvania