Clinical trials: Stem Cell
Amyotrophic Lateral Sclerosis
Mesenchymal Stem Cell Injection in Amyotrophic Lateral Sclerosis
Whether the mesenchymal injection on ALS patients is effective or not?
- Trial name
- NCT02116634
- Testing
- mesenchymal stem cell
- Where
- Iran
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alzahra Hospital, Iran
Acute Graft-versus-Host Disease, Hematopoietic Stem Cell Transplantation
Tissue-resident Immune Cell Subsets in aGVHD
This is a prospective study investigating the role of tissue-resident immune cell subsets in the occurrence and progression of graft-versus-host disease following hematopoietic stem cell transplantation.
- Trial name
- NCT06708507
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Healthy Men
Time-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals
Only few data are available on the influence of strenuous exercise on the content of circulating progenitor cells and especially the timeframe of their release.
- Trial name
- NCT00900107
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Non-Small-Cell Lung Carcinoma, Digestive System Neoplasms
Clinical Trial: Effectiveness and Efficiency of Physical Exercise in Cancer Patients
AIM: To evaluate the effectiveness and efficiency of an innovative exercise program (EP) for patients during treatment for gastrointestinal tumors, breast and non small cells lung cancer, in terms of improved quality of life…
- Conditions
- Non-Small-Cell Lung Carcinoma, Digestive System Neoplasms, Breast Neoplasms
- Trial name
- EFICANCER (NCT01786122)
- Testing
- Supervised Physical activity, education program on healthy habits
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Breast Cancer
Breast Stem Cells in Women at Average Risk and Increased Risk for Breast Cancer
Background: Research suggests that breast cancers may arise from a population of stem cells in the normal mammary gland that produce clones of cancer cells.
- Trial name
- NCT00923377
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Increase Success Rate of Tooth Transplantation
Use of CBCT-based Tooth Replica in Tooth Autotransplantation to Improve the Outcome of Tooth Replacement in Children
The aim of this study lies in comparing the outcome of the proposed technique in a large sample size group to the outcome of the conventional tooth autotransplantation method and to provide sufficient evidence for improving the…
- Trial name
- NCT02464202
- Testing
- stereolithography tooth replica
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hematopoietic Transplantation, Bone Marrow Transplantation
Effects of Orange Oil Aromatherapy on the Pain and Anxiety
This randomized controlled experimental study was conducted prospectively with 80 patients with hematological malignancies were treated in the adult bone marrow transplant unit and adult hematology service of a private hospital…
- Trial name
- NCT05391347
- Testing
- Orange oil aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Combination of SVF and PRP for Androgenetic Alopecia
Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia
Androgenetic alopecia (AGA) is a common form of hair loss in both men and women, characterized by progressive patterned loss of hair from the scalp.
- Trial name
- AGA (NCT02865421)
- Testing
- stem cells, platelet rich plasma
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Thrombocytopenia, Isolated, Stem Cell Transplant Complications
AZA Combined With NAC for PIT After HSCT
Prolonged isolated thrombocytopenia (PIT) that is refractory to conventional treatments has remained a critical complication after allogeneic hematopoietic cell transplantation since decades years ago.
- Trial name
- NCT05126004
- Testing
- Azacitidine, N Acetyl L Cysteine
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Soochow University
Graft-versus-host Disease, Poor Graft Function
Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function
The present project aims at investigating the role of MSC for the treatment of patients with Part 1: Steroid-refractory grade II-IV acute GVHD.
- Conditions
- Graft-versus-host Disease, Poor Graft Function, Low Donor T-cell Chimerism
- Trial name
- NCT00603330
- Testing
- Mesenchymal stem cells
- Where
- 12 sites in Belgium, Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liege
GBM, DIPG Brain Tumor
Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma
Primary brain malignant tumor has become the first lethal tumor in children and young adults, and the treatment is limited, and the prognosis of patients is poor.
- Conditions
- GBM, DIPG Brain Tumor, Medulloblastoma
- Trial name
- CSAγδTBMG (NCT06396481)
- Testing
- Vγ9Vδ2 T cell
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Leukemia, Myelocytic, Acute
Infection and Tumour Antigen Cellular Therapy
This study is to test a new therapy for patients with acute myeloid leukaemia who are undergoing blood stem cell transplant. In this study, the investigators will take a small number of your immune cells whose normal function is…
- Trial name
- INTACT-WT1 (NCT02895412)
- Testing
- Donor-derived WT1-CTL and P-CTL
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Cancer Survivor, Diabetes Mellitus
Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant
This pilot clinical trial studies computed tomography (CT) scans and biomarker analysis in diagnosing coronary artery disease (CAD) in patients who have undergone a stem cell transplant but have no symptoms of CAD.
- Conditions
- Cancer Survivor, Diabetes Mellitus, Hypertension
- Trial name
- NCT02077218
- Testing
- computed tomography, cytology specimen collection procedure, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Sickle Cell Anemia
Sickle Cell Disease and Endothelial Progenitor Cells (EPCs)
Sickle Cell Disease (SCD) is the most prevalent genetic disease of haemoglobin.The underlying abnormality in the red blood cell (RBC) of SCD is the presence of abnormal sickle cell hemoglobin (HbS), which, when deoxygenated…
- Trial name
- DREPANOPEC (NCT00783627)
- Testing
- Angiography
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metabolic Syndrome
The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
The aim of the present study is to characterize novel mechanisms whereby HDL may exert potent vasculoprotective effects independent of reverse cholesterol transport, in particular the effect of HDL on the regulation of the…
- Trial name
- NCT00346970
- Testing
- Extended-Release Niacin
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Wound Healing, Burn
Adult Stem Cell Response to Burn Injury
This study is designed to determine the response of adult stems cells, also referred to as mesenchymal stem cells (MSCs), to tissue injury resulting from thermal burns.
- Trial name
- NCT00609661
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Autologous Stem Cell Transplantation
NOX-A12 First-in-human (FIH) Study
This is the first time NOX-A12 will be administered to man. The principal aim of this study is to obtain safety and tolerability data when NOX-A12 is administered by single intravenous (IV) doses to healthy male and female…
- Trial name
- NCT00976378
- Testing
- NOX-A12
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- TME Pharma AG
Rectal Injury
A Study of TH-SC01 in the Treatment of Radiation-induced Rectal Injury
The purpose of this study is to evaluate the efficacy and safety of allogeneic umbilical cord mesenchymal stem cells in the treatment of radiation-induced rectal injury.
- Trial name
- NCT05939778
- Testing
- TH-SC01(Umbilical cord mesenchymal stem cells)
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Skin Burn Degree Second
Stem Cell Therapy to Improve Burn Wound Healing
This study will determine the safety of allogeneic stem cell therapy from healthy donors, for 2nd degree burn wounds of less than 20% Total Body Surface Area (TBSA), at four different dose levels.
- Trial name
- NCT02104713
- Testing
- Allogeneic (MSC's) Application to the Burn Wounds
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- E.Badiavas
Infertility
Derivation of New Human Embryonic Stem Cell Lines Lines for Clinical Use
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body.
- Trial name
- NCT00353197
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization