Clinical trials: Sterility
Uterine Factor Infertility
Uterus Transplantation to Treat Infertility
This research study will use uterus transplantation to treat uterine factor infertility, also known as the inability to bear children due to not having a uterus.
- Trial name
- OPRTUNTI (NCT05646992)
- Testing
- Uterine Allotransplantation, Tacrolimus, Imuran
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Female Infertility
Levels of Anti-Mullerian Hormone (AMH) During Ovarian Stimulation With Gonadotropins
Anti-Mullerian Hormone (AMH) is produced only in small ovarian follicles with quite stable levels during the cycle. There is not yet sufficient data to inform couples undergoing IVF about the effect of ovarian stimulation on the…
- Trial name
- NCT02237781
- Testing
- Gonadotropins
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Athens
Infertility
The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve
The uterine leiomyoma is the most common female benign disease.UPA seems to be most effective for the medical management of fibroids and could be place as preoperative adjunct to surgery but also as medical therapy to avoid…
- Trial name
- UPA_ovAge (NCT02361892)
- Testing
- ulipristal acetate
- Where
- Italy
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Fertility Issues
Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve
The incorporation of ovarian reserve tests in IVF management started after initial publications indicating a potential role for basal FSH in predicting pregnancy outcome after IVF and in counseling patients (1,2).
- Trial name
- NCT05536999
- Testing
- Blood sample taking , like to measure hormonal level like LH, FSH, Perlakan ,in a follicular fluid after the oocyte retrival
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infertility
Use of Antagonist Versus Agonist GnRH in Oocyte Recipient Endometrium Preparation
Oocyte donation is a well established procedure in assisted reproduction treatments (ART). It is demonstrated that the use of hormonal substitution therapy, for the synchronization of the cycles between the recipients and the…
- Trial name
- NCT00633347
- Testing
- Antagonist GnRH Cetrotide, Agonist GnRH Acetate Triptoreline
- Where
- Spain
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Hysteroscopy, Hysteroscopy Technique
UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY. This Study Will Compare the Intrauterine Pathology Detection Rate Between Standard of Care Hydrosonography, and a New Visual Saline Infusion Device Providing Direct Visualization of the Uterus.
This is a prospective, single center, multiple arm cohort study intended to compare the diagnostic accuracy of a Visual Saline Infusion Device (VSI) device, vs standard of care Hydrosonography in reproductive aged women to…
- Conditions
- Hysteroscopy, Hysteroscopy Technique, Fertility Issues, Uterus Abnormal
- Trial name
- NCT06394752
- Testing
- Visual Saline Infusion, Hydrosonography
- Where
- 2 sites in United States, Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Center for Reproductive Health & Gynecology
Infertility
3D Ultrasound Uterine Characteristics of Women Undergoing IVF/ICSI Treatment
The purpose of this trial is to evaluate the morphological characteristics of the uterus with three-dimensional ultrasound (3DUS) at the time of IVF/ICSI treatment and correlate it to clinical outcomes.
- Trial name
- NCT02549235
- Testing
- Ultrasound
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Infertility, Female
The Role of Erzhi Tiangui Formula in Expected POR Women Undergoing IVF-ET
This randomized controlled trial aims to determine whether Erzhi Tiangui Formula can optimize the reproductive outcomes of elderly patients with expected poor ovarian response, and to provide a new approach to traditional Chinese…
- Trial name
- NCT05698550
- Testing
- Erzhi Tiangui Granule
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
MIRAS, Testicular Abnominalies
Could miRNAs be Used as Markers for Distinguishing Undescended Testicles From Retractile Testicles
Background: Undescended testicles (UDTs) are common in male infants. Untreated UDT poses risks such as infertility (IF), testicular cancer (TC), and testicular torsion (TT).
- Conditions
- MIRAS, Testicular Abnominalies, Undescended Testes
- Trial name
- miRNA (NCT07315737)
- Testing
- miRNA
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dr. Mevlüt Keleş
Infertility Unexplained
Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles
The aim of study is to evaluate the results of two different protocols for ovulation induction during IUI cycles. All patients undergo IUI cycles are randomly divided in to two groups.
- Trial name
- NCT05670795
- Testing
- Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility, Female, IVF
Effect of Intrauterine Administration of Autologous PBMC Modulated With IFNt on IVF Outcome
The goal of this clinical trial is to test the effect of modulated specialised immune cells isolated from the patients' own blood when administered to the uterus before embryo transfer on the IVF outcome (implantation, pregnancy…
- Trial name
- NCT05775198
- Testing
- PBMC immunomodulated with IFNt
- Where
- Bulgaria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nadezhda Women's Health Hospital
Infertility, in Vitro Fertilization
Ultrasound Guided Embryo Transfer: Abdominal Versus Transvaginal, a RCT
Ultrasound (US) guided embryo transfer (ET) appears to improve pregnancy outcomes in IVF-ET. Most reports are done using a transabdominal (TAS) approach, in contrast to a transvaginal ultrasound (TVS) which does not require a…
- Trial name
- NCT00682071
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Infertility, Female
Cabergoline Before or After Oocyte Collection for Follicular Resolution
Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.
- Trial name
- NCT04096027
- Testing
- Cabergoline Pill
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Infertility, Male
Microbiome Influence on Seminal Quality
The microbiome plays an important role in health and in some unknown etiologies. Some previous studies have identified bacteria in semen as a potential factor in male infertility.
- Trial name
- NCT04784260
- Testing
- Microbiome analysis
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Infertility, Female, Trauma, Psychological
Adverse Childhood Experiences and Infertility : ACESI
Adverse childhood experiences can have powerful effects on health and quality of life in adulthood. Thus, having a history of childhood trauma, before the age of 18 (physical aggression, sexual abuse, death of a close person…
- Conditions
- Infertility, Female, Trauma, Psychological, Child Development, Child Abuse
- Trial name
- ACESI (NCT05952427)
- Testing
- ACE Questionnaire
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Anesthesia, Local
A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution
A Phase 3, randomized, placebo-controlled, double-masked, parallel study in healthy subjects. It is designed to evaluate the ocular safety of a single topical ocular administration of AG-920 sterile topical ophthalmic solution…
- Trial name
- NCT05501860
- Testing
- AG-920
- Where
- 2 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Infertility
Assessment of the INVOcell Culture Device When Used for up to Five-Day Incubation
The INVOcell Culture Device received de novo request for 3-day intravaginal incubation. The device is held in place with the intravaginal cavity by a Retention Device.
- Trial name
- NCT04644380
- Testing
- INVOcell
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- INVO Bioscience, Inc.
Infertility
Does Clomiphene Citrate Used for Induction of Ovulation Effect Levels of AMH and Inhibin B
100mg clomiphene citrate used for ovulation induction. The investigators take blood sample at 3 and 10 days of menstruation and count AMH and inhibin B.
- Trial name
- NCT02036411
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Infertility
The Impact of Lifestyle Behaviors on In Vitro Fertilization (IVF) Outcome
Many women undergoing in vitro fertilization (IVF) ask their doctor if there are any behaviors they should avoid, or any behaviors they should emphasize during their IVF cycle.
- Trial name
- NCT01119391
- Testing
- There was no intervention; this was a survey only study
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
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