Clinical trials: Sterility
Oligospermia
A Preliminary Study on Effect of Omega-3 on Human Sperm
The phospholipids of mammalian spermatozoa possess a distinctive fatty acid composition with high proportion of long chain polyunsaturated fatty acids.
- Trial name
- NCT00479960
- Testing
- commercially available omega-3 fatty acids supplementation
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Unexplained Infertility
Endometrial Injury in Women With Unexplained Infertility
Women between 18-39 years old who had been infertile (primary or secondary) for at least 1 year were recruited. In a parallel assignment eligible participants were randomized to receive either a single, site-specific endometrial…
- Trial name
- NCT02628756
- Testing
- Endometrial injury
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura Integrated Fertility Center
PCO - Polycystic Ovaries, Infertility
Mild Stimulation Protocol Using Clomiphene Citrate for Women With PCOS Undergoing in Vitro Fertilization
Infertility is of increasing significance affecting almost 48.5 million couples around the world. Anovulation is a major cause of infertility in women with polycystic ovary syndrome (PCOS) accounting for about 80% of women with…
- Trial name
- NCT04157725
- Testing
- mild stimulation protocol: oral Clomiphene Citrate, Conventional Stimulation Protocol: will receive FSH/HMG
- Where
- Lebanon
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Infertility Due to Nonimplantation
Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle
Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have…
- Trial name
- Compaction (NCT05960370)
- Testing
- Observational non intervention study
- Where
- Spain
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Oncology, Fertility Issues
Percutaneous Laparoscopy for Ovarian Tissue Cryopreservation.
To compare surgical outcomes of oncologic patients that underwent conventional laparoscopy and percutaneous laparoscopy for cryopreservation of ovarian tissue.
- Conditions
- Oncology, Fertility Issues, Surgery
- Trial name
- NCT05134090
- Testing
- Ovaian tissue explant
- Where
- Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Infertility
The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles
There are two main cycle regimens used for endometrial preparation for frozen embryo transfer （FET) in women with irregular cycles: hormone replacement therapy cycles (HRT) in which the endometrium is artificially prepared by…
- Trial name
- NCT01780610
- Testing
- Letrozole and human chorionic gonadotrophin, estradiol and progesterone
- Where
- China
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infertilities
Comparison of the Efficiency of Intra-uterine Insemination and in Vitro Fertilization in Women Over 37 Years
As age increases the chances for a woman to become pregnant decrease as well spontaneously as through assisted reproductive technologies (ART).
- Trial name
- AMPAGE (NCT02001870)
- Testing
- In Vitro Fecundation (IVF), Intra Uterine Insemination (IUI)
- Where
- 12 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Infertility
A Comparison of Two Freezing Techniques
The purpose of this study is to determine the best way to freeze eggs in order to preserve the fertility potential of young women.
- Trial name
- NCT00852306
- Testing
- oocyte freezing
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Infertility Assisted Reproductive Technology
The Impact of Uterine Immunity and Its Alterations on the Embryo Implantation Process
Evaluation of uterine immunity, histological picture, and endometrial microbiome for embryo implantation
- Trial name
- UTIMEE (NCT07120958)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Momo Fertilife
Infertility
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
- Trial name
- NCT01986374
- Testing
- HCG is introduced
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Servy Massey Fertility Insititute
Recurrent Pregnancy Loss, Unexplained Infertility
Assessing the Endometrial Environment in Recurrent Pregnancy Loss and Unexplained Infertility
The purpose of this study is to determine if patients with recurrent pregnancy loss or unexplained infertility have an altered uterine gene expression or uterine microbiome (micro-organism composition) during the window of embryo…
- Trial name
- NCT03401918
- Testing
- Uterine ERA and microbiome testing, Oral antibiotics and vaginal probiotics
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infertility
Comparison of Alternative Embryo Culture Systems
This study will compare two alternative embryo culture systems. Embryos from each patient will be randomly assigned to one of two systems. One group will be cultured conventionally in oil-covered droplets in dishes.
- Trial name
- NCT02028897
- Testing
- Conventional embryo culture, Enclosed embryo culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Infertility
Progesterone Microspheres Pharmacokinetic - Pharmacodynamic (PK-PD) Study
Phase: I pharmacokinetic - pharmacodynamic (PK-PD) study. Main objective: To establish the minimum effective dose of progesterone microspheres suspension, which administered by weekly intramuscular injection, will be able to…
- Trial name
- NCT01176175
- Testing
- Progesterone
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Productos Científicos S. A. de C. V.
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome
This study intends to explore the correlation between cervical microbiome, gut microbiome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to explore the…
- Trial name
- NCT05521295
- Testing
- no intervention
- Where
- China
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Infertility
Corifollitropin Alfa Versus Recombinant Follicle Stimulating Hormone (FSH) in Ovarian Stimulation of Women Undergoing in Vitro Fertilisation
The use of corifollitropin alfa is superior in terms of pregnancy outcome parameters as compared to recombinant follicle stimulating hormone (FSH) during ovarian stimulation protocols in women undergoing in vitro fertilisation.
- Trial name
- NCT01319695
- Testing
- corifollitropin alfa, recombinant follicle stimulating hormone (FSH)
- Where
- 2 sites in Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Subfertility
Preimplantation Genetic Testing for Aneuploidy of Polar Bodies
This study intends to randomly group the patients with advanced maternal age and poor ovarian response, and the study group will undergo polar body biopsy, and the next-generation sequencing(NGS) technology will be used to…
- Trial name
- NCT04538560
- Testing
- polar body biopsy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility
Navigating Health Insurance Selection for IVF Benefits
The purpose of this study is to evaluate the effectiveness of an educational intervention on health insurance literacy and utilization of in vitro fertilization (IVF) insurance benefits.
- Trial name
- NCT05663645
- Testing
- Health insurance educational guide
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Infertility
IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial.
Prospective randomised controlled trial: 3 IUI cycles versus 1 IVF/ICSI cycle in women aged 38-42 years.
- Trial name
- NCT01992731
- Testing
- Drug: Follitropine Bèta
- Where
- Belgium
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Tolerability and Satisfaction With Evie
The purpose of this study is to determine patient satisfaction and tolerability of the Evie® slow-release insemination device for US population.
- Trial name
- NCT01969812
- Testing
- Evie Slow-release Insemination Device, Traditional Intrauterine Insemination
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Infertility
Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern
Controlled ovarian stimulation (COS) for FIV increases progesterone (P) and estradiol (E2) serum levels in supraphysiologic concentrations at the end of follicular phase.
- Trial name
- NCT01391845
- Testing
- ulipristal acetate
- Where
- Argentina
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Programa de Asistencia Reproductiva de Rosario
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