Clinical trials: Sternotomy
Postoperative Pain
Ropivacaine After Sternotomy
Continuous ropivacaine infusion to sternotomy wound after coronary artery bypass grafting (CABG) or heart valve surgery to diminish postoperative pain.
- Trial name
- NAROSYD (NCT02449486)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation (AF), Cardiac Surgery
Isolation of Pulmonary Veins Using the Box Technique in Patients Undergoing Sternotomy
Atrial Fibrillation (AF) is the most common cardiac arrhythmia worldwide, affecting approximately 2.8% of the population, with prevalence increasing with age.
- Trial name
- BoxTer (NCT07312149)
- Testing
- Collection of study data from patient records
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Post Operative Pain
Pectointercostal Block for Postoperative Pain Management After Sternotomy
This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.
- Trial name
- NCT05552417
- Testing
- Pectointercostal facial plan block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Autonomic Nerve Block
Sternotomy PIFB Block in Open Heart Surgery
The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia [MMA]), has a favorable effect…
- Trial name
- NCT06233318
- Testing
- Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Ohio State University
Pain, Postoperative
Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy
In this study we will focus on the postoperative recovery. A successful postoperative recovery should bring the patient to at least to the pre-surgical level.
- Trial name
- NCT00572208
- Testing
- Gabapentin group
- Where
- 2 sites in Denmark
- Volunteers
- 64 people
- Sponsor
- Aarhus University Hospital
Cardiac Surgery Requiring Cardiopulmonary Bypass and Median Sternotomy, Cardiopulmonary Bypass
Safety and Hemostatic Efficacy of Fibrin Sealant Vapor Heated, Solvent/Detergent Treated (FS VH S/D) Compared With Currently Licensed TISSEEL VH Fibrin Sealant in Subjects Undergoing Cardiac Surgery
The objective of this study is to demonstrate equivalent hemostatic efficacy and safety between FS VH S/D and TISSEEL VH fibrin sealant in subjects undergoing cardiac surgery requiring cardiopulmonary bypass.
- Conditions
- Cardiac Surgery Requiring Cardiopulmonary Bypass and Median Sternotomy, Cardiopulmonary Bypass, Sternotomy
- Trial name
- NCT00161733
- Testing
- Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D), TISSEEL VH fibrin sealant
- Where
- 22 sites in United States
- Sponsor
- Baxter Healthcare Corporation
Chronic Postsurgical Pain
Effectiveness of Myofascial Release in Patients With Chronic Post Sternotomy Pain Syndrome
The main aim of this study is to investigate the effectiveness of Myofascial release in patients with chronic sternotomy pain.
- Trial name
- NCT06630208
- Testing
- Myofascial release, Breathing exercises, Pharmacological treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cardiac Surgery, Postoperative Pain
Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery
Even though Erector Spinae Plane (ESP) Block is shown to be efficient in cardiac surgery, the Combine Serratus Anterior Plane (CSAP) Block is still controversial if it has an efficient analgesic effect for sternotomy and drain…
- Conditions
- Cardiac Surgery, Postoperative Pain, Regional Anesthesia Morbidity
- Trial name
- NCT05308797
- Testing
- ESP block, CASP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Pain
ABC Blocks for Cardiac Surgery
This randomized blinded trial aims to evaluate the effect of parasternal intercostal and rectus sheath blocks ("anterior blocks for cardiac surgery" or ABC blocks) on postoperative recovery in patients undergoing median…
- Trial name
- NCT05589363
- Testing
- ABC block with bupivacaine/liposomal bupivacaine, ABC block with saline
- Where
- United States
- Sponsor
- Duke University
Postoperative Pain, Cardiac Surgery
ASPB-PIPB Combination in Cardiac Surgery
Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications.
- Conditions
- Postoperative Pain, Cardiac Surgery, Cardiopulmonary Bypass, Median Sternotomy
- Trial name
- NCT07716943
- Testing
- Combined ASPB and PIPB, Anterior Serratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Minimally Invasive Cardiac Valvular Surgery
Valvular Surgery: Minimally Invasive vs Conventional Sternotomy
The conventional approach to heart valve operations is through a sternotomy. This involves a vertical incision in the sternum (breastbone) to gain access to the heart and its related structures.
- Trial name
- NCT04514315
- Testing
- Minimally invasive cardiac valvular surgery, Conventional cardiac valvular surgery
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Chronic Pain, Sternotomy
Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
This study will investigate the influence of intra-operative use of remifentanil versus fentanyl on the percentage of patients with chronic thoracic after cardiac surgery via sternotomy.
- Conditions
- Chronic Pain, Sternotomy, Remifentanil, Fentanyl
- Trial name
- REFLECT (NCT02031016)
- Testing
- Fentanyl, Remifentanil
- Where
- Netherlands
- Volunteers
- 126 people
- Sponsor
- St. Antonius Hospital
Scar
Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection
Linear hypertrophic scar is a common surgical problem that can be difficult to manage, especially for the median sternotomy scar.
- Trial name
- NCT02886988
- Testing
- Botulinum toxin type A, normal saline
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Xijing Hospital
Postoperative Pain, Cardiac Surgery
Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and…
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
- Trial name
- SPARE-CABG (NCT07498946)
- Testing
- Thoracic paravertebral block (TPVB), Bilateral Deep Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Sternotomy
Percutaneous Ketamine Versus Lidocaine for Mid-Sternotomy
Since midsternotomy is painful postoepratively, and since ketamine has been shown to be optimal postoeprative analgessic adjuvant, the investigators wish to assess its percutaneous preemptive effect, comparing it to lidocaine…
- Trial name
- NCT00822419
- Testing
- lidocaine, ketamine, non-drug cream
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Analgesia
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block
In 2012 Blanco et al. [1] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries.
- Trial name
- NCT06636578
- Testing
- dexmedetomidine, ropivacaine, fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Wound, Wound Heal
Class iv Versus Class Iiib Laser Therapy on Median Sternotomy Healing After Coronary Artery Bybass Graft
LASER therapy is potent physiotherapy modalities, providing better sternotomy healing for patients who have undergone CABG surgery, compared with traditional wound care management alone.
- Conditions
- Wound, Wound Heal, Wound Infection
- Trial name
- wounds (NCT05853237)
- Testing
- laser therapy for wound management
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Heidy F. Ahmed
Cardiac Surgery, Sternotomy
Affecting Factors for Chronic Pain After Sternotomy
Chronic pain is common complication of surgery procedures. Rates of mortalits is getting lower in cardiac surgery. This situation has brought us to focus morbidity and long term life quality.
- Conditions
- Cardiac Surgery, Sternotomy, Pain, Acute, Pain, Chronic
- Trial name
- NCT06534372
- Testing
- Open cardiac surgery with sternotomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara Etlik City Hospital