Clinical trials: Sternotomy Wound
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Wound, Wound Heal
Class iv Versus Class Iiib Laser Therapy on Median Sternotomy Healing After Coronary Artery Bybass Graft
LASER therapy is potent physiotherapy modalities, providing better sternotomy healing for patients who have undergone CABG surgery, compared with traditional wound care management alone.
- Conditions
- Wound, Wound Heal, Wound Infection
- Trial name
- wounds (NCT05853237)
- Testing
- laser therapy for wound management
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Heidy F. Ahmed
Wound Infection
A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery
Following closure of surgical incisions, wounds may develop redness, swelling, and drainage which may result in increased pain and infection.
- Trial name
- NCT00576745
- Testing
- Vicryl Suture, 3M TM S Surgical Skin Closure System
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- American Heart Association
Coronary Artery Disease, Coronary Artery Stenoses
Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride
The aim of this study is to evaluate the analgesic efficacy and safety of wound infiltration with liposomal bupivacaine (LB) in patients undergoing cardiac surgery with sternotomy and cardiopulmonary bypass (CPB) and compare it…
- Conditions
- Coronary Artery Disease, Coronary Artery Stenoses, Valve Regurgitation, Mitral, Valve Regurgitation, Tricuspid
- Trial name
- NCT03270514
- Testing
- Exparel Injectable Product, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kathirvel Subramaniam
Median Sternotomy
Study to Evaluate the Safety and Efficacy of Dermal Injections of JVS-100 Given to Adults Receiving Median Sternotomy
This study will investigate the safety and efficacy of using JVS-100 to accelerate wound healing and reduce scar formation in subjects receiving surgical incisions ("sternotomies") during cardiovascular surgery.
- Trial name
- NCT01657045
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- SironRX Therapeutics, Inc.
Sternal Wound Complications, Obesity (Body Mass Index >30 kg/m2)
Sternal Closure in High-BMI Patients: Cable vs Wire
This retrospective study compares two sternal closure techniques-standard stainless-steel wires and rigid cable systems-in adult patients with a body mass index (BMI) ≥30 who underwent open-heart surgery between January 1, 2020…
- Conditions
- Sternal Wound Complications, Obesity (Body Mass Index >30 kg/m2), Median Sternotomy, Cardiac Surgery
- Trial name
- NCT07097272
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Samsun University
Pain, Postoperative, Pain Management
Bilateral Serratus Intercostal Plane Block for Myocardial Revascularization (SERRINT)
Two-parallel arm, double-blind, individually randomized controlled trial. Primary endpoint: Fentanyl consumption in the first 48 postoperative hours.
- Conditions
- Pain, Postoperative, Pain Management, Analgesia, Patient-Controlled, Nerve Block
- Trial name
- SERRINT (NCT03813225)
- Testing
- Bilateral serratus Intercostal plane Block
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Surgical Incision, Surgical Site Infection
Comparison of the Classical Median Sternotomy Skin Incision with the Paramedian Flap Skin Incision
The goal of this observational study is to determine the effects of a flap-shaped paramedian skin incision on protection from mediastinal infections, wound healing, and scar formation in open heart surgery performed through the…
- Conditions
- Surgical Incision, Surgical Site Infection, Keloid Scar Following Surgery
- Trial name
- NCT06725472
- Testing
- Open Heart Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia
Impaired Wound Healing, Postoperative Wound Infection-deep
A Comparison of Post-Sternotomy Dressings
The purpose of this study was to determine which of three types of dressings, a dry sterile dressing, a metallic silver dressing or an ionic silver dressing provided better patient outcomes for the post-sternotomy cardiac surgery…
- Trial name
- NCT02198066
- Testing
- Dry Sterile Dressing, Metallic Silver Dressing, Ionic Silver Dressing
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Carilion Clinic
Sternal Wound Infection, Sternal Non-union
Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain
The goal of this study is to evaluate sternal osteosynthesis, chest wall pain and return to normal activity in open heart surgery patients who had their breast bone closed either with wires or plates.
- Conditions
- Sternal Wound Infection, Sternal Non-union, Pain, Mediastinitis
- Trial name
- RESTORE (NCT00819286)
- Testing
- SternaLock Rigid Fixation Plates, wire (control)
- Where
- 6 sites in United States, Germany
- Volunteers
- 140 people
- Sponsor
- Zimmer Biomet
Deep Sternal Infection, Diabete Mellitus
The Role of Inflammatory Biomarkers in Preventing Deep Sternal Wound Infections After Sternotomy
The goal of this observational study is to reveal blood biomarkers that will have prognostic significance in terms of the development of deep wound infection following sternotomy.
- Conditions
- Deep Sternal Infection, Diabete Mellitus, Mediastinitis
- Trial name
- NCT07376070
- Where
- 2 sites in Georgia
- Volunteers
- 30 people
- Sponsor
- Levan Nebieridze
Pain Management, Wound Care
The Application of Virtual Reality Goggles During the First Wound Dressing After Open Heart Surgery
The aim of this study is to examine the effect of virtual reality glasses, a non-pharmacological method used in pain and anxiety management in nursing practices, on the pain, anxiety, and vital parameters perceived by patients…
- Conditions
- Pain Management, Wound Care, Heart Surgery, Heart Surgery Via Sternotomy
- Trial name
- NCT07068594
- Testing
- Virtual Reality Goggles
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Aydin Adnan Menderes University
Pain, Chest
Bilateral Pecto Intercostal Fascial Plane Block After Open Heart Surgeries
The objective is to test the effect of pecto intercostal fascial plane block (PIFB) as regard its impact on pain after sternotomy involved open heart surgery.
- Trial name
- PIFB (NCT04134637)
- Testing
- ultrasound, Bupivacaine Hydrochloride 5 MG/ML
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Heart Injuries
Surgical Management of Blood in the Pericardial Sac After Penetrating Trauma
Penetrating wounds to the heart may present to the emergency unit with the presence of blood in the pericardial sac as determined on ultrasound.
- Trial name
- NCT00823160
- Testing
- Sternotomy, Subxyphoid window
- Where
- South Africa
- Volunteers
- 111 people
- Sponsor
- University of Cape Town
Complete Vertical Midline Sternotomy / Cardiac Surgery
Prevention of the Risk of Complete Sternotomy Scar Dehiscence in Cardiac Surgery: A Clinical Investigation Comparing Negative Pressure Wound Therapy (NPWT) vs. Standard Dressing
Mediastinitis is the most feared infectious complication after cardiac surgery. Several risk factors are known such as: obesity, diabetes, chronic obstructive pulmonary disease, double breast sampling, immunodeficiency…
- Trial name
- PRISTER (NCT06207630)
- Testing
- Dressing Device
- Where
- 5 sites in France
- Volunteers
- 660 people
- Sponsor
- Poitiers University Hospital
Heart Diseases
Sternal Plating High Risk
Participants are being invited to participate in a research study at University Hospitals because they have heart disease and are scheduled for open heart surgery.
- Trial name
- NCT06660186
- Testing
- Rigid Sternal Fixation, Wire Cerclage
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University Hospitals Cleveland Medical Center