Clinical trials: Steroid
Snoring
Effect of Nasal Steroids in Snoring Intensity
It is anecdotally well known that patients snore more when their nose is blocked. However, the therapeutic effect of improving nasal airway patency on snoring indices remains a point of conjecture.
- Trial name
- NCT01849406
- Testing
- nasal spray Budesonide, Nasal spray Normal Saline
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- Ioannis Koutsourelakis
Asthma
Efficacy of Ciclesonide During the Cold Season in Patients Older Than 12 Years With Persistent Asthma
The aim of the study is to evaluate the efficacy of ciclesonide in patients with persistent asthma over 3 months, especially in the cold season. Ciclesonide will be inhaled by a metered-dose inhaler.
- Trial name
- ARTIST (NCT00608218)
- Testing
- Ciclesonide
- Where
- 153 sites in Germany
- Volunteers
- 2,100 people
- Sponsor
- AstraZeneca
Chronic Cough (CC), Laryngeal Disease
Efficacy of Intramuscular Steroid Injection for Chronic Cough.
The primary goal of this study is to test the hypothesis that injecting steroid intramuscularly is an effective treatment for unexplained chronic cough.
- Conditions
- Chronic Cough (CC), Laryngeal Disease, Coughing
- Trial name
- NCT06634823
- Testing
- Triamcinolone Acetonide Injectable Suspension, Saline injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Carpal Tunnel Syndrome
Dextrose, Steroid, PRP: Choosing the Right Injection for CRS Relief; a RCT
USG guided injections to relieve carpal tunnel syndrome with dextrose water or steroid or PRP
- Trial name
- NCT06349824
- Testing
- injection Dextrose water, USG machine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Inflammatory Arthritis, Immune-related Adverse Event
Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis
This study will examine the effectiveness of administering adalimumab as a treatment for patients in the early stages of steroid-dependent immune checkpoint Inhibitor associated inflammatory arthritis (ir-IA).
- Trial name
- NCT06037811
- Testing
- Adalimumab, Prednisone
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Tom Appleton
Lumbar Radiculopathy, Lumbar Disc Herniation
Treatment Response to TFESI and DRG Pulsed RF in Lumbar Spinal Stenosis and Disc Herniation
Lumbar radiculopathy caused by conditions such as lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) can lead to chronic pain and reduced quality of life.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07509580
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Chronic Planter Fascitis
Local Percutaneous Pulsed Radiofrequency Ablation Versus Ultrasound Guided Steroids Injection in Management of Pain in Cases of Chronic Planter Fascitis, Randomised Double Blinded Study
Plantar fasciitis is the one of the most common causes of painful heel in adults. It is assumed to be caused by inflammation and is typically precipitated by biomechanical stress.
- Trial name
- NCT07394894
- Testing
- Local percutaneous pulsed radiofrequency Ablation PRFA, methylprednisolone
- Volunteers
- 122 people
- Sponsor
- Assiut University
Idiopathic Retroperitoneal Fibrosis
Early Discontinuation of Steroid Treatment in Negative FDG-PET/CT Patients With Idiopathic Retroperitoneal Fibrosis
Adult patients with a diagnosis of idiopathic retroperitoneal fibrosis Prospective multicentric cohort study Intervention : administration of prednisone during 9 to 21 months at 1mg/kg/day at inclusion.
- Trial name
- METRO (NCT05428826)
- Testing
- Prednisone
- Where
- 15 sites in France
- Volunteers
- 41 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mosquito Bite
Evaluation of Anti-inflammatories in the Reduction of Bite Reactions
The purpose of this study is to evaluate two separate antiinflammatory products for the relief of symptoms through suppression of the immunological and inflammatory response following a mosquito bite.
- Trial name
- NCT01452997
- Testing
- NSAI treatment, Steroid treatment
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Lower Limb Injury
IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery
IV and included steroids have produced the same length of block prolongation in adults as if the steroid was given with the nerve block. Clinically, this has not be noticed in children.
- Trial name
- NCT03855059
- Testing
- Dexamethasone Sodium Phosphate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Covid-19 Infection, Hospitalization in Respiratory Disease Department
Protective Role of Inhaled Steroids for Covid-19 Infection
We hypothesize that inhaled steroid therapy and long acting beta 2 adrenergic agonist, widely prescribed in asthma patients, may also have a local protective effect against coronavirus infection, even in patients without asthma.
- Trial name
- INHASCO (NCT04331054)
- Testing
- 2: Usual practice + SYMBICORT RAPIHALER, 1: Usual practice
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus Type 1
Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression
This study will test whether a new islet transplant procedure will enable patients with type 1 diabetes mellitus to stop insulin therapy. Islets are cell clusters in the pancreas that contain insulin-producing cells.
- Trial name
- NCT00006505
- Testing
- Islet Transplantation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Uveitis, Posterior, Glaucoma
Prophylactic Anecortave Acetate in Patients With a Retisert Implant
Retisert implant is an effective therapy for controlling inflammation in patients with non-infectious posterior uveitis. One of the major complications of this device is the development of elevated intraocular pressure (IOP)…
- Trial name
- NCT00570479
- Testing
- anecortave acetate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Texas Retina Associates
Radicular; Neuropathic, Lumbar, Lumbosacral
Lumbar Transforaminal Epidural Dexamethasone
The aim of this study is to assess the effectiveness and safety of dexamethasone for transforaminal epidural steroid injection. A secondary aim of this study is to obtain data on the lowest most effective dose of dexamethasone…
- Trial name
- NCT01303354
- Testing
- Lumbar Transforaminal Epidural Steroid Injection
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ahadian, Farshad M., M.D.
Acute Pharyngitis
Inhaled Steroids for Acute Pharyngitis.
Background: Acute pharyngitis (AP) is a common presentation to the Emergency Department (ED). Most AP patients' who present to the ED are interested in relief their sore throat (pain).
- Trial name
- ISAP (NCT04027322)
- Testing
- Budesonide 0.25 MG/ML Inhalant Solution, Dexamethasone, Normal saline
- Where
- 3 sites in Oman
- Volunteers
- 200 people
- Sponsor
- Oman Medical Speciality Board
Intraocular Pressure
Ocular-hypertensive Response to Topical Steroids in Children After Bilateral Strabismus Surgery
This study aims to compare the effects of topical (Rimexolone versus Dexamethasone) on the IOP in children under 13 years of age who underwent bilateral strabismus surgery, and to compare the effects of topical (Rimexolone versus…
- Trial name
- NCT02816905
- Testing
- 0.1 % Dexamethasone, 0.1% Fluorometholone, 1% Rimexolone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Graft Versus Host Disease
In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus
In this study the investigators are proposing to treat patients with steroid-refractory Graft-versus-host Disease (GVHD) stabilization using IL-2 and azacitidine
- Trial name
- T-REG (NCT01453140)
- Testing
- Cyclophosphamide and Sirolimus, Low dose IL-2 with Cytoxan + Sirolimus, Low dose IL-2, low dose Vidaza, cyclophosphamide & Sirolimus
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Hackensack Meridian Health
Glomerulonephritis, Nephrotic Syndrome
Once-A-Month Steroid Treatment for Patients With Focal Segmental Glomerulosclerosis
This study will test the safety and effectiveness of a monthly dosing regimen of dexamethasone-a strong steroid medication-to treat patients with focal segmental glomerulosclerosis (FSGS).
- Trial name
- NCT00004990
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cardiac Arrest
Effect of Vasopressin, Steroid, and Epinephrine Treatment in Patients With Out-of-hospital Cardiac Arrest
Steroid use could be considered for patients with weaker adrenal function among those with post-cardiac arrest (CA) return of spontaneous circulation (ROSC), according to the former study.
- Trial name
- NCT03317197
- Testing
- Control Group, Experimental Group 1, Experimental Group 2
- Where
- South Korea
- Volunteers
- 834 people
- Sponsor
- Korea University Guro Hospital
Steroid-Refractory Acute Graft Versus Host Disease
A Study to Compare T-Guard vs Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-vs-Host Disease (BMT CTN 2002)
This is an open-label, randomized, Phase 3, multicenter trial, which has been designed to compare the efficacy and safety of T-Guard to ruxolitinib in patients with Grade III or IV Steroid-Refractory acute Graft-Versus-Host…
- Trial name
- 2002 (NCT04934670)
- Testing
- T-Guard, Ruxolitinib
- Where
- 48 sites in United States, Belgium and 7 more
- Volunteers
- 12 people
- Sponsor
- Xenikos
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