Clinical trials: Steroid
Immune Thrombocytopenia
Eltrombopag Plus Telitacicept vs. Eltrombopag Alone for Steroid-refractory/Relapsed ITP
Background: Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. Corticosteroids are first-line therapy, but about one-third of patients relapse or are refractory.
- Trial name
- NCT07687134
- Testing
- Eltrombopag
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Chronic Shoulder Pain
The Effect of Mesotherapy and Intra-articular Steroid Injection in Shoulder Pain
Patients with chronic shoulder pain will be divided randomly into mesotherapy and intra-articular steroid injection groups. Pain severity, range of motion and functional impairment will evaluated before treatment, 30 minutes and…
- Trial name
- Mesotherapy (NCT06610032)
- Testing
- Mesotherapy, Intra-articular steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Diabetic Retinopathy, Diabetic Macular Edema
Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation
This study will compare the side effects of two treatments for diabetic macular edema, in which blood vessels in the retina (tissue that lines the back of the eye) become leaky and the retina and macula (the center part of the…
- Conditions
- Diabetic Retinopathy, Diabetic Macular Edema, DME
- Trial name
- NCT00105404
- Testing
- Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Arthritis
Ultrasound Assessment of Steroid Joint Injections in Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a serious autoimmune childhood disease that encompasses several types of chronic arthritis.
- Trial name
- NCT01114243
- Testing
- Ultrasound imaging
- Where
- United States
- Sponsor
- Stanford University
the Efficacy of Ultrasound Guided Sacroiliac Injection of Ozone, Platelet Rich Plasma (PRP) or Steroid for Treatment of Sacroiliitis
Comparison Between Ultrasound Guided Ozone, Platelet-Rich Plasma or Steroid Injection in the Treatment of Sacroiliitis; a Randomized Double Blinded Controlled Study
Comparison between ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis; a Randomized Double Blinded Controlled Study
- Trial name
- NCT05914350
- Testing
- ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis, methylprednisolone acetate and lidocaine, PRP and lidocaine
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dexamethasone or Methylprednisolone; Sudden Hearing Loss; Intratympanic Steroid
Intratympanic Steroids for Sudden Hearing Loss
For patients with sudden hearing loss, the initial treatment is not usually effective. We use Dexamethasone or Methylprednisolone to be an Intratympanic steroid administration as a salvage treatment.
- Trial name
- NCT04129697
- Testing
- Dexamethasone or Methylprednisolone
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Multiple Myeloma
Steroid Sparing Treatment With in Newly Diagnosed Transplant Ineligible Patients With Multiple Myeloma
The purpose of this study is to determine the effects of daratumumab and lenalidomide without steroids for treating patients with multiple myeloma.
- Trial name
- NCT04635189
- Testing
- Daratumumab, Lenalidomide, Dexamethasone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester
Optic Neuritis
TLR-9 Antagonism in Steroid Resistant Optic Neuritis
Although idiopathic steroid resistant optic neuritis is very uncommon, there is no established treatment protocol for such patients.
- Trial name
- NCT01424735
- Testing
- Mycobacterium w.(Mw)-freeze dried extract 0.5ml
- Where
- India
- Volunteers
- 8 people
- Sponsor
- Sudhalkar Eye Hospital
Radiculopathy Lumbar
Clinical and MRI Factors Associated With Procedural Difficulty in Lumbar TFESI
The technical difficulty of transforaminal epidural steroid injection (TFESI) may be influenced by patient-related characteristics, the target spinal level, a history of lumbar surgery, the presence of spinal instrumentation, and…
- Trial name
- NCT07870720
- Volunteers
- 190 people
- Sponsor
- Selcuk University
CLIPPERS
Cortico-saving Treatments Proposed for CLIPPERS: a First Cohort
The primary objective of this study is to collect information about how CLIPPERS patients are currently being treated in France.
- Trial name
- NCT01740180
- Testing
- Data entry
- Where
- 11 sites in France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Breast Cancer
BN83495 Phase I in Post-menopausal Women
The purpose of this study is to determine the optimal biological dose (OBD) of Irosustat (BN83495) in postmenopausal women with oestrogen receptor (ER) positive locally advanced or metastatic breast cancer with disease…
- Trial name
- NCT01840488
- Testing
- Irosustat (BN83495)
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 50 people
- Sponsor
- Ipsen
Allergic Rhinitis, Tachyphylaxis
Preventing Tolerance to Oxymetazoline in Allergic Rhinitis
The investigators wish to evaluate the effects of decongestants like oxymetazoline and the lessening of this effect with time called 'tolerance'.
- Conditions
- Allergic Rhinitis, Tachyphylaxis, Rhinitis Medicamentosa
- Trial name
- NCT00846326
- Testing
- oxymetazoline-fluticasone propionate, Oxymetazoline
- Where
- 2 sites in United Kingdom
- Sponsor
- Brian J Lipworth
Allergic Conjunctivitis
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
To evaluate the efficacy of prednisolone acetate 1% ophthalmic suspension as compared to prednisolone acetate 0.12% ophthalmic suspension, loteprednol etabonate 0.2% ophthalmic suspension, and placebo (Tears Naturale® II) in the…
- Trial name
- NCT00689078
- Testing
- Prednisolone Acetate 1%, Prednisolone Acetate 0.12%, Loteprednol Etabonate 0.2%
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- ORA, Inc.
Carpal Tunnel Syndrome Pregnancy
Pregnancy-Related Carpal Tunnel Syndrome Treatment
The current retrospective study aimed to compare the effectiveness of local steroid injection plus splinting with that of local steroid injection or splinting alone.
- Trial name
- NCT06375291
- Testing
- splint /steroid injection/both
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Mersin Training and Research Hospital
Severe Persistent Asthma
Inhaled Steroids and Control of Severe Asthma
Investigational device: AKITA 2 device versus conventional metered-dose inhaler (MDI) Objectives: To explore if inhalative fluticasone application by means of the AKITA technology would result in a better symptom control in…
- Trial name
- INHALE (NCT01197482)
- Where
- 3 sites in Germany
- Volunteers
- 6 people
- Sponsor
- University of Giessen
Cervical Spine
Effect of Local Steroid Application on a Cervical Plate Versus Intravenous Steroids on Dysphagia Following Anterior Cervical Discectomy and Fusion (ACDF)
Local application of steroids in ACDF surgery will lead to decreased incidence of dysphagia compared to intravenous steroids or a control group
- Trial name
- NCT02577991
- Testing
- Decadron, Triamcinolone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Alopecia Areata
Comparison of Topical Latanoprost vs Topical Corticosteroid in Treatment of Localized Alopecia Areata
Alopecia areata (AA) is an autoimmune disease that involves the hair follicles. Topical corticosteroids are the established agents for treating this disorder.
- Trial name
- COLA (NCT02350023)
- Testing
- Topical latanoprost 0.005%, Topical betamethasone 0.05%
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Postpartum Depression, Major Depressive Disorder
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
The project aimed at identifying neuropsychobiological signatures of pharmacological sex-steroid hormone manipulations in healthy women as a risk model for depression.
- Conditions
- Postpartum Depression, Major Depressive Disorder, Postpartum Psychosis, Menopause
- Trial name
- GnRHa (NCT02661789)
- Testing
- Goserelin 3.6 mg implant
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Transsexualism
Sex Steroids and the Serotonin Transporter
The aim of this study is to prove the influence of the sex steroid hormones estrogen, progesterone and testosterone on the serotonin transporter (5-HTT) binding using positron emission tomography (PET) and the selective…
- Trial name
- NCT01065220
- Testing
- Testolactone undecanoate, Lynestrenol, Cyproterone Acetate
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Vienna
Graft Rejection
Analysis of a Beneficial Effect of Prolonges Topical Steroid Treatment After Low-risk Penetrating Keratoplasty
PURPOSE: To assess the impact of duration of topical steroid treatment on the incidence of endothelial graft rejection following normal-risk penetrating keratoplasty (PK).
- Trial name
- NCT00450996
- Testing
- Topical Steroids
- Volunteers
- 400 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
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