Clinical trials: Steroid
Autoimmune Encephalitis
Phase III Clinical Study of NPB-01 in Patients With Autoimmune Encephalitis
To compare the efficacy and safety of NPB-01 in patients with autoimmune encephalitis refractory to steroid pulse therapy using steroid pulse therapy as a control.
- Trial name
- NCT05177939
- Testing
- NPB-01, NPB-01-ME
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Nihon Pharmaceutical Co., Ltd
Asthma
A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler in Adolescents and Adults Who Have Asthma That is Not Controlled by Asthma Medications Not Containing Steroids
This is a randomized, double-blind, placebo- and open-label active controlled, parallel-group, multicenter, dose ranging study in male or female subjects ages 12 years and older with persistent asthma who are uncontrolled on…
- Trial name
- NCT01479621
- Testing
- Fp MDPI, Flovent Diskus, albuterol/salbutamol
- Where
- 189 sites in United States, Bulgaria and 7 more
- Volunteers
- 909 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Edema, Bruising
Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of medrol dosepaks (oral corticosteroids) on postoperative outcomes among patients undergoing rhinoplasty by Facial Plastic Surgeons at Vanderbilt.
- Conditions
- Edema, Bruising, Nasal Obstruction, Postoperative Pain
- Trial name
- NCT06483204
- Testing
- Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial
VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial
This is an investigator initiated randomized, placebo controlled, double blind, superiority, multi-centre clinical trial. The estimated study project period runs over 3-4 years, including pilot phase.
- Trial name
- VAST-A (NCT05139849)
- Testing
- Vasopressin; Methylprednisolone; Hydrocortisone, Sodium chloride
- Where
- 2 sites in Sweden
- Volunteers
- 1,276 people
- Sponsor
- Tiohundra AB
Low Back Pain
Wearable Devices to Monitor Efficacy of Epidural Steroid Injection in Patients With Low Back Pain
Low back pain (Lower Back Pain ) is extremely common , affecting more than 80 % of the general population in the modern world , one is considered the most common cause of disability in people under the age of 45.
- Trial name
- NCT02830607
- Testing
- Xiaomi Mi Band
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Spinal Stenosis, Low Back Pain
Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)
The broad, long-term objective of this research protocol is to improve the quality of life for patients suffering from lumbar spinal stenosis.
- Trial name
- LESS (NCT01238536)
- Testing
- Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection
- Where
- 10 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Washington
Heart Transplantation
A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients
The study is designed to evaluate whether Neoral dose optimization together with a therapeutic drug monitoring of Certican will prevent renal dysfunction as observed in the pivotal cardiac trial while maintaining the efficacy.
- Trial name
- NCT00098007
- Testing
- Everolimus (Certican)
- Where
- 28 sites in United States, Australia and 6 more
- Volunteers
- 199 people
- Sponsor
- Novartis Pharmaceuticals
Hypogonadism
Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement
There is evidence that suggests male sex hormones (androgens) play a significant role in brain (central nervous system) functioning.
- Trial name
- NCT00001412
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Graft vs Host Disease
Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease
A Phase I Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-Disease in patients who do not obtain complete remission with ruxolitinib
- Trial name
- GVHD-TReG (NCT03683498)
- Testing
- Regulatory T-cell enriched infusion
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Comparative Study, Immunosuppressive Agents
An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive Regimens
An open, single center, randomised study to investigate three different immunosuppressive regimens for de novo renal transplant recipients: 1.
- Trial name
- SterFreePlus (NCT01183247)
- Testing
- Rapamycin, Everolimus, Prednisone
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Sinusitis, Nasal Polyposis
S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps
The RESOLVE II Study is a randomized, single-blind, parallel arm, concurrently controlled, multicenter study with 300 chronic sinusitis patients who had prior endoscopic sinus surgery but present with recurrent sinus obstruction.
- Trial name
- RESOLVE_II (NCT02291549)
- Testing
- S8 Sinus Implant, Mometasone furoate nasal spray
- Where
- 40 sites in United States
- Volunteers
- 300 people
- Sponsor
- Intersect ENT
Infertility
Gonadotropin Type in Ovarian Stimulation
A key challenge facing reproductive biologists is the integration of the knowledge about oocyte-secreted factors into coherent physiological mechanisms of how oocytes govern folliculogenesis, cumulus cell function, and oocyte and…
- Trial name
- NCT02437032
- Testing
- recombinant FSH, Urinary FSH, hMG
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Tuberculous Lymphadenitis, Cervical
Steroids vs Placebo in Treatment of Tuberculous Lymphadenitis
This study will be conducted as a single blinded randomized control trial. The goal of this clinical trial is to learn about the role of low dose steroids in the resolution of tuberculous lymphadenitis.
- Trial name
- NCT06236152
- Testing
- Ferrous sulfate, Deltacortril
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Fahad Javed Awan
Phimosis
Treatment of Phimosis With Topical Steroid Cream -Double-blind, Randomized, Placebo-controlled Study
During last years topical steroid creams have been suggested to be effective treatment for non-retractable foreskin instead of circumcision.
- Trial name
- NCT01108198
- Testing
- Mometasone furoate cream, moisturizing cream
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Primary Aldosteronism, Hypertension
Steroids-Based Screening for Primary Aldosteronism
This prospective, single-center observational study aims to evaluate whether a steroid-based screening method can more accurately identify Primary Aldosteronism (PA) in hypertensive patients who remain on their usual…
- Trial name
- SAFE (NCT06941116)
- Testing
- Steroid-Based Screening (LC-MS/MS)
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Qifu Li
Osteoarthritis
"Blind" vs. Fluoroscopy-Guided Steroid Injections for Knee Osteoarthritis
To compare relative efficacy of intraarticular steroid injection using anatomic landmarks vs. fluoroscopy guided technique in decreasing knee osteoarthritis pain 1 month after the procedure.
- Trial name
- NCT02104726
- Testing
- Fluoroscopy guided steroid injection, Blind Steroid Injection
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type I
Islet Cell Transplantation Alone in Patients With Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression
SPECIFIC AIMS: 1. To reverse hyperglycemia and insulin dependency in patients with Type 1 Diabetes Mellitus by islet cell transplantation; 2.
- Trial name
- NCT00306098
- Testing
- islets
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rodolfo Alejandro
Ligament Tear Knee
Oxandrolone Multiligament Knee
This study is about healing after a rmultiligament knee reconstruction procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the principal male sex hormone…
- Trial name
- NCT05893069
- Testing
- Oxandrolone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- George F. Hatch
Immune Thrombocytopenia
Teriflunomide for Steroid-resistant/Relapse Immune Thrombocytopenia
Single-arm, open-label, single-center study to evaluate the efficacy and safety of teriflunomide for the treatment of adults with steroid-resistant/relapse immune thrombocytopenia (ITP).
- Trial name
- NCT06190145
- Testing
- Teriflunomide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Idiopathic Nephrotic Syndrome
Cyclophosphamide Versus Mycophenolate Mofetil for the Treatment of Steroid-dependent Nephrotic Syndrome in Children
Idiopathic nephrotic syndrome is steroid-sensitive in more than 90% of cases in children. However 60% of cases are steroid dependent and required treatment with immunosuppressive agent.
- Trial name
- NEPHROMYCY (NCT01092962)
- Testing
- Cyclophosphamide, Mycophenolate mofetil
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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