Clinical trials: Steroid
Nephrotic Syndrome Steroid-Dependent, Interleukin 2
Treatment of Steroid Dependent Idiopathic Nephrotic Syndrome in Children With Low Doses of Interleukin 2: a Pilot Study
NIL-2 is a clinical trial designed to evaluate the efficacy and safety of low doses of Interleukin2 in the treatment of recently diagnosed, steroid dependent idiopathic nephrotic syndrome in children.
- Trial name
- NIL-2 pilote (NCT02997150)
- Testing
- IL-2 Low dose
- Sponsor
- University Hospital, Limoges
Glucose Level Change
Analysis of Changes in Blood Glucose Spinal Epidural Nerve Block with Steroids in Patients with Low Back Pain
This study aims to investigate the effect of different doses of dexamethasone used in epidural nerve block procedures on blood sugar levels. Patients with spinal conditions such as stenosis or disc herniation will be enrolled.
- Trial name
- NCT06818617
- Testing
- Epidural steroid injection (ESI)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sung Hyun Lee
Meniere's Disease
Effects of Endolymphatic Sac Drainage With Steroids for Meniere's Disease
Meniere's disease is a common inner ear disease with an incidence of 15-50 per 100,000 population. Since Meniere's disease is thought to be triggered by an immune insult to inner ear, we examined intra-endolymphatic sac…
- Trial name
- EDSS (NCT00500474)
- Testing
- endolymphatic sac drainage with steroids
- Where
- Japan
- Volunteers
- 197 people
- Sponsor
- Osaka University
Total Knee Arthroplasty
Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty
One postoperative complication following unilateral or bilateral total knee arthroplasty is thrombosis (blood clot formation). In this prospective, double-blinded randomized controlled clinical trial, researchers are…
- Trial name
- NCT01815918
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Hospital for Special Surgery, New York
Diabetes Mellitus, Insulin-Dependent
Islet Transplantation for Type 1 Diabetes
The purpose of this study is to test whether the islet cell transplantation procedures and results from a previous study in Edmonton, Canada, can be repeated.
- Trial name
- NCT00014911
- Testing
- Islet Transplantation, Sirolimus, Tacrolimus
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 36 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Failed Back Surgery Syndrome, Low Back Pain
Epidural Steroid Injections in Post-lumbar Surgery Syndrome After Single-level Discectomy
62 patients with postlumbar surgery syndrome were randomized and divided into two groups. Transforaminal epidural steroid injection (TFESI) was applied to the TFESI group (n=31), and caudal epidural steroid injection (CESI) was…
- Conditions
- Failed Back Surgery Syndrome, Low Back Pain, Radiculopathy, Epidural Fibrosis
- Trial name
- NCT05099796
- Testing
- Transforaminal epidural steroid injection, Caudal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Plantar Fasciitis, Steroid
Platelet Rich Plasma Injection Compared With Steroid Injection for the Treatment of Plantar Fasciitis
Plantar fasciitis (PF) is the one of the most common orthopaedic problem resulting in heel pain. Previous evidence suggests that Platelet Rich Plasma (PRP) injection has better outcome in the long run as compared to the local…
- Conditions
- Plantar Fasciitis, Steroid, Platelet-rich Plasma (PRP)
- Trial name
- NCT04985396
- Testing
- Platelet Rich Plasma (PRP) group
- Where
- Nepal
- Volunteers
- 78 people
- Sponsor
- Armed Police Force Hospital, Nepal
Major Depressive Disorder, Perinatal Depression
The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health
Hormonal transitions such as across pregnancy and postpartum may trigger depressive episodes in some women. It is not known why, but estrogen sensitivity may play a critical role.
- Trial name
- NCT03795688
- Testing
- Pregnancy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vibe G Frøkjær, MD, PhD
Lentigines, Post Inflammatory Hyperpigmentation
Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.
- Trial name
- NCT02492373
- Testing
- topical 0.05% Clobetasol propionate ointment, Q switched Nd:YAG laser 532 nm
- Where
- Thailand
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Eosinophilic Granulomatosis With Polyangiitis
Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis.
The purpose of this study is to investigate, after achievement of remission, the efficacy of rituximab compared with azathioprine maintenance therapy on duration of remission, in patients with relapsing or newly-diagnosed…
- Trial name
- MAINRITSEG (NCT03164473)
- Testing
- Rituximab, Azathioprine
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sickle Cell Disease, Vaso-occlusive Crisis
Steroid Treatment for Sickle Cell Pain Crisis
The painful episode is the most common problem experienced by children with sickle cell disease. Although various treatments are available during painful episodes, the medication most commonly given for pain is a pain medication…
- Trial name
- NCT00263562
- Testing
- Steroid arm
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Baylor College of Medicine
Glaucoma
Triamcinolone for Ahmed Glaucoma Valve
This triple-blind, stratified, randomized clinical trial includes 100 eyes of 100 patients aged 18 to 85 years with refractory glaucoma.
- Trial name
- NCT02653963
- Testing
- Adjunctival Triamcinolone
- Where
- Iran
- Volunteers
- 106 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Sciatica
The Efficacy of Oral Steroids in the Treatment of Acute Sciatica
Sciatica (lumbosacral radiculopathy) is a common diagnosis in primary care, occurring in approximately one percent of all patients with acute low back pain.
- Trial name
- NCT00317447
- Testing
- Oral Prednisone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Kaiser Permanente
Low Back Pain, Lumbar Disc Herniation
Efficacy and Duration of Pain Relief in Transforaminal and Lumbar Sympathetic Blocks
Low back pain is a symptom that is frequently seen in the general population and reduces the quality of life of patients. Conventional medical treatment for patients with low back pain includes oral medication, lifestyle…
- Trial name
- NCT06438952
- Testing
- Transforaminal steroid injection combined with lumbar sympathetic blockade, Transforaminal steroid injection only
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bezmialem Vakif University
Asthma
Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma
Primary Objective: To evaluate the efficacy of dupilumab, compared with placebo, for reducing the use of maintenance oral corticosteroids (OCS) in participants with severe steroid-dependent asthma.
- Trial name
- VENTURE (NCT02528214)
- Testing
- Dupilumab, Oral corticosteroid therapy (prednisone/prednisolone), Inhaled corticosteroid (ICS) therapy
- Where
- 80 sites in United States, Argentina and 15 more
- Volunteers
- 210 people
- Sponsor
- Sanofi
Neuromyelitis Optica, Autoimmune Diseases
Inectolizumab With Steroid Optimization in Newly Treated NMOSD
Title: Study of Inectolizumab Combined With Steroid Hormone Adjustment Strategies in Treatment-naive Patients With Neuromyelitis Optica Spectrum Disease Objective:This study aims to evaluate the steroid-sparing effect and safety…
- Conditions
- Neuromyelitis Optica, Autoimmune Diseases, Demyelinating Autoimmune Diseases, CNS
- Trial name
- NCT07159893
- Testing
- Inebilizumab + Rapid Steroid Tapering group, Inebilizumab + Standard Steroid Tapering group
- Volunteers
- 25 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Relapsed or Refractory Large B-cell Lymphoma
Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphoma
The goal of this clinical study is to learn more about the study drug, axicabtagene ciloleucel, in participants with relapsed or refractory large B-cell lymphoma (LBCL) in the outpatient setting.
- Trial name
- ZUMA-24 (NCT05459571)
- Testing
- Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine
- Where
- 16 sites in United States
- Volunteers
- 35 people
- Sponsor
- Kite, A Gilead Company
Cardiac Surgical Procedures, Cardiopulmonary Bypass
Steroids In caRdiac Surgery Trial (SIRS Trial)
SIRS trial is a large simple study in which high-risk patients undergoing cardiac surgery requiring the use of cardiopulmonary bypass (CPB) are randomly allocated to receive a pulse dose of Methylprednisolone or a matching…
- Conditions
- Cardiac Surgical Procedures, Cardiopulmonary Bypass, Systemic Inflammatory Response Syndrome
- Trial name
- NCT00427388
- Testing
- Methylprednisolone
- Where
- Canada
- Volunteers
- 7,507 people
- Sponsor
- Population Health Research Institute
Radicular; Neuropathic, Cervical, Neck Pain
C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Cervical radicular pain is a common, disabling problem, occurs in 83:100,000 individuals per year. Symptoms are most often caused by intervertebral disc herniation (21.9%) or central or foraminal stenosis from spondylosis…
- Trial name
- NCT02095197
- Testing
- Triamcinolone 80mg
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Northwestern University
Breast Cancer
Protocol to Examine Methylation of Tumor Suppression Genes in Women at High Risk of Developing Breast Cancer
A study to examine the correlations between methylation of various genes associated with breast cancer and proliferation and cytomorphology in breast epithelial cells acquired by random periareolar fine needle aspiration of women…
- Trial name
- NCT00323908
- Volunteers
- 281 people
- Sponsor
- Carol Fabian, MD
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