Clinical trials: Steroids
Congenital Adrenal Hyperplasia, Exercise Capacity
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH
Congenital Adrenal Hyperplesia (CAH) is a group of automosal recessive disorders that develop due to a deficiency of one of the five enyzmes necessary for cortisol synthesis in the adrenal cortex.
- Conditions
- Congenital Adrenal Hyperplasia, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06449456
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Graft Versus Host Disease
Identification of Novel Targetable Kinases in SR-a GvHD
In this study, the investigators aim to identify novel targetable kinases in SR-a GvHD patient samples and investigate their role in different immune cell subtypes.
- Trial name
- NCT04342442
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Freiburg
Post-operative Edema, Steroid Use
Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery
The current standard of care at the Oral and Maxillofacial Department at the CDHA is the use of one gram of methylprednisolone administered intravenously prior to orthognathic surgery. This is largely based on the work of Habal.
- Trial name
- NCT03190642
- Testing
- Methylprednisolone
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jean Charles Doucet
Tendinopathy
The Effect of High Volume Injection With and Without Steroid in Chronic Achilles Tendinopathy
The aim of the study is to determine the effect of steroid in High Volume Injection (HVI) compared to HVI without steroid (volume effect) in functional outcomes and ultrasound tendon thickness and Color Doppler activity in…
- Trial name
- NCT02839577
- Testing
- High Volume injection without corticosteroid, High Volume injection with corticosteroid
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pediatric Steroid-Induced Ocular Hypertension and Glaucoma
Management Pediatric Steroid Induced Glaucoma
Purpose: To compare the efficacy and safety of ab externo circumferential suture trabeculotomy (ACST) and non-penetrating deep sclerectomy (NPDS) in children with steroid-induced ocular hypertension or glaucoma over 24 months.
- Trial name
- NCT04673201
- Testing
- Group B: Non-Penetrating Deep Sclerectomy (NPDS), Group A: Ab Externo Circumferential Suture Trabeculotomy (ACST)
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Trigger Finger
Percutaneous Release vs Steroid Injection for Trigger Finger
Trigger fingers (TF) is the common cause of pain and disturbed function of hand. Many studies show that percutaneous release of A1 pulley has better outcome than the steroid injection.
- Trial name
- NCT05383040
- Testing
- Percutaneous release
- Where
- Nepal
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS), is a common endocrine and metabolic condition affecting women of reproductive age.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulinemic Response, Overweight (BMI > 25)
- Trial name
- METFLEX (NCT07687264)
- Testing
- Oral Clucose Tolerance Test (oGTT)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy
A Drug Drug Interaction Study Between PF-06826647 And Oral Contraceptive Steroids In Healthy Female Participants
This is a Phase 1, fixed sequence, multiple dose, open label study of the effect of PF-06826647 on oral contraceptive (OC) pharmacokinetics (PK) and vice versa in healthy female participants.
- Trial name
- NCT04134715
- Testing
- PF-06826647, Oral Contraceptive (OC)
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Female Volunteers
Effect Of Multiple Dose PF-06700841 On The Pharmacokinetics Of Single Dose Oral Contraceptive Steroids
This Phase 1 study will assess the pharmacokinetic effect of multiple doses PF 06700841 (administered once a day) on a single dose of a combination oral contraceptive, in 18 healthy female participants who are not of childbearing…
- Trial name
- NCT04267250
- Testing
- PF-06700841, Ethinyl estradiol (EE) and levonorgestrel (LN)
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pregnancy, Respiratory Distress Syndrome
Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
This is a randomized placebo controlled trial to evaluate whether antenatal corticosteroids can decrease the rate of neonatal respiratory support, thus decreasing the rate of NICU admissions and improving short-term outcomes in…
- Conditions
- Pregnancy, Respiratory Distress Syndrome, Pregnancy Outcomes, Preterm Birth
- Trial name
- ALPS (NCT01222247)
- Testing
- Betamethasone
- Where
- 17 sites in United States
- Volunteers
- 2,831 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center