Clinical trials: Stiffness
Vascular Health, Autonomic Function
Vascular and Neuro-inflammatory Effects of Endurance Exercise Training in African Americans
The purpose of this study is to test the effects of endurance exercise training on arterial structure and function, and to examine potential mechanisms producing changes in arterial structure and function in young (18-35 years of…
- Trial name
- VINE (NCT01024634)
- Testing
- Endurance Exercise
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder)
The Effects of Muscle Characteristics on the Control of Shoulder Complex During Functional Movements
The movement control of shoulder joint relies not only on the glenohumeral joint, but also the critical contributions from scapulothoracic joint.
- Conditions
- Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder), Movement Disorders
- Trial name
- NCT04176692
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Forward Head Posture
Effects of Electrotherapy on Muscle Properties in Forward Head Posture
This randomized controlled trial investigates the acute effects of three electrotherapy modalities (therapeutic ultrasound, interferential current, and TENS) on the mechanical and viscoelastic properties of neck muscles in young…
- Trial name
- NCT07758530
- Testing
- Therapeutic Ultrasound (Chattanooga Intelect® Vet), Interferential Current (Chattanooga Intelect® Vet), Conventional TENS
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hypomotility, Lumbar Spine Instability
Lumbar Manipulation in Lumbar Hypomobility
The purpose of the study is to compare the immediate effects of thrust versus non-thrust lumbar manipulation in individuals with lumbar hypo-mobility on lumbar range of motion and springing force tolerance.
- Trial name
- NCT04521244
- Testing
- Thrust joint lumbar manipulation, Lumbar mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Elastography ,CKD Patients
SWE in Assessment of CKD Patients
Elastography is a developing technique to assess tissue elasticity. It is software that can be integrated to the ultrasonography machines.
- Trial name
- NCT05986812
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Aortic Stiffness, Oxidative Stress
Relationship Between Oxidative Stress and Aortic Stiffness
The goal of this clinical trial is to search about if there is any relationship between the aortic stiffness and oxidative stress response in adolescent football players.
- Conditions
- Aortic Stiffness, Oxidative Stress, Football Player
- Trial name
- NCT06590792
- Testing
- exhaustive exercise training session
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Amputation, Traumatic, Traumatic Amputation of Lower Extremity
What is the Optimal Stiffness and Height of a Running-specific Prosthesis?
The proposed study aims to characterize the effects of running-specific leg prosthetic stiffness and height during on performance during running and sprinting to optimize running-specific prosthesis prescription.
- Conditions
- Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
- Trial name
- NCT02318979
- Testing
- Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Ageing, Blood Flow Restriction (BFR) Training Effects
Comparing Vascular Responses to Aerobic Exercise With and Without Blood Flow Restriction in Young and Older Adults
Aging is a major risk factor for cardiovascular disease (CVD), contributing to progressive macrovascular and microvascular dysfunction.
- Trial name
- UNDER PRESSURE (NCT07079280)
- Testing
- Low Intensity Aerobic Exercise with Blood Flow Restriction (LIAE+BFR), High Intensity Interval Exercise (HIIE)
- Where
- Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Preeclampsia, Hypertensive Disorder of Pregnancy
Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy
The present study is a single-centre prospective study that will enrol pregnant women during their first trimester of pregnancy (11+0 - 13+6 weeks of gestation).
- Trial name
- EDIPE (NCT05999851)
- Testing
- Arterial applanation tonometry, In vivo endothelial glycocalyx measurement, Serum markers of angiogenesis and endothelial dysfunction
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pain
Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Joints and muscles disorders are common symptoms in the population. They are characterized by swelling, pain, functional impairment and morning stiffness.
- Trial name
- Easykrill (NCT02318875)
- Testing
- Kritech administration
- Where
- France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vivatech
Static Stretching
Acute Effects of Static Stretching Intensity and Duration on Muscle Viscoelastic Properties and Proprioception
The purpose of this study is to compare the acute effects of different duration and intensity of static stretching exercises on the viscoelastic properties of the hamstring muscle and the knee proprioception.
- Trial name
- NCT04182139
- Testing
- Static Stretching Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hepatocellular Carcinoma
Stiffness Measurement of Liver Tumors and Visceral Parenchyma
The investigators are measuring hepatocellular carcinoma(HCC)stiffness using Acoustic Radiation Force Impulse (ARFI) technique to enhance the diagnostic accuracy for HCC stratifications and treatment efficacy.
- Trial name
- NCT01343212
- Testing
- stiffness measurement using ARFI
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Aging, Autonomic Nervous System
Effects of a Smart Circuit Exercise Program on Health Outcomes in Community-Dwelling Older Adults
This study was conducted in collaboration with a community-based retirement facility to evaluate the clinical effectiveness of a smart, technology-assisted circuit exercise intervention for community-dwelling older adults.
- Conditions
- Aging, Autonomic Nervous System, Hemodynamics
- Trial name
- NCT07790263
- Testing
- Smart Circuit Exercise Program
- Where
- Taiwan
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Activity, Motor
Power or Plyometric Training in Older Adults
This study will compare the effects of high-speed power resistance training or plyometric jump training on muscle stiffness, jump performance and measures of daily activity in older adults living independently in the community.
- Trial name
- NCT06821321
- Testing
- Plyometric Training, Power Training
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Miami
Vascular Stiffness, Vasodilation
Effects of Betalains on Cardiovascular Health and Quality of Life
The goal of this randomized, double-blind, placebo-controlled, cross-over trial is to investigate the effects of beetroot-derived betalains on cardiovascular health, sleep and quality of life in healthy middle-aged individuals.
- Conditions
- Vascular Stiffness, Vasodilation, Sleep, Quality of Life
- Trial name
- NCT06117007
- Testing
- Betalains
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Cirrhosis, Liver, Portal Hypertension
Two-dimensional Shear Wave Elastography for Assessment of Cirrhosis and Portal Hypertension
Exploring and establishing new non-invasive risk stratification techniques for portal hypertension based on E imaging technology for measuring liver and spleen stiffness is an urgent need in this field of research.
- Trial name
- NCT06358092
- Testing
- Hepatic venous pressure gradient, Two-Dimensional Shear Wave Elastography
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Obesity, Pre-hypertension
Whole Body Vibration Combined With L-citrulline Supplementation on Cardiovascular Function and Body Composition
Arterial dysfunction contributes to the development of cardiovascular disease (CVD), which is currently afflicting millions of individuals.
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Trial name
- NCT02143817
- Testing
- L-citrulline supplementation, Whole Body Vibration Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Williams Syndrome, Supravalvular Aortic Stenosis
Impact of Elastin Mediated Vascular Stiffness on End Organs
Background: People with Williams Syndrome (WS) and supravalvular aortic stenosis (SVAS) have less elasticity in their blood vessels. This is called blood vessel stiffness.
- Conditions
- Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease
- Trial name
- NCT02840448
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Manual Therapy, Manipulation
Hip Manipulation in Basketball Players
Currently, it is difficult to find studies in the literature assessing the impact of manual therapy on preventing lower limb injuries in basketball players, which may later translate into improved strength and balance in…
- Conditions
- Manual Therapy, Manipulation, Muscles, Musculoskeletal System
- Trial name
- Manual Therapy (NCT06901089)
- Testing
- Manual therapy, Exercise
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk