Clinical trials: Stimulant Use (Diagnosis)
HIV, Drug Addiction
Treating South African Pregnant Women for Methamphetamine
The purpose of this study was to develop and initially evaluate an efficacious, comprehensive, culturally sensitive, women-centered model of care for pregnant South African women by adapting and refining PI Jones'…
- Trial name
- NCT01386138
- Testing
- Psycho-education, Experimental
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- RTI International
Cannabis Use Disorder, Stimulant Use Disorder
Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study
The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health problems related to addiction.
- Conditions
- Cannabis Use Disorder, Stimulant Use Disorder, Opioid Use Disorder, Tobacco Use Disorder
- Trial name
- NCT07001371
- Testing
- Emotional Brain Training, Standard addiction counseling and medical therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Loma Linda University
Opioid Use Disorder, Injection Related Infections
Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use
This is a two-group randomized controlled trial conducted at five hospitals across the U.S. designed to test the effectiveness of an Integrated infectious diseases/Substance Use Disorder outpatient clinic (IC) compared to…
- Conditions
- Opioid Use Disorder, Injection Related Infections, Stimulant Use Disorder
- Trial name
- CHOICE-STAR (NCT06513156)
- Testing
- Integrated Infectious Diseases and Substance Use Disorder Clinic (IC)
- Where
- 4 sites in United States
- Volunteers
- 304 people
- Sponsor
- Elana Rosenthal
Human Immunodeficiency Virus, Smoking Cessation
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
Smokers living with HIV represent a major health disparity population in the United States and the world more generally. Major contributing factors to the maintenance and relapse of smoking among smokers living with HIV include…
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking
- Trial name
- NCT03904186
- Testing
- QUIT, Time-Matched Control (TM)
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Stimulant Use, Stimulant-Related Disorder
The Longitudinal Study of Stimulant Use Disorder
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation.
- Conditions
- Stimulant Use, Stimulant-Related Disorder, Healthy
- Trial name
- STIM-RAD (NCT06073340)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Burnout, Secondary Trauma
PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)
The investigators propose to test the effectiveness of PATH (Peer Advanced Training for total Health) as an educational workforce intervention for improving peer recovery support specialists' (PRSS) overdose prevention (OP)…
- Conditions
- Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder
- Trial name
- NCT07886944
- Testing
- PATH (Peer Advanced Training for total Health)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Chestnut Health Systems
Obesity, Methamphetamine Use Disorder
An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder
This open label pilot study will assess the feasibility and preliminary efficacy of tirzepatide which will be prescribed under its FDA approved weight management indication in adults with moderate or severe methamphetamine…
- Conditions
- Obesity, Methamphetamine Use Disorder, Cocaine Use Disorder, Stimulant Use Disorders
- Trial name
- TRI-MR (NCT07693608)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Texas Southwestern Medical Center
Stimulant Use Disorder, Cocaine Use Disorder
LDART for Stimulant Use Disorder
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a digital intervention called LDART in adults with stimulant use disorder.
- Conditions
- Stimulant Use Disorder, Cocaine Use Disorder, Methamphetamine Use Disorder
- Trial name
- LDART (NCT07221396)
- Testing
- LDART, Psychoeducational booklet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
This research is being done to evaluate if NRP104 is a safe drug. The other purpose is to learn if NRP104 produces a high and any other effects like amphetamine and other stimulant drugs that are abused.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00248092
- Testing
- NRP104
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Methamphetamine Abuse, Methamphetamine-dependence
Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is becoming an increasing public health concern in Canada. While the evidence on the efficacy and safety of prescription psychostimulants for the treatment of MUD is promising, the knowledge on…
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance Abuse
- Trial name
- NCT06788587
- Testing
- LDX-01 plus TAU
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stimulant Use, Relapse
Relapse Prevention in Stimulant Use Disorder
The purpose of this study is to assess the relationship between bupropion, stimulant use and relapse, ADHD (Attention Deficit Hyperactivity Disorder), and measures of mood, drug craving, and inhibitory control in individuals…
- Conditions
- Stimulant Use, Relapse, Cognitive Function, ADHD
- Trial name
- NCT04553263
- Testing
- Contrave 8Mg-90Mg Extended-Release Tablet, Bupropion
- Where
- United States
- Sponsor
- University of California, Los Angeles
Stimulants Use Disorder
Deep Transcranial Magnetic Stimulation for Stimulants Use Disorder
The purpose of the study is to explore the Feasibility, Tolerability and Safety of the H7-Coil deep Transcranial Magnetic Stimulation for Subjects with Stimulants Use Disorder (SUD).
- Trial name
- NCT05274828
- Testing
- H7-Coil Deep TMS for CUD
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stimulant Use Disorder, People Living With HIV
reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)
The purpose of this study is to find out if reSET, an FDA authorized mobile therapeutic, is effective in treating stimulant use disorder and helping keep HIV viral load suppression stable among men who have sex with men who are…
- Trial name
- COSTA (NCT05958017)
- Testing
- reSET, Standard of care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Miami
Alcohol Abuse, Cannabis Abuse
Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
- Trial name
- NCT00108407
- Testing
- Integrated Cognitive Behavioral Therapy, Twelve Step Facilitation Therapy
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Stimulant Use Disorder
Mirtazapine for the Treatment of Methamphetamine Use in Opioid Use Disorder Patients Receiving Medication Assisted Treatment
This project will evaluate the ability of Mirtazapine (MZP), a pharmacologically unique medication with a growing body of evidence to support its efficacy and safety for the treatment of methamphetamine (MA) use among medication…
- Trial name
- MIRROM (NCT06323837)
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington State University
Methamphetamine Use Disorder
Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study
Methamphetamine use disorder is a major public health concern in Australia and globally. GLP-1 medications such as semaglutide (e.g.
- Trial name
- SHIFT (NCT07509112)
- Testing
- 12 weeks of weekly subcutaneous semaglutide injection
- Where
- 5 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Kirby Institute
Opioid Abuse (Disorder), Stimulant Use Disorders
Optimizing Pregnancy and Treatment Interventions for Moms 3.0
We want to learn if Patient Navigation helps pregnant Medicaid members with opioid use disorder, with or without stimulant use disorder, stay in care, use medications for opioid use disorder, reduce substance use, and connect…
- Trial name
- OPTI-Mom (NCT07586917)
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 429 people
- Sponsor
- University of Utah
Amphetamine Use Disorders
Closed-loop tTIS Targeted of the Nac as an Intervention for MUD Patients
Closed-loop transcranial temporal interference stimulation (tTIS) targeting the nucleus accumbens may modulate abnormal neural responses to drug-related cues in individuals with methamphetamine use disorder (MUD), thereby…
- Trial name
- NCT07802223
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Mental Health Center
Accidental Overdose of Opiate
Remote Intervention to Prevent Overdose
This Type 1 hybrid effectiveness-implementation randomized controlled trial, A Remote Intervention to Prevent Overdose among People who Use Stimulants and/or Opioids, aims to address the United States opioid crisis driven by…
- Trial name
- NCT07128485
- Testing
- Overdose prevention resources, Overdose prevention education
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham